Gemcitabine-loaded innovative nanocarriers vs GEMZAR: Biodistribution, pharmacokinetic features andin vivoantitumor activity

Anticancer Activity of a Broccoli Derivative, Sulforaphane, in Barrett Adenocarcinoma: Potential Use in Chemoprevention and as Adjuvant in Chemotherapy

(2014) Aamer Qazi et al.   Translational Oncology

Resveratrol and cellular mechanisms of cancer prevention

(2011) Yogeshwer Shukla et al.   Annals of the New York Academy of Sciences

CNT1 Expression Influences Proliferation and Chemosensitivity in Drug-Resistant Pancreatic Cancer Cells

(2011) Y. D. Bhutia et al.   CANCER RESEARCH

Drug delivery systems for differential release in combination therapy

(2011) Hongbin Zhang et al.   Expert Opinion on Drug Delivery

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Superior Preclinical Efficacy of Gemcitabine Developed As Chitosan Nanoparticulate System

(2010) José L. Arias et al.   BIOMACROMOLECULES

Folate-targeted supramolecular vesicular aggregates based on polyaspartyl-hydrazide copolymers for the selective delivery of antitumoral drugs

(2010) Mariano Licciardi et al.   BIOMATERIALS

Multi-functional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific chemotherapy

(2010) Kenji Kono et al.   BIOMATERIALS

3-Arylisoquinolines as novel topoisomerase I inhibitors

(2010) Daulat Bikram Khadka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pharmacokinetic study to optimize the intravesical administration of gemcitabine

(2010) Paolo Gontero et al.   BJU INTERNATIONAL

Cisplatin–gemcitabine therapy in metastatic breast cancer: Improved outcome in triple negative breast cancer patients compared to non-triple negative patients

(2010) Nebu Koshy et al.   BREAST

Equilibrative nucleoside transporter 1 genotype, cytidine deaminase activity and age predict gemcitabine plasma clearance in patients with solid tumours

(2010) Milena Gusella et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities

(2010) Chih-Bo Hu et al.   CANCER SCIENCE

Synergistic Cytotoxicity and Molecular Interaction on Drug Targets of Sorafenib and Gemcitabine in Human Pancreas Cancer Cells

(2010) Simona Ricciardi et al.   CHEMOTHERAPY

High Impact of Oatp1a/1b Transporters on In Vivo Disposition of the Hydrophobic Anticancer Drug Paclitaxel

(2010) E. van de Steeg et al.   CLINICAL CANCER RESEARCH

Liposomes as delivery systems for nasal vaccination: strategies and outcomes

(2010) Béatrice Heurtault et al.   Expert Opinion on Drug Delivery

Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: An original drug delivery pathway

(2010) L. Bildstein et al.   JOURNAL OF CONTROLLED RELEASE

Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR®: Biodistribution, pharmacokinetic features and in vivo antitumor activity

(2010) Donatella Paolino et al.   JOURNAL OF CONTROLLED RELEASE

Cetuximab, gemcitabine, and oxaliplatin in patients with unresectable advanced or metastatic biliary tract cancer: a phase 2 study

(2010) Birgit Gruenberger et al.   LANCET ONCOLOGY

Effectiveness of bevacizumab- and pemetrexed-cisplatin treatment for patients with advanced non-squamous non-small cell lung cancer

(2010) Mark Nuijten et al.   LUNG CANCER

Impact of S-1 on the Survival of Patients With Advanced Pancreatic Cancer

(2010) Yousuke Nakai et al.   PANCREAS

Preparation, physicochemical characterization and cytotoxicityin vitroof gemcitabine-loaded PEG-PDLLA nanovesicles

(2010) Lin Jia   WORLD JOURNAL OF GASTROENTEROLOGY

Liposomes as multicompartmental carriers for multidrug delivery in anticancer chemotherapy

(2010) Donato Cosco et al.   Drug Delivery and Translational Research

Preparation of albumin nanospheres loaded with gemcitabine and their cytotoxicity against BXPC-3 cells in vitro

(2009) Jin-ming Li et al.   ACTA PHARMACOLOGICA SINICA

Squalene: A natural triterpene for use in disease management and therapy

(2009) L. Harivardhan Reddy et al.   ADVANCED DRUG DELIVERY REVIEWS

Antitumor effects of polysorbate-80 coated gemcitabine polybutylcyanoacrylate nanoparticles in vitro and its pharmacodynamics in vivo on C6 glioma cells of a brain tumor model

(2009) Chun-Xia Wang et al.   BRAIN RESEARCH

In vivo activity of gemcitabine-loaded PEGylated small unilamellar liposomes against pancreatic cancer

(2009) Donato Cosco et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Expression of nucleoside transporters, deoxycitidine kinase, ribonucleotide reductase regulatory subunits, and gemcitabine catabolic enzymes in primary ovarian cancer

(2009) Gabriella Ferrandina et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Safety, Pharmacokinetics, and Efficacy of CPX-1 Liposome Injection in Patients with Advanced Solid Tumors

(2009) G. Batist et al.   CLINICAL CANCER RESEARCH

Transport of Nucleoside Analogs Across the Plasma Membrane: A Clue to Understanding Drug-Induced Cytotoxicity

(2009) I. Huber-Ruano et al.   CURRENT DRUG METABOLISM

Freeze-drying of squalenoylated nucleoside analogue nanoparticles

(2009) L. Bildstein et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II

(2009) Ahad A. Sadiq et al.   INVESTIGATIONAL NEW DRUGS

Antitumor activity of EGFR targeted pH-sensitive immunoliposomes encapsulating gemcitabine in A549 xenograft nude mice

(2009) In-Young Kim et al.   JOURNAL OF CONTROLLED RELEASE

Rapid and sustained response of an intra- and extracranial large cell lymphoma mass to liposomal intrathecal Ara-C and R-MegaCEOP systemic chemotherapy

(2009) Lorenzo Falchi et al.   JOURNAL OF NEURO-ONCOLOGY

Drug ratio-dependent antitumor activity of irinotecan and cisplatin combinations in vitro and in vivo

(2009) P. G. Tardi et al.   MOLECULAR CANCER THERAPEUTICS

Anticancer Efficacy of Squalenoyl Gemcitabine Nanomedicine on 60 Human Tumor Cell Panel and on Experimental Tumor

(2009) L. Harivardhan Reddy et al.   MOLECULAR PHARMACEUTICS

A novel animal model to evaluate the ability of a drug delivery system to promote the passage through the BBB

(2009) Michelangelo Iannone et al.   NEUROSCIENCE LETTERS

Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer

(2008) Sandra Pérez-Torras et al.   BIOCHEMICAL PHARMACOLOGY

Polyaspartylhydrazide Copolymer-Based Supramolecular Vesicular Aggregates as Delivery Devices for Anticancer Drugs

(2008) D. Paolino et al.   BIOMACROMOLECULES

Novel Approaches to Deliver Gemcitabine to Cancers

(2008) L. Reddy et al.   CURRENT PHARMACEUTICAL DESIGN

Squalenoylation Favorably Modifies the in Vivo Pharmacokinetics and Biodistribution of Gemcitabine in Mice

(2008) L. H. Reddy et al.   DRUG METABOLISM AND DISPOSITION

Colloidal carriers for the enhanced delivery through the skin

(2008) D Cosco et al.   Expert Opinion on Drug Delivery

Gemcitabine: vascular toxicity and prothrombotic potential

(2008) Constantin A Dasanu   Expert Opinion On Drug Safety

Gemcitabine Plus Paclitaxel Versus Paclitaxel Monotherapy in Patients With Metastatic Breast Cancer and Prior Anthracycline Treatment

(2008) Kathy S. Albain et al.   JOURNAL OF CLINICAL ONCOLOGY

Antitumoral activity of PEG–gemcitabine prodrugs targeted by folic acid

(2008) Gianfranco Pasut et al.   JOURNAL OF CONTROLLED RELEASE

Improved In Vitro Anti-Tumoral Activity, Intracellular Uptake and Apoptotic Induction of Gemcitabine-Loaded Pegylated Unilamellar Liposomes

(2008) Christian Celia et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Preclinical Toxicology (Subacute and Acute) and Efficacy of a New Squalenoyl Gemcitabine Anticancer Nanomedicine

(2008) L. H. Reddy et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Influence of the Macromolecular Architecture on the Self-Assembly of Amphiphilic Copolymers Based on Poly(N,N-dimethylamino-2-ethyl methacrylate) and Poly(ε-caprolactone)

(2008) F. Bougard et al.   LANGMUIR

Liposomal delivery improves the growth-inhibitory and apoptotic activity of low doses of gemcitabine in multiple myeloma cancer cells

(2008) Christian Celia et al.   Nanomedicine-Nanotechnology Biology and Medicine

Discovery of New Hexagonal Supramolecular Nanostructures Formed by Squalenoylation of an Anticancer Nucleoside Analogue

(2008) Patrick Couvreur et al.   Small