Crosstalk between NFκB-dependent astrocytic CXCL1 and neuron CXCR2 plays a role in descending pain facilitation

Spinal PKC activation — Induced neuronal HMGB1 translocation contributes to hyperalgesia in a bone cancer pain model in rats

(2018) Kang An et al.   EXPERIMENTAL NEUROLOGY

IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation

(2018) Si-Jian Huang et al.   Journal of Neuroinflammation

Levo-corydalmine alleviates vincristine-induced neuropathic pain in mice by inhibiting an NF-kappa B-dependent CXCL1/CXCR2 signaling pathway

(2018) Lin Zhou et al.   NEUROPHARMACOLOGY

Activation of Astrocytes and Microglial Cells and CCL2/CCR2 Upregulation in the Dorsolateral and Ventrolateral Nuclei of Periaqueductal Gray and Rostral Ventromedial Medulla Following Different Types of Sciatic Nerve Injury

(2018) Petr Dubový et al.   Frontiers in Cellular Neuroscience

Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling

(2018) Sidra Khalid et al.   Frontiers in Pharmacology

Top-down control of pain

(2017) Lucy F. Donaldson et al.   JOURNAL OF PHYSIOLOGY-LONDON

CXCL12/CXCR4 signaling-mediated ERK1/2 activation in spinal cord contributes to the pathogenesis of postsurgical pain in rats

(2017) Fei Xing et al.   Molecular Pain

CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization

(2017) Rangel L. Silva et al.   NEUROBIOLOGY OF DISEASE

SDF1-CXCR4 Signaling Maintains Central Post-Stroke Pain through Mediation of Glial-Neuronal Interactions

(2017) Fei Yang et al.   Frontiers in Molecular Neuroscience

Electroacupuncture Attenuates Visceral Hypersensitivity by Inhibiting JAK2/STAT3 Signaling Pathway in the Descending Pain Modulation System

(2017) Juan Wan et al.   Frontiers in Neuroscience

Intrinsic functional connectivity of periaqueductal gray subregions in humans

(2016) Marie-Andree Coulombe et al.   HUMAN BRAIN MAPPING

Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice

(2016) Qian Zhang et al.   Journal of Neuroinflammation

Up-regulation of CXCL1 and CXCR2 contributes to remifentanil-induced hypernociception via modulating spinal NMDA receptor expression and phosphorylation in rats

(2016) Li-hua Yang et al.   NEUROSCIENCE LETTERS

Retracted: CXCL12/CXCR4 chemokine signaling in spinal glia induces pain hypersensitivity through MAPKs-mediated neuroinflammation in bone cancer rats

(2015) Xue-Ming Hu et al.   JOURNAL OF NEUROCHEMISTRY

CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation

(2015) Fengjiao Wu et al.   Journal of Neuroinflammation

Glial activation in the periaqueductal gray promotes descending facilitation of neuropathic pain through the p38 MAPK signaling pathway

(2015) Hua-Dong Ni et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Enhanced binding capability of nuclear factor-κB with demethylated P2X3 receptor gene contributes to cancer pain in rats

(2015) You-Lang Zhou et al.   PAIN

Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice

(2014) Gang Chen et al.   BRAIN

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice

(2014) Jie Xu et al.   Journal of Neuroinflammation

CXCL12 in astrocytes contributes to bone cancer pain through CXCR4-mediated neuronal sensitization and glial activation in rat spinal cord

(2014) Wen Shen et al.   Journal of Neuroinflammation

Contribution of Chemokine CCL2/CCR2 Signaling in the Dorsal Root Ganglion and Spinal Cord to the Maintenance of Neuropathic Pain in a Rat Model of Lumbar Disc Herniation

(2014) Xiang Zhu et al.   JOURNAL OF PAIN

Contributions of purinergic P2X3 receptors within the midbrain periaqueductal gray to diabetes-induced neuropathic pain

(2014) Jianfei Guo et al.   Journal of Physiological Sciences

Chemokine contribution to neuropathic pain: Respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons

(2013) Zhi-Jun Zhang et al.   PAIN

Inhibitory effect of the antidepressant imipramine on NF-κB-dependent CXCL1 expression in TNFα-exposed astrocytes

(2012) Young Han Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Role of Astrocytes in Pain

(2012) C.-Y. Chiang et al.   NEUROCHEMICAL RESEARCH

Chemokine signaling involving chemokine (C-C motif) ligand 2 plays a role in descending pain facilitation

(2012) Wei Guo et al.   Neuroscience Bulletin

Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity

(2011) Vito de Novellis et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats

(2011) Erik A Johnson et al.   Journal of Neuroinflammation

Spinal glia and chronic pain

(2010) James P. O'Callaghan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Anatomically specific patterns of glial activation in the periaqueductal gray of the sub-population of rats showing pain and disability following chronic constriction injury of the sciatic nerve

(2010) D. Mor et al.   NEUROSCIENCE

Neuronal Injury Induces Cytokine-Induced Neutrophil Chemoattractant-1 (CINC-1) Production in Astrocytes

(2009) Takahiro Katayama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Descending control of nociception: Specificity, recruitment and plasticity

(2008) M.M. Heinricher et al.   BRAIN RESEARCH REVIEWS

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury

(2008) K. Miyoshi et al.   JOURNAL OF NEUROSCIENCE

Supraspinal Glial-Neuronal Interactions Contribute to Descending Pain Facilitation

(2008) F. Wei et al.   JOURNAL OF NEUROSCIENCE