MicroRNA-590-3P suppresses cell survival and triggers breast cancer cell apoptosis via targeting sirtuin-1 and deacetylation of p53

ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer

(2018) Qiong Song et al.   BMC CANCER

Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma

(2018) Silvia Di Agostino et al.   Theranostics

UCA1 promotes cell proliferation and invasion of gastric cancer by targeting CREB1 sponging to miR-590-3p

(2018) Lei Gu et al.   Cancer Medicine

Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells

(2017) Mohammad Alaee et al.   Journal of Breast Cancer

MiR-590-3p suppresses hepatocellular carcinoma growth by targeting TEAD1

(2017) Xin Ge et al.   TUMOR BIOLOGY

MicroRNA-22 inhibits cell growth and metastasis in breast cancer via targeting of SIRT1

(2017) Quanqing Zou et al.   Experimental and Therapeutic Medicine

MiR-590-3p suppresses epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma by inhibiting SIP1 expression

(2017) Chao Zu et al.   Oncotarget

miR-543 promotes gastric cancer cell proliferation by targeting SIRT1

(2016) Juan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Concurrent acetylation of FoxO1/3a and p53 due to sirtuins inhibition elicit Bim/PUMA mediated mitochondrial dysfunction and apoptosis in berberine-treated HepG2 cells

(2016) Shatrunajay Shukla et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

miR-590-3p suppresses cancer cell migration, invasion and epithelial–mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2

(2015) Hengyuan Pang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A feedback expression of microRNA-590 and activating transcription factor-3 in human breast cancer cells

(2015) P.J. Miranda et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death

(2015) Natascia Guida et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer

(2015) M F Santolla et al.   Cell Death & Disease

Dysregulation of the miR-34a-SIRT1 axis inhibits breast cancer stemness

(2015) Wei Ma et al.   Oncotarget

MicroRNA-212 negatively regulates starvation induced autophagy in prostate cancer cells by inhibiting SIRT1 and is a modulator of angiogenesis and cellular senescence

(2015) Malathi Ramalinga et al.   Oncotarget

MicroRNAs Inhibit the Translation of Target mRNAs on the Endoplasmic Reticulum in Arabidopsis

(2013) Shengben Li et al.   CELL

Redox-regulating sirtuins in aging, caloric restriction, and exercise

(2013) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration

(2013) M Saxena et al.   ONCOGENE

Sorting out functions of sirtuins in cancer

(2013) M Roth et al.   ONCOGENE

SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein

(2013) SHOU-JEN KUO et al.   ONCOLOGY REPORTS

Roles of mitochondrial transcription factor A and microRNA-590-3p in the development of bladder cancer

(2013) MIAO MO et al.   Oncology Letters

SIRT1, Is It a Tumor Promoter or Tumor Suppressor?

(2012) Chu-Xia Deng   International Journal of Biological Sciences

SIRT1 Is Essential for Oncogenic Signaling by Estrogen/Estrogen Receptor   in Breast Cancer

(2011) S. Elangovan et al.   CANCER RESEARCH

Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment

(2011) Tony Peled et al.   EXPERIMENTAL HEMATOLOGY

Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells

(2010) Arunasree M. Kalle et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma

(2010) Ho Lee et al.   HUMAN PATHOLOGY

SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2

(2010) Barrie Peck et al.   MOLECULAR CANCER THERAPEUTICS

A dictionary on microRNAs and their putative target pathways

(2010) Christina Backes et al.   NUCLEIC ACIDS RESEARCH

The Critical Role of the Class III Histone Deacetylase SIRT1 in Cancer

(2009) T. Liu et al.   CANCER RESEARCH

The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors

(2009) Ahmed Essaghir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY