Role of Activating Transcription Factor 3 (ATF3) in Endoplasmic Reticulum (ER) Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-mediated Apoptosis through Up-regulation of Death Receptor 5 (DR5) by Zerumbone and Celecoxib

Non-Specific Protein Modifications by a Phytochemical Induce Heat Shock Response for Self-Defense

(2013) Kohta Ohnishi et al.   PLoS One

Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis

(2013) Praveen K. Sobhan et al.   PLoS One

Zerumbone, an electrophilic sesquiterpene, induces cellular proteo-stress leading to activation of ubiquitin–proteasome system and autophagy

(2012) Kohta Ohnishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer

(2012) Remya Prasannan et al.   BIOCHEMICAL PHARMACOLOGY

Redox signaling loops in the unfolded protein response

(2012) Arisa Higa et al.   CELLULAR SIGNALLING

PKC  Regulates Death Receptor 5 Expression Induced by PS-341 through ATF4-ATF3/CHOP Axis in Human Lung Cancer Cells

(2012) L. Xu et al.   MOLECULAR CANCER THERAPEUTICS

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics

(2012) L Y Dimberg et al.   ONCOGENE

Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: Involvement of ROS-dependent ER-stress

(2011) Dong-Oh Moon et al.   BIOCHEMICAL PHARMACOLOGY

Zerumbone Induces Heme Oxygenase-1 Expression in Mouse Skin and Cultured Murine Epidermal Cells through Activation of Nrf2

(2011) J.-W. Shin et al.   Cancer Prevention Research

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Importin β1 Protein-mediated Nuclear Localization of Death Receptor 5 (DR5) Limits DR5/Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Cell Death of Human Tumor Cells

(2011) Yuko Kojima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells

(2011) K Taketani et al.   ONCOGENE

An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man

(2010) Timothy Ravasi et al.   CELL

Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium

(2010) Shahir S. Hamdulay et al.   FREE RADICAL BIOLOGY AND MEDICINE

ERK/Ribosomal S6 Kinase (RSK) Signaling Positively Regulates Death Receptor 5 Expression through Co-activation of CHOP and Elk1

(2010) You-Take Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New insights into apoptosis signaling by Apo2L/TRAIL

(2010) F Gonzalvez et al.   ONCOGENE

In VitroCovalent Binding Proteins of Zerumbone, a Chemopreventive Food Factor

(2009) Kohta OHNISHI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species

(2009) S. Yodkeeree et al.   CANCER RESEARCH

Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway

(2008) Altin Gjymishka et al.   BIOCHEMICAL JOURNAL

Aggravated Endoplasmic Reticulum Stress as a Basis for Enhanced Glioblastoma Cell Killing by Bortezomib in Combination with Celecoxib or Its Non-Coxib Analogue, 2,5-Dimethyl-Celecoxib

(2008) A. Kardosh et al.   CANCER RESEARCH

OSU-03012, a Novel Celecoxib Derivative, Induces Reactive Oxygen Species-Related Autophagy in Hepatocellular Carcinoma

(2008) M. Gao et al.   CANCER RESEARCH

Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice

(2008) Mihye Kim et al.   INTERNATIONAL JOURNAL OF CANCER

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY