Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas

The Angiotensin II Type 1 Receptor Antagonist Losartan Affects NHE1-Dependent Melanoma Cell Behavior

(2018) Daniel Navin Olschewski et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy

(2018) Maria Teresa Di Martino et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy

(2018) Xiudong Guan et al.   Cell Death & Disease

VEGF as a modulator of the innate immune response in glioblastoma

(2017) Kati Turkowski et al.   GLIA

Drug repurposing for the treatment of glioblastoma multiforme

(2017) Claudia Abbruzzese et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion

(2017) Rui Xie et al.   ONCOLOGY REPORTS

Value of pH regulators in the diagnosis, prognosis and treatment of cancer

(2017) Sara Granja et al.   SEMINARS IN CANCER BIOLOGY

Na + /H + exchanger-mediated hydrogen ion extrusion as a carcinogenic signal in triple-negative breast cancer etiopathogenesis and prospects for its inhibition in therapeutics

(2017) Schammim Ray Amith et al.   SEMINARS IN CANCER BIOLOGY

NHE1 has a notable role in metastasis and drug resistance of T-cell acute lymphoblastic leukemia

(2017) Ehtisham Altaf et al.   Oncology Letters

Molecular and clinical characterization of TIM-3 in glioma through 1,024 samples

(2017) Guanzhang Li et al.   OncoImmunology

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

CGCG clinical practice guidelines for the management of adult diffuse gliomas

(2016) Tao Jiang et al.   CANCER LETTERS

Na+/H+exchanger 1, Na+/Ca2+exchanger 1 and calmodulin complex regulates interleukin 6-mediated cellular behavior of human hepatocellular carcinoma

(2016) Jingyu Xu et al.   CARCINOGENESIS

Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+exchanger isoform 1

(2016) Wen Zhu et al.   CARCINOGENESIS

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

(2016) Michele Ceccarelli et al.   CELL

Voltage-gated sodium channel Nav1.7 promotes gastric cancer progression through MACC1-mediated upregulation of NHE1

(2016) Jianling Xia et al.   INTERNATIONAL JOURNAL OF CANCER

The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas

(2016) Hao-Yuan Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The ever-expanding role of HIF in tumour and stromal biology

(2016) Edward L. LaGory et al.   NATURE CELL BIOLOGY

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer

(2016) Caroline Wigerup et al.   PHARMACOLOGY & THERAPEUTICS

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors

(2015) Susan Brandenburg et al.   ACTA NEUROPATHOLOGICA

Ion Transporters in Brain Tumors

(2015) Damin Cong et al.   CURRENT MEDICINAL CHEMISTRY

NHE1 PROMOTE CELL PROLIFERATION IN OVARIAN CANCER: A ROLE OF HYPOXIA-INDUCIBLE FACTORS.

(2015) C. Sanhueza et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice

(2015) Stefano Garofalo et al.   Nature Communications

IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma

(2015) Philipp Kickingereder et al.   Scientific Reports

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

(2015) D. A. Reardon et al.   Cancer Immunology Research

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells

(2015) Gregory J. Baker et al.   Jove-Journal of Visualized Experiments

Combination of an agonistic anti-CD40 monoclonal antibody and the COX-2 inhibitor celecoxib induces anti-glioma effects by promotion of type-1 immunity in myeloid cells and T-cells

(2014) Akemi Kosaka et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H+extrusion, cell migration and survival

(2014) Damin Cong et al.   CARCINOGENESIS

Proton-sensitive cation channels and ion exchangers in ischemic brain injury: New therapeutic targets for stroke?

(2014) Tiandong Leng et al.   PROGRESS IN NEUROBIOLOGY

IDHMutation in Glioma

(2014) Zorbey Turkalp et al.   JAMA Neurology

Lipopolysaccharide-Induced M2 to M1 Macrophage Transformation for IL-12p70 Production Is Blocked by Candida albicans Mediated Up-Regulation of EBI3 Expression

(2013) Xing-Feng Zheng et al.   PLoS One

Molecular classification of gliomas based on whole genome gene expression: a systematic report of 225 samples from the Chinese Glioma Cooperative Group

(2012) Wei Yan et al.   NEURO-ONCOLOGY

Urokinase plasminogen activator receptor induced non-small cell lung cancer invasion and metastasis requires NHE1 transporter expression and transport activity

(2012) J. J. Provost et al.   CELLULAR ONCOLOGY

Annexin A2 Promotes Glioma Cell Invasion and Tumor Progression

(2011) H. Zhai et al.   JOURNAL OF NEUROSCIENCE

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

(2011) Christian M. Metallo et al.   NATURE

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Suppression of NHE1 by small interfering RNA inhibits HIF-1α-induced angiogenesis in vitro via modulation of calpain activity

(2010) Xian-Gang Mo et al.   MICROVASCULAR RESEARCH

Zinc Downregulates HIF-1α and Inhibits Its Activity in Tumor Cells In Vitro and In Vivo

(2010) Lavinia Nardinocchi et al.   PLoS One

Flow cytometry and in vitro analysis of human glioma–associated macrophages

(2009) Ian F. Parney et al.   JOURNAL OF NEUROSURGERY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE