Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

Mutant PrP Suppresses Glutamatergic Neurotransmission in Cerebellar Granule Neurons by Impairing Membrane Delivery of VGCC α2δ-1 Subunit

(2012) Assunta Senatore et al.   NEURON

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy

(2011) Tara Klassen et al.   CELL

Identification of a disulfide bridge essential for structure and function of the voltage-gated Ca2+ channel α2δ-1 auxiliary subunit

(2011) Aida Calderón-Rivera et al.   CELL CALCIUM

Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)

(2011) C. Templin et al.   EUROPEAN HEART JOURNAL

The CaV1.4 Calcium Channel Is a Critical Regulator of T Cell Receptor Signaling and Naive T Cell Homeostasis

(2011) Kyla Omilusik et al.   IMMUNITY

Newer-Generation Antiepileptic Drugs and the Risk of Major Birth Defects

(2011) Ditte Mølgaard-Nielsen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Functional Coupling of Rab3-interacting Molecule 1 (RIM1) and L-type Ca2+Channels in Insulin Release

(2011) María A. Gandini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Subunits Promote the Expression of CaV2.2 Channels by Reducing Their Proteasomal Degradation

(2011) Dominic Waithe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homodimerization of the Src Homology 3 Domain of the Calcium Channel β-Subunit Drives Dynamin-dependent Endocytosis

(2011) Erick Miranda-Laferte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stargazin-related protein  7 is associated with signalling endosomes in superior cervical ganglion neurons and modulates neurite outgrowth

(2011) D. Waithe et al.   JOURNAL OF CELL SCIENCE

Lateral Mobility of Presynaptic L-Type Calcium Channels at Photoreceptor Ribbon Synapses

(2011) A. J. Mercer et al.   JOURNAL OF NEUROSCIENCE

Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors

(2011) Fujun Chen et al.   NATURE NEUROSCIENCE

Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses

(2011) Zhuo Huang et al.   NATURE NEUROSCIENCE

Rem2-Targeted shRNAs Reduce Frequency of Miniature Excitatory Postsynaptic Currents without Altering Voltage-Gated Ca2+ Currents

(2011) Hong-Gang Wang et al.   PLoS One

RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release

(2011) K. S. Y. Liu et al.   SCIENCE

Structural and functional differences between L-type calcium channels: crucial issues for future selective targeting

(2011) Annalisa Zuccotti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Voltage-Gated Calcium Channels

(2011) W. A. Catterall   Cold Spring Harbor Perspectives in Biology

A Genome-wide Drosophila Screen for Heat Nociception Identifies α2δ3 as an Evolutionarily Conserved Pain Gene

(2010) G. Gregory Neely et al.   CELL

Exploring the function and pharmacotherapeutic potential ­of voltage-gated Ca2+channels with gene-knockout models

(2010) Jörg Striessnig et al.   Channels

Multiple C-terminal tail Ca2+/CaMs regulate CaV1.2 function but do not mediate channel dimerization

(2010) Eun Young Kim et al.   EMBO JOURNAL

Oligomerization of Cavβ subunits is an essential correlate of Ca2+ channel activity

(2010) Qi Zong Lao et al.   FASEB JOURNAL

Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death

(2010) Elena Burashnikov et al.   HEART RHYTHM

The  2  Ligand Gabapentin Inhibits the Rab11-Dependent Recycling of the Calcium Channel Subunit  2 -2

(2010) A. Tran-Van-Minh et al.   JOURNAL OF NEUROSCIENCE

The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels

(2010) Christophe Altier et al.   NATURE NEUROSCIENCE

The β Subunit of Voltage-Gated Ca2+ Channels

(2010) Zafir Buraei et al.   PHYSIOLOGICAL REVIEWS

Direct inhibition of P/Q-type voltage-gated Ca2+ channels by Gem does not require a direct Gem/Cav  interaction

(2010) M. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain

(2010) C. S. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The  2  subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function

(2010) A. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted disruption of the voltage-dependent calcium channel α2/δ-1-subunit

(2009) Geraldine A. Fuller-Bicer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Calcium channel diversity: multiple roles of calcium channel subunits

