The α2δ-1–NMDA receptor coupling is essential for corticostriatal long-term potentiation and is involved in learning and memory

α2δ-1 Is Essential for Sympathetic Output and NMDA Receptor Activity Potentiated by Angiotensin II in the Hypothalamus

(2018) Huijie Ma (马会杰) et al.   JOURNAL OF NEUROSCIENCE

α2δ-1 couples to NMDA receptors in the hypothalamus to sustain sympathetic vasomotor activity in hypertension

(2018) Huijie Ma et al.   JOURNAL OF PHYSIOLOGY-LONDON

The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions

(2018) Jinjun Chen et al.   Cell Reports

BK Potassium Channels Suppress Cavα2δ Subunit Function to Reduce Inflammatory and Neuropathic Pain

(2018) Fang-Xiong Zhang et al.   Cell Reports

Focal Cerebral Ischemia and Reperfusion Induce Brain Injury Through α2δ-1–Bound NMDA Receptors

(2018) Yi Luo et al.   STROKE

CaMKII Regulates Synaptic NMDA Receptor Activity of Hypothalamic Presympathetic Neurons and Sympathetic Outflow in Hypertension

(2017) De-Pei Li et al.   JOURNAL OF NEUROSCIENCE

Alpha2delta-1 in SF1 + Neurons of the Ventromedial Hypothalamus Is an Essential Regulator of Glucose and Lipid Homeostasis

(2017) Jennifer A. Felsted et al.   Cell Reports

Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain

(2016) Lingyong Li et al.   Cell Reports

Thrombospondin-4 reduces binding affinity of [3H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed

(2016) Beatrice Lana et al.   Scientific Reports

Theta-burst LTP

(2015) John Larson et al.   BRAIN RESEARCH

Upregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker rats

(2015) Jing-Jing Zhou et al.   NEUROPHARMACOLOGY

Use of the Open Field Maze to Measure Locomotor and Anxiety-like Behavior in Mice

(2015) Michael L. Seibenhener et al.   Jove-Journal of Visualized Experiments

mGluR5 Upregulation Increases Excitability of Hypothalamic Presympathetic Neurons through NMDA Receptor Trafficking in Spontaneously Hypertensive Rats

(2014) D.-P. Li et al.   JOURNAL OF NEUROSCIENCE

Essential Role of Presynaptic NMDA Receptors in Activity-Dependent BDNF Secretion and Corticostriatal LTP

(2014) Hyungju Park et al.   NEURON

Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary  2 -1 subunits

(2014) J. S. Cassidy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An open-source toolbox for automated phenotyping of mice in behavioral tasks

(2014) Tapan P. Patel et al.   Frontiers in Behavioral Neuroscience

Sensitivity to theta-burst timing permits LTP in dorsal striatal adult brain slice

(2013) Sarah L. Hawes et al.   JOURNAL OF NEUROPHYSIOLOGY

Expression of NMDA receptor-dependent LTP in the hippocampus: bridging the divide

(2013) Tim VP Bliss et al.   Molecular Brain

α2δ expression sets presynaptic calcium channel abundance and release probability

(2012) Michael B. Hoppa et al.   NATURE

Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

(2012) Annette C. Dolphin   NATURE REVIEWS NEUROSCIENCE

Blockade of NMDA receptors 2A subunit in the dorsal striatum impairs the learning of a complex motor skill.

(2011) Julie Lemay-Clermont et al.   BEHAVIORAL NEUROSCIENCE

Contributions of dorsal striatal subregions to spatial alternation behavior

(2011) R. Moussa et al.   LEARNING & MEMORY

Presynaptic BDNF Promotes Postsynaptic Long-Term Potentiation in the Dorsal Striatum

(2010) Y. Jia et al.   JOURNAL OF NEUROSCIENCE

Opioid-Induced Long-Term Potentiation in the Spinal Cord Is a Presynaptic Event

(2010) H.-Y. Zhou et al.   JOURNAL OF NEUROSCIENCE

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain

(2010) C. S. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted disruption of the voltage-dependent calcium channel α2/δ-1-subunit

(2009) Geraldine A. Fuller-Bicer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Corticostriatal Interactions during Learning, Memory Processing, and Decision Making

(2009) C. M. A. Pennartz et al.   JOURNAL OF NEUROSCIENCE

Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill

(2009) Henry H Yin et al.   NATURE NEUROSCIENCE

Reward-guided learning beyond dopamine in the nucleus accumbens: the integrative functions of cortico-basal ganglia networks

(2008) Henry H. Yin et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Immunostaining of rat brain, spinal cord, sensory neurons and skeletal muscle for calcium channel alpha2-delta (α2-δ) type 1 protein

(2008) C.P. Taylor et al.   NEUROSCIENCE

Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task

(2008) A. B. L. Tort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia

(2008) Keizo Takao et al.   Molecular Brain