Hypoxia-inducible factor 1α protects peripheral sensory neurons from diabetic peripheral neuropathy by suppressing accumulation of reactive oxygen species.

Renal injury is accelerated by global hypoxia-inducible factor 1 alpha deficiency in a mouse model of STZ-induced diabetes

(2017) Romana Bohuslavova et al.   BMC Endocrine Disorders

Neuropathic pain

(2017) Luana Colloca et al.   Nature Reviews Disease Primers

Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes

(2016) Manasi S. Shah et al.   CIRCULATION RESEARCH

HIF-1α pathway: role, regulation and intervention for cancer therapy

(2015) Georgina N. Masoud et al.   Acta Pharmaceutica Sinica B

Wnt-Fzd Signaling Sensitizes Peripheral Sensory Neurons via Distinct Noncanonical Pathways

(2014) Manuela Simonetti et al.   NEURON

Hypoxia-Inducible Factor 1 Regulates Heat and Cold Pain Sensitivity and Persistence

(2013) Maike Kanngiesser et al.   ANTIOXIDANTS & REDOX SIGNALING

Transcriptional regulation by hypoxia inducible factors

(2013) Veronica L. Dengler et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hyperglycemia-induced Oxidative Stress and its Role in Diabetes Mellitus Related Cardiovascular Diseases

(2013) Teresa Fiorentino et al.   CURRENT PHARMACEUTICAL DESIGN

The Possible Mechanisms Underlying the Impairment of HIF-1α Pathway Signaling in Hyperglycemia and the Beneficial Effects of Certain Therapies

(2013) Haijuan Xiao et al.   International Journal of Medical Sciences

Significant changes in mitochondrial distribution in different pain models of mice

(2013) Bao-Lin Guo et al.   MITOCHONDRION

Methylglyoxal Evokes Pain by Stimulating TRPA1

(2013) David A. Andersson et al.   PLoS One

Diabetic neuropathy: clinical manifestations and current treatments

(2012) Brian C Callaghan et al.   LANCET NEUROLOGY

Overexpression of human HSP27 protects sensory neurons from diabetes

(2012) L. Korngut et al.   NEUROBIOLOGY OF DISEASE

Role of Peptidergic Nerve Terminals in the Skin: Reversal of Thermal Sensation by Calcitonin Gene-Related Peptide in TRPV1-Depleted Neuropathy

(2012) Yu-Lin Hsieh et al.   PLoS One

Development of sensory neuropathy in streptozotocin-induced diabetic mice

(2012) Tatsufumi Murakami et al.   Brain and Behavior

Cytometric assessment of mitochondria using fluorescent probes

(2011) Cécile Cottet-Rousselle et al.   CYTOMETRY PART A

Diabetic neuropathy: cellular mechanisms as therapeutic targets

(2011) Andrea M. Vincent et al.   Nature Reviews Neurology

Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release

(2011) June Yowtak et al.   PAIN

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

(2011) D R Gough et al.   Cell Death & Disease

Mechanism of diabetic neuropathy: Where are we now and where to go?

(2010) Soroku Yagihashi et al.   Journal of Diabetes Investigation

Hyperglycemia-enhanced ischemic brain damage in mutant manganese SOD mice is associated with suppression of HIF-1α

(2009) Jeffery J. Bullock et al.   NEUROSCIENCE LETTERS

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Stabilization of HIF-1  is critical to improve wound healing in diabetic mice

(2008) I. R. Botusan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA