Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling

Efficacy of Ranolazine in Patients With Symptomatic Hypertrophic Cardiomyopathy

(2018) Iacopo Olivotto et al.   Circulation-Heart Failure

Elevated local [Ca2+] and CaMKII promote spontaneous Ca2+release in ankyrin-B-deficient hearts

(2016) Iuliana Popescu et al.   CARDIOVASCULAR RESEARCH

Long-term administration of ranolazine attenuates diastolic dysfunction and adverse myocardial remodeling in a model of heart failure with preserved ejection fraction

(2016) Antonella De Angelis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cell cycle and apoptosis regulation by NFAT transcription factors: new roles for an old player

(2016) G P Mognol et al.   Cell Death & Disease

Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effectsin vivoin a mouse model of hypertrophic cardiomyopathy

(2015) Frederik Flenner et al.   CARDIOVASCULAR RESEARCH

Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII

(2015) Thomas H. Fischer et al.   CARDIOVASCULAR RESEARCH

Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In VivoCLINICAL PERSPECTIVE

(2015) Patric Glynn et al.   CIRCULATION

Diltiazem Treatment for Pre-Clinical Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers

(2015) Carolyn Y. Ho et al.   JACC-Heart Failure

Ranolazine improves diastolic function in spontaneously hypertensive rats

(2014) Sarah Williams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertension

(2014) Marcella Rocchetti et al.   CARDIOVASCULAR RESEARCH

Treatment for calcium channel blocker poisoning: A systematic review

(2014) M. St-Onge et al.   CLINICAL TOXICOLOGY

Ca 2+ /Calmodulin-Dependent Protein Kinase II and Protein Kinase A Differentially Regulate Sarcoplasmic Reticulum Ca 2+ Leak in Human Cardiac Pathology

(2013) Thomas H. Fischer et al.   CIRCULATION

Ca2+ Fluxes Involvement in Gene Expression During Cardiac Hypertrophy

(2013) Ana Gomez et al.   Current Vascular Pharmacology

Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease

(2013) Karl Toischer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Coping with Endoplasmic Reticulum Stress in the Cardiovascular System

(2012) Jody Groenendyk et al.   Annual Review of Physiology

Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy

(2012) Raffaele Coppini et al.   CIRCULATION

Ranolazine stabilizes cardiac ryanodine receptors: A novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2

(2012) Ashish Parikh et al.   HEART RHYTHM

Functional Cross-Talk Between Aldosterone and Angiotensin-(1-7) in Ventricular Myocytes

(2012) Pedro W. Machado de Almeida et al.   HYPERTENSION

Impaired left ventricular systolic function reserve limits cardiac output and exercise capacity in HFpEF patients due to systemic hypertension

(2012) Michael Henein et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

MFEprimer-2.0: a fast thermodynamics-based program for checking PCR primer specificity

(2012) Wubin Qu et al.   NUCLEIC ACIDS RESEARCH

Role of ranolazine in angina, heart failure, arrhythmias, and diabetes

(2011) Samuel Sossalla et al.   PHARMACOLOGY & THERAPEUTICS

β-AR Blockers Suppresses ER Stress in Cardiac Hypertrophy and Heart Failure

(2011) Li Ni et al.   PLoS One

Improvement in Left Ventricular Systolic and Diastolic Performance During Ranolazine Treatment in Patients With Stable Angina

(2010) Vincent M. Figueredo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

B-Type Natriuretic Peptide and the Effect of Ranolazine in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes

(2010) David A. Morrow et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Transverse Aortic Constriction in Mice

(2010) Angela C. deAlmeida et al.   Jove-Journal of Visualized Experiments

Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure

(2008) Sharad Rastogi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY