AdoMet triggers apoptosis in head and neck squamous cancer by inducing ER stress and potentiates cell sensitivity to cisplatin

Cisplatin based therapy: the role of the mitogen activated protein kinase signaling pathway

(2018) Iman W. Achkar et al.   Journal of Translational Medicine

Pro-oxidant and pro-apoptotic activity of polyphenol extract from Annurca apple and its underlying mechanisms in human breast cancer cells

(2017) Stefania D'Angelo et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

S-Adenosylmethionine-mediated apoptosis is potentiated by autophagy inhibition induced by chloroquine in human breast cancer cells

(2017) Donatella Delle Cave et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate

(2017) Marco Corazzari et al.   Frontiers in Oncology

Folates and S-Adenosylmethionine for Major Depressive Disorder

(2017) George I Papakostas et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

miR-125b-5p enhances chemotherapy sensitivity to cisplatin by down-regulating Bcl2 in gallbladder cancer

(2017) Dong Yang et al.   Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53

(2016) Valentina Pagliara et al.   Oncotarget

Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway

(2016) Akio Tsuru et al.   Scientific Reports

Biochemical Characterization of a Thermostable Adenosylmethionine Synthetase from the Archaeon Pyrococcus Furiosus with High Catalytic Power

(2015) Marina Porcelli et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

S-Adenosylmethionine Affects ERK1/2 and Stat3 Pathways and Induces Apotosis in Osteosarcoma Cells

(2015) Concetta Paola Ilisso et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines

(2015) PUTERI BAHARUDDIN et al.   ONCOLOGY REPORTS

S-adenosylmethionine blocks osteosarcoma cells proliferation and invasionin vitroand tumor metastasisin vivo: therapeutic and diagnostic clinical applications

(2015) Surabhi Parashar et al.   Cancer Medicine

A thermostable archaealS-adenosylmethionine synthetase: a promising tool to improve the synthesis of adenosylmethionine analogs of biotechnological interest

(2015) Marina Porcelli et al.   Bioengineered

New insights into the roles of CHOP-induced apoptosis in ER stress

(2014) Yiming Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

(2014) Nicola J. Darling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Synergistic anti-breast cancer effect of a combined treatment with the methyl donorS-adenosyl methionine and the DNA methylation inhibitor 5-aza-2′-deoxycytidine

(2013) Flora Chik et al.   CARCINOGENESIS

Use of LysoTracker dyes: A flow cytometric study of autophagy

(2013) Shaheen Chikte et al.   CYTOMETRY PART A

S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer

(2013) Z. Hussain et al.   GENETICS AND MOLECULAR RESEARCH

Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis

(2013) Maddalena Frau et al.   JOURNAL OF HEPATOLOGY

S-Adenosylmethionine Inhibits the Growth of Cancer Cells by Reversing the Hypomethylation Status of c-myc and H-ras in Human Gastric Cancer and Colon Cancer

(2012) Jin Luo et al.   International Journal of Biological Sciences

S-adenosylmethionine (SAMe) therapy in liver disease: A review of current evidence and clinical utility

(2012) Quentin M. Anstee et al.   JOURNAL OF HEPATOLOGY

Inhibitory effect of S-adenosylmethionine on the growth of human gastric cancer cells in vivo and in vitro

(2012) Ye Zhao et al.   Chinese Journal of Cancer

c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

(2011) Ting Sun et al.   Journal of Translational Medicine

BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received

(2010) S-J Dawson et al.   BRITISH JOURNAL OF CANCER

Ablation of C/EBP Homologous Protein Attenuates Endoplasmic Reticulum–Mediated Apoptosis and Cardiac Dysfunction Induced by Pressure Overload

(2010) Hai Ying Fu et al.   CIRCULATION

Emerging Bcl-2 inhibitors for the treatment of cancer

(2010) Asfar S Azmi et al.   EXPERT OPINION ON EMERGING DRUGS

S-Adenosylmethionine and Methylthioadenosine Inhibit Cellular FLICE Inhibitory Protein Expression and Induce Apoptosis in Colon Cancer Cells

(2009) T. W. H. Li et al.   MOLECULAR PHARMACOLOGY