The AAA ATPase Afg1 preserves mitochondrial fidelity and cellular health by maintaining mitochondrial matrix proteostasis

Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins

(2017) Matthew L. Wohlever et al.   MOLECULAR CELL

The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane

(2017) Nicholas R Weir et al.   eLife

The mammalian homologue of yeast Afg1 ATPase (lactation elevated 1) mediates degradation of nuclear-encoded complex IV subunits

(2016) J. Cesnekova et al.   BIOCHEMICAL JOURNAL

Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes

(2016) Samantha Swenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Assembly Factor Pet117 Couples Heme a Synthase Activity to Cytochrome Oxidase Assembly

(2016) Nicholas G. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Quality Control Proteases in Neuronal Welfare

(2016) Roman M. Levytskyy et al.   Journal of Neuroimmune Pharmacology

Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

(2016) Jonathan A Stefely et al.   NATURE BIOTECHNOLOGY

LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis

(2016) Jana Cesnekova et al.   Oncotarget

Mitochondrial Protein Quality Control: The Mechanisms Guarding Mitochondrial Health

(2015) Iryna Bohovych et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis

(2015) Julia R. Kardon et al.   CELL

Neuronal Serotonin Release Triggers the Heat Shock Response in C. elegans in the Absence of Temperature Increase

(2015) Marcus C. Tatum et al.   CURRENT BIOLOGY

Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability

(2015) Iryna Bohovych et al.   Scientific Reports

Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins

(2014) Y.-C. Chen et al.   EMBO JOURNAL

Stress-triggered Activation of the Metalloprotease Oma1 Involves Its C-terminal Region and Is Important for Mitochondrial Stress Protection in Yeast

(2014) Iryna Bohovych et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disturbed mitochondrial dynamics and neurodegenerative disorders

(2014) Florence Burté et al.   Nature Reviews Neurology

NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import

(2014) Natalie Al-Furoukh et al.   PLoS One

The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins

(2014) V. Okreglak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans

(2014) Christopher F. Bennett et al.   Nature Communications

A mitochondrial bioenergetic etiology of disease

(2013) Douglas C. Wallace   JOURNAL OF CLINICAL INVESTIGATION

Dopamine Modulates Acetylcholine Release via Octopamine and CREB Signaling in Caenorhabditis elegans

(2013) Satoshi Suo et al.   PLoS One

Circadian clock adjustment to plant iron status depends on chloroplast and phytochrome function

(2012) Patrice A Salomé et al.   EMBO JOURNAL

Mitochondrial quality control: a matter of life and death for neurons

(2012) Elena I Rugarli et al.   EMBO JOURNAL

Selective Oma1 Protease-mediated Proteolysis of Cox1 Subunit of Cytochrome Oxidase in Assembly Mutants

(2012) Oleh Khalimonchuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria

(2012) Bernadette Schreiner et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae

(2012) Mohan Babu et al.   NATURE

Identification of the Cdc48bullet20S Proteasome as an Ancient AAA+ Proteolytic Machine

(2012) D. Barthelme et al.   SCIENCE

Neurodegeneration as a consequence of failed mitochondrial maintenance

(2011) Mariusz Karbowski et al.   ACTA NEUROPATHOLOGICA

AAA+ Proteases: ATP-Fueled Machines of Protein Destruction

(2011) Robert T. Sauer et al.   Annual Review of Biochemistry

The AAA+ ATPase Thorase Regulates AMPA Receptor-Dependent Synaptic Plasticity and Behavior

(2011) Jianmin Zhang et al.   CELL

A Pathway of Protein Translocation in Mitochondria Mediated by the AAA-ATPase Bcs1

(2011) Nikola Wagener et al.   MOLECULAR CELL

A Genome-wide Drosophila Screen for Heat Nociception Identifies α2δ3 as an Evolutionarily Conserved Pain Gene

(2010) G. Gregory Neely et al.   CELL

The role of protein quality control in mitochondrial protein homeostasis under oxidative stress

(2010) Tom Bender et al.   PROTEOMICS

Methionine sulfoxide reductase A expression is regulated by the DAF-16/FOXO pathway inCaenorhabditis elegans

(2009) Alicia N. Minniti et al.   AGING CELL

Formation of the Redox Cofactor Centers during Cox1 Maturation in Yeast Cytochrome Oxidase

(2009) O. Khalimonchuk et al.   MOLECULAR AND CELLULAR BIOLOGY