Activation of mammalian terget of rapamycin kinase and glycogen synthase kinase-3β accompanies abnormal accumulation of cholesterol in fibroblasts from Niemann-Pick type C patients

Mitochondrial dysfunction in fibroblasts derived from patients with Niemann-Pick type C disease

(2016) Marcin Woś et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Sensing and responding to energetic stress: The role of the AMPK-PGC1α-NRF1 axis in control of mitochondrial biogenesis in fish

(2016) K. Bremer et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Activation of AMPK α2 inhibits airway smooth muscle cells proliferation

(2016) Lu Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of Liver Metabolism by Autophagy

(2016) Julio Madrigal-Matute et al.   GASTROENTEROLOGY

Regulation of Mitochondrial Biogenesis and Its Intersection with Inflammatory Responses

(2015) Anne D. Cherry et al.   ANTIOXIDANTS & REDOX SIGNALING

Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α pathway

(2015) Kunqian Ji et al.   FREE RADICAL BIOLOGY AND MEDICINE

mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells

(2015) Serguei A. Gordeev et al.   Oncotarget

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

(2014) Yijiao Xu et al.   CELLULAR SIGNALLING

Adaptations of Energy Metabolism Associated with Increased Levels of Mitochondrial Cholesterol in Niemann-Pick Type C1-deficient Cells

(2014) Barry E. Kennedy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum-associated Degradation of Niemann-Pick C1

(2014) Naoe Nakasone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Where is mTOR and what is it doing there?

(2014) Charles Betz et al.   JOURNAL OF CELL BIOLOGY

Lysosome: regulator of lipid degradation pathways

(2014) Carmine Settembre et al.   TRENDS IN CELL BIOLOGY

Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α

(2013) Yi Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade

(2013) Mingo Ming Ho Yung et al.   BMC CANCER

Interaction of AnxA6 with isolated and artificial lipid microdomains; importance of lipid composition and calcium content

(2013) Magdalena M. Domon et al.   Molecular BioSystems

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pre-Symptomatic Activation of Antioxidant Responses and Alterations in Glucose and Pyruvate Metabolism in Niemann-Pick Type C1-Deficient Murine Brain

(2013) Barry E. Kennedy et al.   PLoS One

Phosphoinositide 3-Kinase   Inhibits Cardiac GSK-3 Independently of Akt

(2013) M. L. Mohan et al.   Science Signaling

Glycogen synthase kinase-3β regulates anti-inflammatory property of fluoxetine

(2012) Hui-Chen Su et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dual Regulation of Glycogen Synthase Kinase 3 (GSK3)α/β by Protein Kinase C (PKC)α and Akt Promotes Thrombin-mediated Integrin αIIbβ3Activation and Granule Secretion in Platelets

(2012) Samantha F. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Niemann-Pick Type C2 protein contributes to the transport of endosomal cholesterol to mitochondria without interacting with NPC1

(2012) Barry E. Kennedy et al.   JOURNAL OF LIPID RESEARCH

Impaired dynamics of the late endosome/lysosome compartment in human Niemann–Pick type C skin fibroblasts carrying mutation in NPC1 gene

(2012) Malgorzata E. Sztolsztener et al.   Molecular BioSystems

Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway

(2012) Benxu Cheng et al.   NEUROCHEMISTRY INTERNATIONAL

Cross-Talk between NFkB and the PI3-Kinase/AKT Pathway Can Be Targeted in Primary Effusion Lymphoma (PEL) Cell Lines for Efficient Apoptosis

(2012) Azhar R. Hussain et al.   PLoS One

JNK-Dependent Stat3 Phosphorylation Contributes to Akt Activation in Response to Arsenic Exposure

(2012) J. Liu et al.   TOXICOLOGICAL SCIENCES

Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis

(2011) Cameron S. McAlpine et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cholesterol trafficking is required for mTOR activation in endothelial cells

(2010) J. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol as a factor regulating intracellular localization of annexin A6 in Niemann–Pick type C human skin fibroblasts

(2009) Malgorzata E. Sztolsztener et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

TORC-Specific Phosphorylation of Mammalian Target of Rapamycin (mTOR): Phospho-Ser2481 Is a Marker for Intact mTOR Signaling Complex 2

(2009) J. Copp et al.   CANCER RESEARCH

Akt-mediated regulation of NFκB and the essentialness of NFκB for the oncogenicity of PI3K and Akt

(2009) Dong Bai et al.   INTERNATIONAL JOURNAL OF CANCER

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE