Alzheimer’s Disease Presenilin-1 Mutation Sensitizes Neurons to Impaired Autophagy Flux and Propofol Neurotoxicity: Role of Calcium Dysregulation
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Title
Alzheimer’s Disease Presenilin-1 Mutation Sensitizes Neurons to Impaired Autophagy Flux and Propofol Neurotoxicity: Role of Calcium Dysregulation
Authors
Keywords
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Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume 67, Issue 1, Pages 137-147
Publisher
IOS Press
Online
2019-01-09
DOI
10.3233/jad-180858
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Note: Only part of the references are listed.- Anesthetic neurotoxicity: Apoptosis and autophagic cell death mediated by calcium dysregulation
- (2017) Meirong Yang et al. NEUROTOXICOLOGY AND TERATOLOGY
- Effects of Propofol Treatment in Neural Progenitors Derived from Human-Induced Pluripotent Stem Cells
- (2017) Bo Long et al. NEURAL PLASTICITY
- General Anesthetics Regulate Autophagy via Modulating the Inositol 1,4,5-Trisphosphate Receptor: Implications for Dual Effects of Cytoprotection and Cytotoxicity
- (2017) Gongyi Ren et al. Scientific Reports
- Intracellular Ca 2+ signaling and Ca 2+ microdomains in the control of cell survival, apoptosis and autophagy
- (2016) Rita M.L. La Rovere et al. CELL CALCIUM
- Intracellular calcium signaling regulates autophagy via calcineurin-mediated TFEB dephosphorylation
- (2015) Yanju Tong et al. Autophagy
- Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion
- (2015) Caroline Mauvezin et al. Autophagy
- Membrane depolarization increases ryanodine sensitivity to Ca2+ release to the cytosol in L6 skeletal muscle cells: Implications for excitation–contraction coupling
- (2015) Saumitra Pitake et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification
- (2015) Ju-Hyun Lee et al. Cell Reports
- General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening
- (2014) J. Donald Joseph et al. ANESTHESIOLOGY
- Isoflurane induces endoplasmic reticulum stress and caspase activation through ryanodine receptors
- (2014) H. Wang et al. BRITISH JOURNAL OF ANAESTHESIA
- Suppression of InsP3 Receptor-Mediated Ca2+ Signaling Alleviates Mutant Presenilin-Linked Familial Alzheimer's Disease Pathogenesis
- (2014) D. Shilling et al. JOURNAL OF NEUROSCIENCE
- Comparison of Neurodegeneration and Cognitive Impairment in Neonatal Mice Exposed to Propofol or Isoflurane
- (2014) Bin Yang et al. PLoS One
- Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers
- (2014) Hwan-Woo Park et al. Nature Communications
- Dual Effects of Isoflurane on Proliferation, Differentiation, and Survival in Human Neuroprogenitor Cells
- (2013) Xuli Zhao et al. ANESTHESIOLOGY
- Presenilin-ryanodine receptor connection
- (2013) L. D'Adamio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dual effects of neuroprotection and neurotoxicity by general anesthetics: Role of intracellular calcium homeostasis
- (2013) Huafeng Wei et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice
- (2012) Jun Peng et al. NEUROSCIENCE LETTERS
- Isoflurane Induces Learning Impairment That Is Mediated by Interleukin 1β in Rodents
- (2012) Lin Cao et al. PLoS One
- Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease
- (2011) E. D. Roberson et al. JOURNAL OF NEUROSCIENCE
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- Inhalation anesthetic-induced neuronal damage in the developing rhesus monkey
- (2011) Xiaoju Zou et al. NEUROTOXICOLOGY AND TERATOLOGY
- Anesthetic Propofol Attenuates the Isoflurane-Induced Caspase-3 Activation and Aβ Oligomerization
- (2011) Yiying Zhang et al. PLoS One
- Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk
- (2011) E. Zampese et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exposure to general anesthesia and risk of Alzheimer's disease: a systematic review and meta-analysis
- (2011) Dallas P Seitz et al. BMC Geriatrics
- Calcium Dysregulation and Homeostasis of Neural Calcium in the Molecular Mechanisms of Neurodegenerative Diseases Provide Multiple Targets for Neuroprotection
- (2010) Gregor Zündorf et al. ANTIOXIDANTS & REDOX SIGNALING
- Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
- (2010) Dun-Sheng Yang et al. BRAIN
- Isoflurane Anesthesia Induced Persistent, Progressive Memory Impairment, Caused a Loss of Neural Stem Cells, and Reduced Neurogenesis in Young, but Not Adult, Rodents
- (2010) Changlian Zhu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Anesthetic-Induced Neurodegeneration Mediated via Inositol 1,4,5-Trisphosphate Receptors
- (2010) Y. Zhao et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Gain-of-Function Enhancement of IP3 Receptor Modal Gating by Familial Alzheimer's Disease-Linked Presenilin Mutants in Human Cells and Mouse Neurons
- (2010) K.-H. Cheung et al. Science Signaling
- The common inhaled anesthetic isoflurane increases aggregation of huntingtin and alters calcium homeostasis in a cell model of Huntington's disease
- (2010) Qiujun Wang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- A Presenilin-1 Mutation Renders Neurons Vulnerable to Isoflurane Toxicity
- (2009) Ge Liang et al. ANESTHESIA AND ANALGESIA
- The Common Inhalational Anesthetic Isoflurane Induces Apoptosis via Activation of Inositol 1,4,5-Trisphosphate Receptors
- (2009) Huafeng Wei et al. ANESTHESIOLOGY
- Mitochondria, calcium and cell death: A deadly triad in neurodegeneration
- (2009) Fulvio Celsi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
- (2008) Tadanori Hamano et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics
- (2007) Shannon L. Bianchi et al. NEUROBIOLOGY OF AGING
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