(2009) Annette C Dolphin   CURRENT OPINION IN NEUROBIOLOGY

The β Subunit of Voltage-gated Ca2+Channels Interacts with and Regulates the Activity of a Novel Isoform of Pax6

(2009) Yun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N Terminus Is Key to the Dominant Negative Suppression of CaV2 Calcium Channels

(2009) Karen M. Page et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three-dimensional Structure of CaV3.1

(2009) Conor P. Walsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt regulates L-type Ca2+channel activity by modulating Cavα1 protein stability

(2009) Daniele Catalucci et al.   JOURNAL OF CELL BIOLOGY

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

Cav1.3 Channel Voltage Dependence, Not Ca2+ Selectivity, Drives Pacemaker Activity and Amplifies Bursts in Nigral Dopamine Neurons

(2009) I. Putzier et al.   JOURNAL OF NEUROSCIENCE

The Ca2+ Channel Subunit  2 Regulates Ca2+ Channel Abundance and Function in Inner Hair Cells and Is Required for Hearing

(2009) J. Neef et al.   JOURNAL OF NEUROSCIENCE

The Increased Trafficking of the Calcium Channel Subunit  2 -1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the  2  Ligand Pregabalin

(2009) C. S. Bauer et al.   JOURNAL OF NEUROSCIENCE

Defective survival of naive CD8+ T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels

(2009) Mithilesh K Jha et al.   NATURE IMMUNOLOGY

Presynaptic α2δ-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions

(2009) Peri T Kurshan et al.   NATURE NEUROSCIENCE

Presynaptic CaV2 calcium channel traffic requires CALF-1 and the α2δ subunit UNC-36

(2009) Yasunori Saheki et al.   NATURE NEUROSCIENCE

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

From Basic Science to Blockbuster Drug: The Discovery of Lyrica

(2008) Richard B. Silverman   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α2δ1 Dihydropyridine Receptor Subunit Is a Critical Element for Excitation-Coupled Calcium Entry but Not for Formation of Tetrads in Skeletal Myotubes

(2008) Marcin P. Gach et al.   BIOPHYSICAL JOURNAL

Thrombospondins: from structure to therapeutics

(2008) S. Kazerounian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

T-type Ca2+ channels as therapeutic targets in the nervous system

(2008) H SHIN et al.   CURRENT OPINION IN PHARMACOLOGY

Methylation of the Calcium Channel-Related Gene, CACNA2D3, Is Frequent and a Poor Prognostic Factor in Gastric Cancer

(2008) Aira Wanajo et al.   GASTROENTEROLOGY

Proper Restoration of Excitation-Contraction Coupling in the Dihydropyridine Receptor β1-null ZebrafishRelaxedIs an Exclusive Function of the β1aSubunit

(2008) Johann Schredelseker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ablation of Ca2+Channel β3 Subunit Leads to EnhancedN-Methyl-d-aspartate Receptor-dependent Long Term Potentiation and Improved Long Term Memory

(2008) Daejong Jeon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in a Drosophila  2  Voltage-Gated Calcium Channel Subunit Reveal a Crucial Synaptic Function

(2008) D. K. Dickman et al.   JOURNAL OF NEUROSCIENCE

Origin of the Voltage Dependence of G-Protein Regulation of P/Q-type Ca2+ Channels

(2008) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Pregabalin for Postherpetic Neuralgia: Placebo-Controlled Trial of Fixed and Flexible Dosing Regimens on Allodynia and Time to Onset of Pain Relief

(2008) Brett R. Stacey et al.   JOURNAL OF PAIN

Immunostaining of rat brain, spinal cord, sensory neurons and skeletal muscle for calcium channel alpha2-delta (α2-δ) type 1 protein

(2008) C.P. Taylor et al.   NEUROSCIENCE

Ca2+ channel-independent requirement for MAGUK family CACNB4 genes in initiation of zebrafish epiboly

(2008) A. M. Ebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological disruption of calcium channel trafficking by the  2  ligand gabapentin

(2008) J. Hendrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The calcium channel α2/δ1 subunit is involved in extracellular signalling

(2007) Kelly García et al.   JOURNAL OF PHYSIOLOGY-LONDON

A short history of voltage-gated calcium channels

(2006) Annette C Dolphin   BRITISH JOURNAL OF PHARMACOLOGY