Independent and additive effects of PNPLA3 and TM6SF2 polymorphisms on the development of non-B, non-C hepatocellular carcinoma

The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells

(2017) Francesca Virginia Bruschi et al.   HEPATOLOGY

Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B

(2017) Anthony W H Chan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

New trends on obesity and NAFLD in Asia

(2017) Jian-Gao Fan et al.   JOURNAL OF HEPATOLOGY

Association between PNPLA3 gene polymorphisms and risk of hepatitis B virus-related hepatocellular carcinoma in Han population in China:a case-control study

(2017) Xia Gao et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

PNPLA3 rs738409 and TM6SF2 rs58542926 variants increase the risk of hepatocellular carcinoma in alcoholic cirrhosis

(2016) Edmondo Falleti et al.   DIGESTIVE AND LIVER DISEASE

Is Hepatocellular Cancer the Same Disease in Alcoholic and Nonalcoholic Fatty Liver Diseases?

(2016) Nicolas Goossens et al.   GASTROENTEROLOGY

Development of hepatocellular carcinoma in Japanese patients with biopsy-proven non-alcoholic fatty liver disease: Association between PNPLA3 genotype and hepatocarcinogenesis/fibrosis progression

(2016) Yuya Seko et al.   HEPATOLOGY RESEARCH

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans

(2016) Panu K. Luukkonen et al.   JOURNAL OF HEPATOLOGY

PNPLA3 gene in liver diseases

(2016) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

The dual and opposite role of theTM6SF2-rs58542926 variant in protecting against cardiovascular disease and conferring risk for nonalcoholic fatty liver: A meta-analysis

(2015) Carlos J. Pirola et al.   HEPATOLOGY

The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus

(2015) Misuzu Ueyama et al.   JOURNAL OF GASTROENTEROLOGY

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

(2015) Stephan Buch et al.   NATURE GENETICS

The Effect of PNPLA3 on Fibrosis Progression and Development of Hepatocellular Carcinoma: A Meta-analysis

(2014) Amit G Singal et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Pathogenesis of hepatocellular carcinoma according to aetiology

(2014) Jean-Charles Nault   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Pnpla3I148Mknockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis

(2014) Eriks Smagris et al.   HEPATOLOGY

A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease

(2014) Hans Dieter Nischalke et al.   JOURNAL OF HEPATOLOGY

The impact ofPNPLA3(rs738409C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients

(2014) Willem P Brouwer et al.   LIVER INTERNATIONAL

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

(2014) Yang-Lin Liu et al.   Nature Communications

The KIF1B (rs17401966) Single Nucleotide Polymorphism is not Associated with the Development of HBV-related Hepatocellular Carcinoma in Thai Patients

(2013) Watanyoo Sopipong et al.   Asian Pacific Journal of Cancer Prevention

Enrichment of phosphatidylinositols with specific acyl chains

(2013) Kenneth D'Souza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function

(2013) Piero Pingitore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Association between thePNPLA3(rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data

(2013) Eric Trépo et al.   HEPATOLOGY

PNPLA3 I148M Polymorphism, Clinical Presentation, and Survival in Patients with Hepatocellular Carcinoma

(2013) Luca Valenti et al.   PLoS One

The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis

(2012) Yasuto Takeuchi et al.   JOURNAL OF GASTROENTEROLOGY

Single nucleotide polymorphisms and risk of hepatocellular carcinoma in cirrhosis

(2012) Pierre Nahon et al.   JOURNAL OF HEPATOLOGY

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Management of hepatocellular carcinoma: An update

(2011) Jordi Bruix et al.   HEPATOLOGY

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Design and Endpoints of Clinical Trials in Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   JNCI-Journal of the National Cancer Institute

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS