Mitochondrial Impairment in Oligodendroglial Cells Induces Cytokine Expression and Signaling

TNF-α-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways

(2018) Junichi Matsumoto et al.   BRAIN RESEARCH

Chemical hypoxia-induced integrated stress response activation in oligodendrocytes is mediated by the transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2)

(2018) Nico Teske et al.   JOURNAL OF NEUROCHEMISTRY

Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression

(2017) Bernhard Josef Rüther et al.   GLIA

Reduced cuprizone-induced cerebellar demyelination in mice with astrocyte-targeted production of IL-6 is associated with chronically activated, but less responsive microglia

(2017) Filip Petković et al.   JOURNAL OF NEUROIMMUNOLOGY

Macrophage inhibitory cytokine-1/growth differentiation factor 15 as a marker of cognitive ageing and dementia

(2016) Jiyang Jiang et al.   CURRENT OPINION IN PSYCHIATRY

Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model

(2016) T. Draheim et al.   GLIA

Neurodegeneration Triggers Peripheral Immune Cell Recruitment into the Forebrain

(2016) M. Scheld et al.   JOURNAL OF NEUROSCIENCE

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

(2015) Tim Clarner et al.   JOURNAL OF IMMUNOLOGY

Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration

(2015) S. Moyon et al.   JOURNAL OF NEUROSCIENCE

IL-4 Protects the Mitochondria Against TNFα and IFNγ Induced Insult During Clearance of Infection with Citrobacter rodentium and Escherichia coli

(2015) Arpan K. Maiti et al.   Scientific Reports

Role of Activating Transcription Factor 3 (ATF3) in Endoplasmic Reticulum (ER) Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-mediated Apoptosis through Up-regulation of Death Receptor 5 (DR5) by Zerumbone and Celecoxib

(2014) Makoto Edagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short-Term Cuprizone Feeding Verifies N-Acetylaspartate Quantification as a Marker of Neurodegeneration

(2014) Barbara Maria Krauspe et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Oxidative stress response elicited by mitochondrial dysfunction: Implication in the pathophysiology of aging

(2013) Chih-Hao Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cuprizone short-term exposure: Astrocytic IL-6 activation and behavioral changes relevant to psychosis

(2013) Tomoaki Tezuka et al.   NEUROBIOLOGY OF DISEASE

Growth Differentiation Factor‐15 Deficiency Inhibits Atherosclerosis Progression by Regulating Interleukin‐6–Dependent Inflammatory Response to Vascular Injury

(2013) Gabriel A. Bonaterra et al.   Journal of the American Heart Association

IL-6 promotes regeneration and functional recovery after cortical spinal tract injury by reactivating intrinsic growth program of neurons and enhancing synapse formation

(2012) Ping Yang et al.   EXPERIMENTAL NEUROLOGY

Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions

(2012) Tim Clarner et al.   GLIA

Growth differentiation factor-15 upregulates interleukin-6 to promote tumorigenesis of prostate carcinoma PC-3 cells

(2012) Ke-Hung Tsui et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

CCL5 induces a pro-inflammatory profile in microglia in vitro

(2011) Jelena Škuljec et al.   CELLULAR IMMUNOLOGY

JCV agnoprotein-induced reduction in CXCL5/LIX secretion by oligodendrocytes is associated with activation of apoptotic signaling in neurons

(2011) Nana Merabova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Meta-Analysis of Cytokines in Alzheimer's Disease

(2010) Walter Swardfager et al.   BIOLOGICAL PSYCHIATRY

Interleukin-6 is an important mediator for mitochondrial DNA repair after alcoholic liver injury in mice

(2010) Xiuying Zhang et al.   HEPATOLOGY

Nrf2 Induces Interleukin-6 (IL-6) Expression via an Antioxidant Response Element within the IL-6 Promoter

(2010) Christoph Jan Wruck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is multiple sclerosis a mitochondrial disease?

(2009) Peizhong Mao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Molecular Changes in White Matter Adjacent to an Active Demyelinating Lesion in Early Multiple Sclerosis

(2009) Thomas Zeis et al.   BRAIN PATHOLOGY

Regulatory effects of IFN-β on production of osteopontin and IL-17 by CD4+ T Cells in MS

(2009) Meiyue Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Review: Mitochondria and disease progression in multiple sclerosis

(2008) D. Mahad et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY