An Adiponectin Receptor Agonist Reduces Type 2 Diabetic Periodontitis

The Adiponectin Receptor Agonist AdipoRon Ameliorates Diabetic Nephropathy in a Model of Type 2 Diabetes

(2018) Yaeni Kim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Overexpression of MiR-335-5p Promotes Bone Formation and Regeneration in Mice

(2017) Lan Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Scientific evidence on the links between periodontal diseases and diabetes: Consensus report and guidelines of the joint workshop on periodontal diseases and diabetes by the International Diabetes Federation and the European Federation of Periodontology

(2017) Mariano Sanz et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes

(2017) David Polak et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

MicroRNA-126 Regulates Inflammatory Cytokine Secretion in Human Gingival Fibroblasts Under High Glucose via Targeting Tumor Necrosis Factor Receptor Associated Factor 6

(2017) Yi Wu et al.   JOURNAL OF PERIODONTOLOGY

Adiponectin regulates BMSC osteogenic differentiation and osteogenesis through the Wnt/β-catenin pathway

(2017) Yiyao Wang et al.   Scientific Reports

Dietary Uncoupling of Gut Microbiota and Energy Harvesting from Obesity and Glucose Tolerance in Mice

(2017) Matthew J. Dalby et al.   Cell Reports

Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism

(2017) Jin Zhang et al.   Bone Research

Therapeutic Targets for Management of Periodontitis and Diabetes

(2016) Corneliu Sima et al.   CURRENT PHARMACEUTICAL DESIGN

Adiponectin Promotes Human Jaw Bone Marrow Stem Cell Osteogenesis

(2016) Y. Pu et al.   JOURNAL OF DENTAL RESEARCH

Adipokines in bone disease

(2016) Elena Neumann et al.   Nature Reviews Rheumatology

AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings

(2015) Yanqing Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adiponectin enhances osteogenic differentiation in human adipose-derived stem cells by activating the APPL1-AMPK signaling pathway

(2015) Tong Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Central adiponectin administration reveals new regulatory mechanisms of bone metabolism in mice

(2014) Yuwei Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adiponectin Ameliorates Experimental Periodontitis in Diet-Induced Obesity Mice

(2014) Lan Zhang et al.   PLoS One

Adiponectin Regulates Bone Marrow Mesenchymal Stem Cell Niche Through a Unique Signal Transduction Pathway: An Approach for Treating Bone Disease in Diabetes

(2014) Liming Yu et al.   STEM CELLS

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

(2013) Miki Okada-Iwabu et al.   NATURE

Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1–31)NH2] in postmenopausal women with osteoporosis

(2012) K. Henriksen et al.   BONE

Diabetes Impairs Stem Cell and Proangiogenic Cell Mobilization in Humans

(2012) G. P. Fadini et al.   DIABETES CARE

Prevalence of Periodontitis in Adults in the United States: 2009 and 2010

(2012) P.I. Eke et al.   JOURNAL OF DENTAL RESEARCH

Local and Circulating Levels of Adipocytokines in Obese and Normal Weight Individuals With Chronic Periodontitis

(2012) Glaucia Santos Zimmermann et al.   JOURNAL OF PERIODONTOLOGY

Bone, sweet bone—osteoporotic fractures in diabetes mellitus

(2012) Christine Hamann et al.   Nature Reviews Endocrinology

Intermittent Administration of Human Parathyroid Hormone before Osteosynthesis Stimulates Cancellous Bone Union in Ovariectomized Rats

(2012) Hiroyuki Tsuchie et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Periodontitis and diabetes: a two-way relationship

(2011) P. M. Preshaw et al.   DIABETOLOGIA

Adiponectin Inhibits Osteoclastogenesis and Bone Resorption via APPL1-mediated Suppression of Akt1

(2011) Qisheng Tu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relationships Among Interleukin-6, Tumor Necrosis Factor-α, Adipokines, Vitamin D, and Chronic Periodontitis

(2011) Flavia R. Teles et al.   JOURNAL OF PERIODONTOLOGY

Diabetic Stem-Cell “Mobilopathy”

(2011) John F. DiPersio   NEW ENGLAND JOURNAL OF MEDICINE

Periodontal treatment with topical antibiotics improves glycemic control in association with elevated serum adiponectin in patients with type 2 diabetes mellitus

(2011) Pariksha Bharti et al.   Obesity Research & Clinical Practice

Malfunction of bone marrow-derived osteoclasts and the delay of bone fracture healing in diabetic mice

(2010) Toshiyuki Kasahara et al.   BONE

Intermittent Parathyroid Hormone Administration Counteracts the Adverse Effects of Glucocorticoids on Osteoblast and Osteocyte Viability, Bone Formation, and Strength in Mice

(2010) Robert S. Weinstein et al.   ENDOCRINOLOGY

Inflammation and Uncoupling as Mechanisms of Periodontal Bone Loss

(2010) D.T. Graves et al.   JOURNAL OF DENTAL RESEARCH

Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model

(2009) Toshiyuki Kitaori et al.   ARTHRITIS AND RHEUMATISM

Pharmacotherapies to Manage Bone Loss-Associated Diseases: A Quest for the Perfect Benefit-to-Risk Ratio

(2008) P. Valverde   CURRENT MEDICINAL CHEMISTRY

Haploinsufficiency ofRunx2results in bone formation decrease and different BSP expression pattern changes in two transgenic mouse models

(2008) Qisheng Tu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Circulating Bone Marrow-Derived Osteoblast Progenitor Cells Are Recruited to the Bone-Forming Site by the CXCR4/Stromal Cell-Derived Factor-1 Pathway

(2007) Satoru Otsuru et al.   STEM CELLS