Do cardiac actin mutations lead to altered actomyosin interactions?

The immediate effect of HCM causing actin mutants E99K and A230V on actin–Tm–myosin interaction in thin-filament reconstituted myocardium

(2015) Fan Bai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Altered interactions between cardiac myosin binding protein-c and α-cardiac actin variants associated with cardiomyopathies

(2014) Melissa L. Chow et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331P

(2014) Fan Bai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human  -cardiac myosin motor function

(2013) R. F. Sommese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Rigor Actin-Tropomyosin-Myosin Complex

(2012) Elmar Behrmann et al.   CELL

Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy

(2012) Mirco Müller et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Understanding Cardiomyopathy Phenotypes Based on the Functional Impact of Mutations in the Myosin Motor

(2012) Jeffrey R. Moore et al.   CIRCULATION RESEARCH

Subdomain Location of Mutations in Cardiac Actin Correlate with Type of Functional Change

(2012) Maureen M. Mundia et al.   PLoS One

Several cardiomyopathy causing mutations on tropomyosin either destabilize the active state of actomyosin or alter the binding properties of tropomyosin

(2011) Mohit C. Mathur et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Canadian Heart Health Strategy and Action Plan

(2011) Eldon R. Smith   CANADIAN JOURNAL OF CARDIOLOGY

Identifying Sarcomere Gene Mutations in Hypertrophic Cardiomyopathy

(2011) Christine E. Seidman et al.   CIRCULATION RESEARCH

Molecular Mechanism of the E99K Mutation in Cardiac Actin (ACTCGene) That Causes Apical Hypertrophy in Man and Mouse

(2011) Weihua Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How Do Mutations in Contractile Proteins Cause the Primary Familial Cardiomyopathies?

(2011) Steven B. Marston   Journal of Cardiovascular Translational Research

Investigation of a transgenic mouse model of familial dilated cardiomyopathy

(2010) Weihua Song et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The actin-myosin interface

(2010) Michael Lorenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitro

(2009) Edward P. Debold et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY