The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA

MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria

(2016) Ilaria Dalla Rosa et al.   PLoS Genetics

The Human Mitochondrial DNA Depletion Syndrome GeneMPV17Encodes a Non-selective Channel That Modulates Membrane Potential

(2015) Vasily D. Antonenkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial DNA depletion syndrome causing liver failure

(2014) Sunita Bijarnia-Mahay et al.   INDIAN PEDIATRICS

Nuclear Enrichment of Folate Cofactors and Methylenetetrahydrofolate Dehydrogenase 1 (MTHFD1) Protectde NovoThymidylate Biosynthesis during Folate Deficiency

(2014) Martha S. Field et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HumanSLC25A33andSLC25A36Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters

(2014) Maria Antonietta Di Noia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Sensitizing Cancer Cells: Is It Really All about U?

(2012) Patrick J. Stover et al.   CANCER CELL

Serine Hydroxymethyltransferase Anchorsde NovoThymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis

(2012) Donald D. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MPV17 mutation causes neuropathy and leukoencephalopathy with multiple mtDNA deletions in muscle

(2012) Emma L. Blakely et al.   NEUROMUSCULAR DISORDERS

Hepatocerebral form of mitochondrial DNA depletion syndrome due to mutation in MPV17 gene

(2012) Abdulaziz AlSaman et al.   Saudi Journal of Gastroenterology

Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria

(2011) D. D. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Limited dCTP Availability Accounts for Mitochondrial DNA Depletion in Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)

(2011) Emiliano González-Vioque et al.   PLoS Genetics

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

Mitochondrial DNA deletions of blood lymphocytes as genetic markers of low folate-related mitochondrial genotoxicity in peripheral tissues

(2009) Yi-Fang Chou et al.   EUROPEAN JOURNAL OF NUTRITION

Depleted folate pool and dysfunctional mitochondria associated with defective mitochondrial folate proteins sensitize Chinese ovary cell mutants to tert-butylhydroperoxide-induced oxidative stress and apoptosis

(2009) Yi-Ling Ye et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cytoplasmic Serine Hydroxymethyltransferase Regulates the Metabolic Partitioning of Methylenetetrahydrofolate but Is Not Essential in Mice

(2008) Amanda J. MacFarlane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY