Foot-and-Mouth Disease Virus 3C Protease Cleaves NEMO To Impair Innate Immune Signaling

Viral Mediated Redirection of NEMO/IKKγ to Autophagosomes Curtails the Inflammatory Cascade

(2012) Patricia M. Fliss et al.   PLoS Pathogens

The Nonstructural Protein 1 Papain-Like Cysteine Protease Was Necessary for Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1 to Inhibit Interferon-β Induction

(2011) Xibao Shi et al.   DNA AND CELL BIOLOGY

RIG-I-like receptors: cytoplasmic sensors for non-self RNA

(2011) Hiroki Kato et al.   IMMUNOLOGICAL REVIEWS

Cleavage of the Adaptor Protein TRIF by Enterovirus 71 3C Inhibits Antiviral Responses Mediated by Toll-Like Receptor 3

(2011) X. Lei et al.   JOURNAL OF VIROLOGY

The Leader Proteinase of Foot-and-Mouth Disease Virus Negatively Regulates the Type I Interferon Pathway by Acting as a Viral Deubiquitinase

(2011) D. Wang et al.   JOURNAL OF VIROLOGY

Foot-and-mouth disease virus (FMDV) leader proteinase negatively regulates the porcine interferon-λ1 pathway

(2011) Dang Wang et al.   MOLECULAR IMMUNOLOGY

Antiviral activity of bovine type III interferon against foot-and-mouth disease virus

(2011) Fayna Díaz-San Segundo et al.   VIROLOGY

Identification of the role of RIG-I, MDA-5 and TLR3 in sensing RNA viruses in porcine epithelial cells using lentivirus-driven RNA interference

(2011) Linda Hüsser et al.   VIRUS RESEARCH

Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD

(2011) Lin Qu et al.   PLoS Pathogens

The Coxsackievirus B 3Cpro Protease Cleaves MAVS and TRIF to Attenuate Host Type I Interferon and Apoptotic Signaling

(2011) Amitava Mukherjee et al.   PLoS Pathogens

Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced type I interferon transcription by decreasing interferon regulatory factor 3/7 in protein levels

(2010) Dang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKK  and DDX3

(2010) S. Yu et al.   JOURNAL OF GENERAL VIROLOGY

Porcine Type I Interferon Rapidly Protects Swine Against Challenge with Multiple Serotypes of Foot-and-Mouth Disease Virus

(2010) Camila C.A. Dias et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The 3C Protein of Enterovirus 71 Inhibits Retinoid Acid-Inducible Gene I-Mediated Interferon Regulatory Factor 3 Activation and Type I Interferon Responses

(2010) X. Lei et al.   JOURNAL OF VIROLOGY

Deubiquitinating and Interferon Antagonism Activities of Coronavirus Papain-Like Proteases

(2010) M. A. Clementz et al.   JOURNAL OF VIROLOGY

The Cysteine Protease Domain of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 2 Possesses Deubiquitinating and Interferon Antagonism Functions

(2010) Z. Sun et al.   JOURNAL OF VIROLOGY

Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells

(2010) Oekyung Kim et al.   VIROLOGY

Nonstructural protein 1α subunit-based inhibition of NF-κB activation and suppression of interferon-β production by porcine reproductive and respiratory syndrome virus

(2010) Cheng Song et al.   VIROLOGY

Expression of exogenous IFN-α by bypassing the translation block protects cells against FMDV infection

(2009) Yi Xiong et al.   ANTIVIRAL RESEARCH

IRF3 Inhibition by Rotavirus NSP1 Is Host Cell and Virus Strain Dependent but Independent of NSP1 Proteasomal Degradation

(2009) A. Sen et al.   JOURNAL OF VIROLOGY

Biological Effect of Muller's Ratchet: Distant Capsid Site Can Affect Picornavirus Protein Processing

(2009) C. Escarmis et al.   JOURNAL OF VIROLOGY

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response

(2009) Hiroshi Ashida et al.   NATURE CELL BIOLOGY

The viral RNA recognition sensor RIG-I is degraded during encephalomyocarditis virus (EMCV) infection

(2009) Laura Papon et al.   VIROLOGY

RIG-I is cleaved during picornavirus infection

(2009) Paola M. Barral et al.   VIROLOGY

PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production

(2008) Dahai Zheng et al.   CELL RESEARCH

Evading the host immune response: how foot-and-mouth disease virus has become an effective pathogen

(2008) Marvin J. Grubman et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Immune evasion during foot-and-mouth disease virus infection of swine

(2008) William T. Golde et al.   IMMUNOLOGICAL REVIEWS

A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus Is Required for Proper Subcellular Localization and Function

(2008) T. de los Santos et al.   JOURNAL OF VIROLOGY

Signal processing by its coil zipper domain activates IKK 

(2008) S. Bloor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular cloning and functional characterization of porcine IFN-β promoter stimulator 1 (IPS-1)

(2008) Dang Wang et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Innate immune responses against foot-and-mouth disease virus: Current understanding and future directions

(2008) Artur Summerfield et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Porcine interferon-gamma protects swine from foot-and-mouth disease virus (FMDV)

(2007) Qingxia Yao et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY