Article
Chemistry, Analytical
M. A. Kochetkova, I. I. Timofeeva, A. V. Bulatov
Summary: A method of dispersive liquid-liquid microextraction based on the evaporation of a highly volatile nonpolar organic solvent is developed. The method exhibits analytical capabilities in determining preservatives in soft drinks for baby food using high-performance liquid chromatography. The use of a terpenoid and a highly volatile organochlorine solvent as the extractant and dispersant allows for the exclusion of polar organic solvents, reducing the distribution coefficients. The method does not require centrifugation for phase separation.
JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Orhan Destanoglu
Summary: A HS-GC-MS method was developed for simultaneous determination of benzoic acid (BA) and sorbic acid (SoA) in non-alcoholic beverages. The method provided sensitive and reliable results with minimal reagent and sample consumption. Derivatization of BA, SoA, and internal standard Salicylic acid (SalA) to their methyl esters was necessary for HS-GC-MS measurement. Extensive optimization studies were performed for in-vial derivatization. The validated method demonstrated high precision and accuracy for BA and SoA analysis in beverage samples.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2023)
Article
Chemistry, Analytical
Valfredo Azevedo Lemos, Jeferson Alves Barreto, Luana Bastos Santos, Rosivan dos Santos de Assis, Cleber Galvao Novaes, Ricardo J. Cassella
Summary: Dispersive liquid-liquid microextraction (DLLME) is widely used for the separation and preconcentration of various chemical species, with some systems using a syringe as an extraction environment. This review discusses methods utilizing this approach, critical aspects like dispersion promotion, analytical characteristics, and the pros and cons of the methods, as well as future trends in in-syringe microextraction systems.
Article
Chemistry, Applied
J. A. Custodio-Mendoza, C. Caamano-Fernandez, M. A. Lage, P. J. Almeida, R. A. Lorenzo, A. M. Carro
Summary: A new, fast, simple, and effective UA-DLLME method was successfully developed and validated for the determination of malondialdehyde, acrolein, and 4-hydroxy-2-nonenal in beverages. The method demonstrated good linearities, recoveries, and reproducibility, and was applied to analyze 60 different beverage samples, showing the presence of secondary lipid oxidation products.
Article
Biochemical Research Methods
Inas A. Abdallah, Sherin F. Hammad, Alaa Bedair, Mohamed A. Abdelaziz, Neil D. Danielson, Ahmed H. Elshafeey, Fotouh R. Mansour
Summary: In this study, a gadolinium-based magnetic ionic liquid was used as an extractant to determine favipiravir in human plasma using dispersive liquid-liquid microextraction (DLLME) and HPLC/UV. The method was validated to be simple, selective, and sensitive for the determination of favipiravir in real samples.
BIOMEDICAL CHROMATOGRAPHY
(2022)
Article
Food Science & Technology
Bochra Bejaoui Kefi, Sana Baccouri, Rachel Torkhani, Sidrine Koumba, Patrick Martin, Naceur M'Hamdi
Summary: This study optimized the extraction process of two preservatives in food drinks using an experimental design. A simple and reliable solid-phase extraction method was proposed for the simultaneous extraction and determination of these preservatives. The optimized conditions were successfully applied to commercial fruit juices and soft drinks, showing minimal matrix effect.
Article
Chemistry, Analytical
Adil Elik, Handan Sarac, Hasan Durukan, Ahmet Demirbas, Nail Altunay
Summary: A vortex assisted magnetic ionic liquid based dispersive liquid-liquid microextraction method was developed for the determination and extraction of metribuzin in plant samples using a tetrachloromanganate-based magnetic ionic liquid as the extraction solvent. The optimized method showed low detection limit, good linearity, and was successfully applied for extraction and determination of metribuzin in plant samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Heike Denghel, Thomas Goeen
Summary: UV 328 is a benzotriazole ultraviolet light absorber used in plastics and other organic substances. A new analytical method has been developed to determine UV 328 and its metabolites in human whole blood.
Article
Chemistry, Applied
David Baute-Perez, Alvaro Santana-Mayor, Antonio Herrera-Herrera, Barbara Socas-Rodriguez, Miguel Angel Rodriguez-Delgado
Summary: This study conducted the analysis of alkylphenols, bisphenols, and alkylphenol ethoxylates in bottled waters, kombuchas, and water kefir using a vortex-assisted dispersive liquid-liquid microextraction method with a natural hydrophobic eutectic solvent. The method was validated for matrix effect, linearity, limits of detection, and recovery, showing promising results for the extraction of these compounds in different beverages. The study also detected specific contaminants in the analyzed samples, providing valuable insights for future research in this area.
Article
Chemistry, Multidisciplinary
Chiara Dal Bosco, Valerio Di Lisio, Paola D'Angelo, Alessandra Gentili
Summary: An ideal hydrophobic eutectic solvent based on L-menthol and butylated hydroxytoluene in a molar ratio of 3:1 was proposed and confirmed through physicochemical characterization. It showed intrinsic antioxidant activity and was efficient in extracting and preserving easily oxidizable lipophilic compounds. The solvent was successfully utilized for the dispersive liquid-liquid microextraction of carotenoids and fat-soluble vitamins from fruit juices.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Chemistry, Analytical
Asmaa Kamal El-Deen, Heba Elmansi, Kuniyoshi Shimizu
Summary: A green vortex-assisted dispersive liquid-liquid microextraction (VA-DLLME) method based on a hydrophobic natural deep eutectic solvent (NaDES) was developed and applied for the preconcentration of anti-prostate cancer triple therapy (flutamide, resveratrol, and ethynylestradiol) from river water and spiked human plasma for the first time. The optimal extraction conditions were determined through a systematic methodology and the method exhibited excellent linearity and precision.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Mustafa Tuzen, Adil Elik, Nail Altunay
Summary: A simple, sensitive, selective and green ultrasound-assisted supramolecular solvent dispersive liquid-liquid microextraction (UA-SUPRAS-DLLME) method was developed for preconcentration and determination of chromium ions in various samples. By optimizing various parameters, high extraction efficiency and accuracy were achieved.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Multidisciplinary
Malek Hassan, Furkan Uzcan, Syed Nasrullah Shah, Usama Alshana, Mustafa Soylak
Summary: The combination of switchable-hydrophilicity solvent-liquid-liquid microextraction (SHS-LLME) and dispersive solid-phase microextraction (DSPME) showed efficient preconcentration and determination of quercetin, with high recovery rates and good repeatability. The proposed method is superior in terms of greenness, rapidness, simplicity, and low capital cost, making it a promising technique for sample cleanup and analysis.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2021)
Article
Chemistry, Multidisciplinary
Qian Liu, Zhiqiang Li, Liulin Wei, Xiaomei Chen, Yidong Xu, Jingchan Zhao
Summary: In this study, a thermo-switchable deep eutectic solvent was used to improve the extraction of organophosphorus pesticides and pyrethroids in water samples. The method showed fast extraction, high precision, and low detection limit.
ENVIRONMENTAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Analytical
Maliheh Heidarbeigi, Mohammad T. Jafari, Mohammad Saraji
Summary: The study utilized a tandem microextraction method combining centrifuge free dispersive liquid-liquid microextraction and thin-film microextraction for the analysis of molinate in environmental samples, achieving high detection sensitivity and accuracy under optimized conditions. This approach offers a feasible method for the determination of molinate in real samples, with the recovery of spiked samples ranging between 82% and 113%.
Article
Biochemical Research Methods
Irina Timofeeva, Dania Kanashina, Leonid Moskvin, Andrey Bulatov
JOURNAL OF CHROMATOGRAPHY A
(2017)
Article
Chemistry, Physical
Irina Timofeeva, Dania Kanashina, Dmitry Kirsanov, Andrey Bulatov
JOURNAL OF MOLECULAR LIQUIDS
(2018)
Article
Chemistry, Analytical
Irina I. Timofeeva, Christina S. Vakh, Andrey V. Bulatov, Paul J. Worsfold
Article
Chemistry, Analytical
Yu. Malinina, M. Ya. Kamentsev, I. I. Timofeeva, L. N. Moskvin, N. M. Yakimova, I. D. Kuchumova
JOURNAL OF ANALYTICAL CHEMISTRY
(2019)
Review
Chemistry, Analytical
K. S. Vakh, I. I. Timofeeva, A. V. Bulatov
JOURNAL OF ANALYTICAL CHEMISTRY
(2019)
Article
Chemistry, Physical
Daria Kanashina, Aleksei Pochivalov, Irina Timofeeva, Andrey Bulatov
JOURNAL OF MOLECULAR LIQUIDS
(2020)
Article
Chemistry, Applied
Irina Timofeeva, Kira Stepanova, Andrey Shishov, Lawrence Nugbienyo, Leonid Moskvin, Andrey Bulatov
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2020)
Article
Chemistry, Analytical
Irina Timofeeva, Kira Stepanova, Andrey Bulatov
Summary: The new automated microextraction method demonstrated efficient extraction of polycyclic aromatic hydrocarbons in tea infusion with fast sample processing speed and no need for centrifugation.
Article
Spectroscopy
Irina Timofeeva, Polina Davletbaeva, Alexey Moskvin, Andrey Bulatov
Summary: A chemosensor was developed and applied for on-site sensing of ammonia precursor in concrete, effectively preventing ammonia emission into indoor space. The sensor showed excellent selectivity and sensitivity, with a visual detection limit of 15 mg kg-1 for urea. Builders successfully used the sensor on different construction sites to quickly detect ammonia precursors in concrete.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Kirill Barbayanov, Irina Timofeeva, Andrey Bulatov
Summary: An effervescence-assisted dispersive liquid-liquid microextraction approach using a three-component deep eutectic solvent has been developed for the determination of fluoroquinolone antibiotics in foods. The proposed method showed higher extraction efficiency compared to individual hydrophobic precursors and provided effective dispersion of the extractant, speeding up the extraction process.
Article
Chemistry, Multidisciplinary
Irina Timofeeva, Mariya Alikina, Mikhail Osmolowsky, Olga Osmolovskaya, Andrey Bulatov
NEW JOURNAL OF CHEMISTRY
(2020)
Article
Chemistry, Analytical
Irina Timofeeva, Mariya Alikina, Anna Vlasova, Mikhail Osmolowsky, Mikhail Voznesenskiy, Olga Volina, Leonid Moskvin, Olga Osmolovskaya, Andrey Bulatov
Article
Chemistry, Analytical
Aleksei Pochivalov, Irina Timofeeva, Christina Vakh, Andrey Bulatov
ANALYTICA CHIMICA ACTA
(2017)
Article
Chemistry, Analytical
Irina Timofeeva, Semen Timofeev, Leonid Moskvin, Andrey Bulatov
ANALYTICA CHIMICA ACTA
(2017)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)