Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis

Co-culture of ovarian cancer stem-like cells with macrophages induced SKOV3 cells stemness via IL-8/STAT3 signaling

(2018) Yingxia Ning et al.   BIOMEDICINE & PHARMACOTHERAPY

Changes in ovarian cancer survival during the 20 years before the era of targeted therapy

(2018) Jung-Yun Lee et al.   BMC CANCER

Tissue Tranglutaminase Regulates Interactions between Ovarian Cancer Stem Cells and the Tumor Niche

(2018) Salvatore Condello et al.   CANCER RESEARCH

Cross-talk between ovarian cancer cells and macrophages through periostin promotes macrophage recruitment

(2018) Meng Tang et al.   CANCER SCIENCE

Radiation Therapy in Ovarian Cancer: An Overview and Future Directions

(2018) M. McCormack   CLINICAL ONCOLOGY

Recent Progress in Gene Therapy for Ovarian Cancer

(2018) Ángela Áyen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms

(2018) Ahmed E. Hegab et al.   LUNG CANCER

Epidemiology and treatment patterns of epithelial ovarian cancer

(2017) Philip Jessmon et al.   Expert Review of Anticancer Therapy

Lithocholic Acid Stimulates IL-8 Expression in Human Colorectal Cancer Cells Via Activation of Erk1/2 MAPK and Suppression of STAT3 Activity

(2017) Thi Thinh Nguyen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

(2017) Tsukasa Shibue et al.   Nature Reviews Clinical Oncology

Inactivation of AKT, ERK and NF-κB by genistein derivative, 7-difluoromethoxyl-5,4′-di-n-octylygenistein, reduces ovarian carcinoma oncogenicity

(2017) Yingxia Ning et al.   ONCOLOGY REPORTS

STAT3/NF-κB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer

(2017) Wei-Ying Kuo et al.   Theranostics

Non-CSCs nourish CSCs through interleukin-17E-mediated activation of NF-κB and JAK/STAT3 signaling in human hepatocellular carcinoma

(2016) Yongli Luo et al.   CANCER LETTERS

Genistein-induced differentiation of breast cancer stem/progenitor cells through a paracrine mechanism

(2016) YANCHEN LIU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer

(2016) Mingzhu Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

7-Difluoromethoxyl-5,4′-di-n-octyl genistein inhibits the stem-like characteristics of gastric cancer stem-like cells and reverses the phenotype of epithelial-mesenchymal transition in gastric cancer cells

(2016) Xiaozheng Cao et al.   ONCOLOGY REPORTS

Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression

(2016) Ruihua Ma et al.   OncoImmunology

Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transition

(2015) Hong Liu et al.   CARCINOGENESIS

The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma

(2015) Euan A. Stronach et al.   Oncotarget

CECs and IL-8 Have Prognostic and Predictive Utility in Patients with Recurrent Platinum-Sensitive Ovarian Cancer: Biomarker Correlates from the Randomized Phase-2 Trial of Olaparib and Cediranib Compared with Olaparib in Recurrent Platinum-Sensitive Ovarian Cancer

(2015) Jung-Min Lee et al.   Frontiers in Oncology

Neurotensin signaling regulates stem-like traits of glioblastoma stem cells through activation of IL-8/CXCR1/STAT3 pathway

(2014) Ji Zhou et al.   CELLULAR SIGNALLING

FOXO3a-mediated suppression of the self-renewal capacity of sphere-forming cells derived from the ovarian cancer SKOV3 cell line by 7-difluoromethoxyl-5,4′-di-n-octyl genistein

(2014) YINGXIA NING et al.   Molecular Medicine Reports

7-difluoromethoxyl-5,4′-di-n-octyl genistein inhibits ovarian cancer stem cell characteristics through the downregulation of FOXM1

(2014) YING-XIA NING et al.   Oncology Letters

DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells

(2013) Thomas R. Jackson et al.   CELL CYCLE

Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties

(2013) Mona M. Mohamed et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

(2011) M. Jinushi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

7-(O)-Carboxymethyl daidzein conjugated to N-t-Boc-hexylenediamine: A novel compound capable of inducing cell death in epithelial ovarian cancer stem cells

(2010) Jamie M. Green et al.   CANCER BIOLOGY & THERAPY

Activation of STAT3 Signal Pathway Correlates with Twist and E-Cadherin Expression in Hepatocellular Carcinoma and Their Clinical Significance

(2010) Chuan-Hai Zhang et al.   JOURNAL OF SURGICAL RESEARCH

TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

(2010) Kazuhito Naka et al.   NATURE

Lysophosphatidic acid induces STAT3 phosphorylation and ovarian cancer cell motility: Their inhibition by curcumin

(2009) Ji Hye Seo et al.   CANCER LETTERS

Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways

(2009) Gaoliang Ouyang et al.   CELL BIOLOGY INTERNATIONAL

Tumor Immunotherapy in Melanoma

(2008) Maya Zigler et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-1 (BRCA1) status

(2008) Karedath Abdul Aziz Thasni et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Intracellular cross-talk between the GPCR CXCR1 and CXCR2: Role of carboxyl terminus phosphorylation sites

(2007) Hila Attal et al.   EXPERIMENTAL CELL RESEARCH