Plasma derived from human umbilical cord blood: Potential cell-additive or cell-substitute therapeutic for neurodegenerative diseases

Human Umbilical Cord Blood Serum–derived α-Secretase

(2018) Ahsan Habib et al.   CELL TRANSPLANTATION

Maternal and umbilical cord serum–derived exosomes enhance endothelial cell proliferation and migration

(2018) Linyan Jia et al.   FASEB JOURNAL

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

(2017) Joseph M. Castellano et al.   NATURE

Plasma Derived from Human Umbilical Cord Blood Modulates Mitogen-Induced Proliferation of Mononuclear Cells Isolated from the Peripheral Blood of ALS Patients

(2016) David J. Eve et al.   CELL TRANSPLANTATION

Therapeutic effects of umbilical cord blood plasma in a rat model of acute ischemic stroke

(2016) Jongman Yoo et al.   Oncotarget

Preclinical Assessment of Young Blood Plasma for Alzheimer Disease

(2016) Jinte Middeldorp et al.   JAMA Neurology

Roles of FGF signaling in stem cell self-renewal, senescence and aging

(2016) Daniel L. Coutu et al.   Aging-US

G-CSF as an Adjunctive Therapy with Umbilical Cord Blood Cell Transplantation for Traumatic Brain Injury

(2015) Ike De La Peña et al.   CELL TRANSPLANTATION

Human Umbilical Cord Blood-Derived Monocytes Improve Cognitive Deficits and Reduce Amyloid-β Pathology in PSAPP Mice

(2015) Donna Darlington et al.   CELL TRANSPLANTATION

Humoral factors in ALS patients during disease progression

(2015) Jared Ehrhart et al.   Journal of Neuroinflammation

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

Combination Therapy of Human Umbilical Cord Blood Cells and Granulocyte Colony Stimulating Factor Reduces Histopathological and Motor Impairments in an Experimental Model of Chronic Traumatic Brain Injury

(2014) Sandra A. Acosta et al.   PLoS One

MSCs Conditioned Media and Umbilical Cord Blood Plasma Metabolomics and Composition

(2014) Tiago Pereira et al.   PLoS One

Blood-CNS Barrier Impairment in ALS patients versus an animal model

(2014) Svitlana Garbuzova-Davis et al.   Frontiers in Cellular Neuroscience

Roles of Vascular Endothelial Growth Factor in Amyotrophic Lateral Sclerosis

(2014) Ana Catarina Pronto-Laborinho et al.   Biomed Research International

Experimental research Effects of intravenous human umbilical cord blood CD34+ stem cell therapy versus levodopa

(2013) Noha Abo-Grisha et al.   Archives of Medical Science

Normative levels of Interleukin 16 in umbilical cord blood

(2013) N.M. Denihan et al.   CLINICAL BIOCHEMISTRY

Human umbilical cord-derived MSC culture: the replacement of animal sera with human cord blood plasma

(2013) Yan Ding et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Gene and protein therapies utilizing VEGF for ALS

(2013) Orion P. Keifer et al.   PHARMACOLOGY & THERAPEUTICS

Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

(2012) Ethan A. Winkler et al.   ACTA NEUROPATHOLOGICA

A Meta-Analysis of Unrelated Donor Umbilical Cord Blood Transplantation versus Unrelated Donor Bone Marrow Transplantation in Acute Leukemia Patients

(2012) Haoran Zhang et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Impaired blood–brain/spinal cord barrier in ALS patients

(2012) Svitlana Garbuzova-Davis et al.   BRAIN RESEARCH

Multiple Intravenous Administrations of Human Umbilical Cord Blood Cells Benefit in a Mouse Model of ALS

(2012) Svitlana Garbuzova-Davis et al.   PLoS One

Multiple Low-Dose Infusions of Human Umbilical Cord Blood Cells Improve Cognitive Impairments and Reduce Amyloid-β-Associated Neuropathology in Alzheimer Mice

(2012) Donna Darlington et al.   STEM CELLS AND DEVELOPMENT

Determination of the Therapeutic Time Window for Human Umbilical Cord Blood Mononuclear Cell Transplantation following Experimental Stroke in Rats

(2011) Johannes Boltze et al.   CELL TRANSPLANTATION

Application of Umbilical Cord Serum Eyedrops for Recurrent Corneal Erosions

(2011) Kyung-Chul Yoon et al.   CORNEA

Human umbilical cord blood plasma can replace fetal bovine serum for in vitro expansion of functional human endothelial colony-forming cells

(2011) Lan Huang et al.   CYTOTHERAPY

Microbleeds relate to altered amyloid-beta metabolism in Alzheimer's disease

(2011) Jeroen D.C. Goos et al.   NEUROBIOLOGY OF AGING

“Humanized” Stem Cell Culture Techniques: The Animal Serum Controversy

(2011) Chandana Tekkatte et al.   Stem Cells International

The effects of platelet-rich plasma derived from human umbilical cord blood on the osteogenic differentiation of human dental stem cells

(2010) Jung-Yeon Lee et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Strategies to enhance umbilical cord blood stem cell engraftment in adult patients

(2010) Colleen Delaney et al.   Expert Review of Hematology

DECREASED mRNA EXPRESSION OF TIGHT JUNCTION PROTEINS IN LUMBAR SPINAL CORDS OF PATIENTS WITH ALS

(2009) J. S. Henkel et al.   NEUROLOGY

Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer

(2008) Min Li et al.   CANCER SCIENCE

CXCL8/IL8 Stimulates Vascular Endothelial Growth Factor (VEGF) Expression and the Autocrine Activation of VEGFR2 in Endothelial Cells by Activating NFκB through the CBM (Carma3/Bcl10/Malt1) Complex

(2008) Daniel Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Umbilical Cord Blood Treatment in a Mouse Model of ALS: Optimization of Cell Dose

(2008) Svitlana Garbuzova-Davis et al.   PLoS One

Peripherally Administered Human Umbilical Cord Blood Cells Reduce Parenchymal and Vascular β-Amyloid Deposits in Alzheimer Mice

(2008) William V. Nikolic et al.   STEM CELLS AND DEVELOPMENT

Increased activation of GATA-3, IL-2 and IL-5 of cord blood mononuclear cells in infants with IgE sensitization

(2007) Emma Marschan et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY