MT1-MMP downregulation via the PI3K/Akt signaling pathway is required for the mechanical stretching-inhibited invasion of bone-marrow-derived mesenchymal stem cells

Decreased nuclear stiffness via FAK-ERK1/2 signaling is necessary for osteopontin-promoted migration of bone marrow-derived mesenchymal stem cells

(2017) Lingling Liu et al.   EXPERIMENTAL CELL RESEARCH

PI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment

(2016) Angel Guerrero-Zotano et al.   CANCER AND METASTASIS REVIEWS

Improving Stem Cell Therapeutics with Mechanobiology

(2016) Jae-Won Shin et al.   Cell Stem Cell

Mechanical stretch enhances the expression and activity of osteopontin and MMP-2 via the Akt1/AP-1 pathways in VSMC

(2015) Kyo Won Seo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

New strategies for targeting matrix metalloproteinases

(2015) Gregg B. Fields   MATRIX BIOLOGY

Membrane-type matrix metalloproteinases: Their functions and regulations

(2015) Yoshifumi Itoh   MATRIX BIOLOGY

Cyclic mechanical stretching promotes migration but inhibits invasion of rat bone marrow stromal cells

(2015) Bingyu Zhang et al.   Stem Cell Research

Leptin-Promoted Human Extravillous Trophoblast Invasion Is MMP14 Dependent and Requires the Cross Talk Between Notch1 and PI3K/Akt Signaling1

(2014) Huayang Wang et al.   BIOLOGY OF REPRODUCTION

PDGF-BB-induced MT1-MMP expression regulates proliferation and invasion of mesenchymal stem cells in 3-dimensional collagen via MEK/ERK1/2 and PI3K/AKT signaling

(2013) Xiaojiao Sun et al.   CELLULAR SIGNALLING

Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin

(2013) Shuang-Bai Zhou et al.   STEM CELLS

Low-Level Shear Stress Induces Human Mesenchymal Stem Cell Migration Through the SDF-1/CXCR4 Axis Via MAPK Signaling Pathways

(2013) Lin Yuan et al.   STEM CELLS AND DEVELOPMENT

Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation

(2012) Hyeong-Il Kwak et al.   ANGIOGENESIS

Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death

(2012) H. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysophosphatidic Acid Induces Migration of Human Lung-Resident Mesenchymal Stem Cells Through the β-Catenin Pathway

(2012) Linda Badri et al.   STEM CELLS

Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression

(2011) Aneta Kwiatkowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

RhoA/ROCK, cytoskeletal dynamics, and focal adhesion kinase are required for mechanical stretch-induced tenogenic differentiation of human mesenchymal stem cells

(2011) Baiyao Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling

(2011) Amit Prasad et al.   NATURE IMMUNOLOGY

Stem Cells Genetically Modified With the Developmental Gene MT1-MMP Improve Regeneration of the Supraspinatus Tendon-to-Bone Insertion Site

(2010) Lawrence V. Gulotta et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Stem cell homing in musculoskeletal injury

(2010) Eliza L.S. Fong et al.   BIOMATERIALS

Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

(2010) Anutosh Chakraborty et al.   CELL

Stem cell homing and angiomyogenesis in transplanted hearts are enhanced by combined intramyocardial SDF-1α delivery and endogenous cytokine signaling

(2009) Tiemin Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy

(2009) Alex Y. Strongin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MT1-MMP controls human mesenchymal stem cell trafficking and differentiation

(2009) C. Lu et al.   BLOOD

Mesenchymal Stem Cell Homing Capacity

(2009) Valeria Sordi   TRANSPLANTATION

Breaching the basement membrane: who, when and how?

(2008) R. Grant Rowe et al.   TRENDS IN CELL BIOLOGY