HIF1α-siRNA and gemcitabine combination-based GE-11 peptide antibody-targeted nanomedicine for enhanced therapeutic efficacy in pancreatic cancers

Multimodal selenium nanoshell-capped Au@mSiO2 nanoplatform for NIR-responsive chemo-photothermal therapy against metastatic breast cancer

(2018) Thiruganesh Ramasamy et al.   NPG Asia Materials

Smart chemistry-based nanosized drug delivery systems for systemic applications: A comprehensive review

(2017) Thiruganesh Ramasamy et al.   JOURNAL OF CONTROLLED RELEASE

A phase 3 randomized, double-blind, placebo-controlled trial of ganitumab or placebo in combination with gemcitabine as first-line therapy for metastatic adenocarcinoma of the pancreas: the GAMMA trial†

(2015) C. S. Fuchs et al.   ANNALS OF ONCOLOGY

Co-delivery of HIF1α siRNA and gemcitabine via biocompatible lipid-polymer hybrid nanoparticles for effective treatment of pancreatic cancer

(2015) Xiao Zhao et al.   BIOMATERIALS

Systemic delivery of axitinib with nanohybrid liposomal nanoparticles inhibits hypoxic tumor growth

(2015) Ju Yeon Choi et al.   Journal of Materials Chemistry B

Layer-by-layer assembly of liposomal nanoparticles with PEGylated polyelectrolytes enhances systemic delivery of multiple anticancer drugs

(2014) Thiruganesh Ramasamy et al.   Acta Biomaterialia

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Gemcitabine: Metabolism and molecular mechanisms of action, sensitivity and chemoresistance in pancreatic cancer

(2014) Lucas de Sousa Cavalcante et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of Overcoming Intrinsic Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma through the Redox Modulation

(2014) H.-Q. Ju et al.   MOLECULAR CANCER THERAPEUTICS

Codelivery of VEGF siRNA and Gemcitabine Monophosphate in a Single Nanoparticle Formulation for Effective Treatment of NSCLC

(2013) Yuan Zhang et al.   MOLECULAR THERAPY

Role of epidermal growth factor receptor in breast cancer

(2012) Hiroko Masuda et al.   BREAST CANCER RESEARCH AND TREATMENT

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nanovector delivery of siRNA for cancer therapy

(2012) H Shen et al.   CANCER GENE THERAPY

PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors

(2012) Galith Abourbeh et al.   IUBMB LIFE

Tuning Nanoparticle Uptake: Live-Cell Imaging Reveals Two Distinct Endocytosis Mechanisms Mediated by Natural and Artificial EGFR Targeting Ligand

(2012) Frauke M. Mickler et al.   NANO LETTERS

EGF receptor-targeted nanocarriers for enhanced cancer treatment

(2012) Alyssa M Master et al.   Nanomedicine

Gemcitabine-loaded innovative nanocarriers vs GEMZAR: Biodistribution, pharmacokinetic features andin vivoantitumor activity

(2011) Christian Celia et al.   Expert Opinion on Drug Delivery

Disconnecting the Yin and Yang Relation of Epidermal Growth Factor Receptor (EGFR)-Mediated Delivery: A Fully Synthetic, EGFR-Targeted Gene Transfer System Avoiding Receptor Activation

(2011) A. Schäfer et al.   HUMAN GENE THERAPY

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

siRNA delivery systems for cancer treatment

(2009) Yu-Kyoung Oh et al.   ADVANCED DRUG DELIVERY REVIEWS

Novel Approaches to Deliver Gemcitabine to Cancers

(2008) L. Reddy et al.   CURRENT PHARMACEUTICAL DESIGN