IDH-1 deficiency induces growth defects and metabolic alterations in GSPD-1-deficient Caenorhabditis elegans

Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer

(2017) H-Q Ju et al.   ONCOGENE

Impaired embryonic development in glucose-6-phosphate dehydrogenase-deficient Caenorhabditis elegans due to abnormal redox homeostasis induced activation of calcium-independent phospholipase and alteration of glycerophospholipid metabolism

(2017) Tzu-Ling Chen et al.   Cell Death & Disease

What has passed is prolog: new cellular and physiological roles of G6PD

(2016) Hung-Chi Yang et al.   FREE RADICAL RESEARCH

Isocitrate dehydrogenase mutations in myeloid malignancies

(2016) B C Medeiros et al.   LEUKEMIA

Glucose-6-phosphate dehydrogenase deficiency and risk of colorectal cancer in Northern Sardinia

(2016) Maria P. Dore et al.   MEDICINE

ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia

(2016) Mark A. Gregory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IDH1 deficiency attenuates gluconeogenesis in mouse liver by impairing amino acid utilization

(2016) Jing Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G6PD protects from oxidative damage and improves healthspan in mice

(2016) Sandrina Nóbrega-Pereira et al.   Nature Communications

SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation

(2016) Shuang-Nian Xu et al.   Scientific Reports

Inability to Maintain GSH Pool in G6PD-Deficient Red Cells Causes Futile AMPK Activation and Irreversible Metabolic Disturbance

(2015) Hsiang-yu Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP+/NADPH ratio

(2015) M Itsumi et al.   CELL DEATH AND DIFFERENTIATION

Comparative Metabolomic Profiling Reveals That Dysregulated Glycolysis Stemming from Lack of Salvage NAD+Biosynthesis Impairs Reproductive Development inCaenorhabditis elegans

(2015) Wenqing Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans

(2015) P.G. Morgan et al.   MITOCHONDRION

Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells

(2015) Andreas Kuehne et al.   MOLECULAR CELL

Isocitrate dehydrogenase mutations in gliomas

(2015) Matthew S. Waitkus et al.   NEURO-ONCOLOGY

Inhibition of pentose phosphate pathway suppresses acute myelogenous leukemia

(2015) Yan Chen et al.   TUMOR BIOLOGY

Overexpression of G6PD is associated with high risks of recurrent metastasis and poor progression-free survival in primary breast carcinoma

(2015) Haihong Pu et al.   World Journal of Surgical Oncology

Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans

(2015) Sider Penkov et al.   Nature Communications

O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth

(2015) Xiongjian Rao et al.   Nature Communications

Glucose-6-phosphate dehydrogenase – beyond the realm of red cell biology

(2014) H.-Y. Ho et al.   FREE RADICAL RESEARCH

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

(2014) Caroline A. Lewis et al.   MOLECULAR CELL

Quantitative flux analysis reveals folate-dependent NADPH production

(2014) Jing Fan et al.   NATURE

A model of glucose-6-phosphate dehydrogenase deficiency in the zebrafish

(2013) Xiaobai Patrinostro et al.   EXPERIMENTAL HEMATOLOGY

Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension

(2013) Gary J. Patti et al.   Metabolomics

Glucose 6-phosphate dehydrogenase deficiency enhances germ cell apoptosis and causes defective embryogenesis in Caenorhabditis elegans

(2013) H-C Yang et al.   Cell Death & Disease

A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans

(2012) Cecilia Castro et al.   BMC GENOMICS

Tetraspanin Is Required for Generation of Reactive Oxygen Species by the Dual Oxidase System in Caenorhabditis elegans

(2012) Hiroki Moribe et al.   PLoS Genetics

Biochemical disorders associated with antiproliferative effect of dehydroepiandrosterone in hepatoma cells as revealed by LC-based metabolomics

(2011) Mei-Ling Cheng et al.   BIOCHEMICAL PHARMACOLOGY

A potential role for fatty acid biosynthesis genes during molting and cuticle formation in Caenorhabditis elegans

(2011) Yingxiu Li et al.   BMB Reports

Overexpression of G6PD is associated with poor clinical outcome in gastric cancer

(2011) Jixu Wang et al.   TUMOR BIOLOGY

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

(2010) Patrick S. Ward et al.   CANCER CELL

Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism

(2010) Z. J. Reitman et al.   JNCI-Journal of the National Cancer Institute

Combined Extracellular Matrix Cross-linking Activity of the Peroxidase MLT-7 and the Dual Oxidase BLI-3 Is Critical for Post-embryonic Viability inCaenorhabditis elegans

(2009) Melanie C. Thein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Metabolomic Responses ofCaenorhabditis elegansto Cadmium Are Largely Independent of Metallothionein Status, but Dominated by Changes in Cystathionine and Phytochelatins

(2009) Samantha L. Hughes et al.   JOURNAL OF PROTEOME RESEARCH

A comparative metabolomic study of NHR-49 inCaenorhabditis elegansand PPAR-α in the mouse

(2008) Helen J. Atherton et al.   FEBS LETTERS