Article
Biochemistry & Molecular Biology
Qing Sun, Peiyu Zhang, Zixuan Zhao, Xuefang Sun, Xiang Liu, Hongsheng Zhang, Wen Jiang
Summary: This study investigated the transcriptomic changes in maize with low-P-sensitive and -tolerant genotypes under low-P stress and its symbiotic interaction with T. purpurogenus. The results showed that T. purpurogenus enhanced plant growth and P uptake, especially in the low-P-sensitive genotype. Transcriptome analysis revealed distinct molecular responses and functional pathways in the two genotypes after T. purpurogenus inoculation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Stephanie Faith Ravelo, Nino Posadas, Cecilia Conaco
Summary: In this study, the metatranscriptome of symbionts associated with a common scleractinian coral in the Philippines was sequenced to understand their genetic complement and stress response mechanisms. The analysis revealed conserved features of coral-algal symbiosis and provided insights into the potential genetic response to acute thermal stress.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Multidisciplinary Sciences
Christina Plattner, Giorgia Lamberti, Peter Blattmann, Alexander Kirchmair, Dietmar Rieder, Zuzana Loncova, Gregor Sturm, Stefan Scheidl, Marieke Ijsselsteijn, Georgios Fotakis, Asma Noureen, Rebecca Lisandrelli, Nina Boeck, Niloofar Nemati, Anne Krogsdam, Sophia Daum, Francesca Finotello, Antonios Somarakis, Alexander Schafer, Doris Wilflingseder, Miguel Gonzalez Acera, Dietmar Oefner, Lukas A. Huber, Hans Clevers, Christoph Becker, Henner F. Farin, Florian R. Greten, Ruedi Aebersold, Noel F. C. C. de Miranda, Zlatko Trajanoski
Summary: Precision oncology approaches for colorectal cancer patients are not as advanced as for other solid cancers. Functional precision oncology, based on perturbing primary tumor cells, could be a personalized treatment strategy. By measuring proteome activity landscapes using patient-derived organoids, we found that kinase inhibitors could have patient-specific off-target effects and pathway crosstalk. Additionally, we observed non-genetic heterogeneity of the organoids and upregulation of stemness and differentiation genes by kinase inhibitors. Imaging mass-cytometry-based profiling of primary tumors revealed information about the tumor microenvironment and tumor-immune cell interactions.
Article
Microbiology
Zheng Qu, Hongxiang Zhang, Qianqian Wang, Huizhang Zhao, Xiaofan Liu, Yanping Fu, Yang Lin, Jiatao Xie, Jiasen Cheng, Bo Li, Daohong Jiang
Summary: The study reveals that virus-mediated endophytes may utilize plant starch as a nutrient, activating the host's defense systems to control their growth, while the endophytes counteract host suppression by producing effector-like proteins. These findings provide new insights into the interaction of virus-mediated endophytes and their hosts, expanding our understanding of symbiotic mechanisms and setting a foundation for practical applications with virus-mediated hypovirulent fungi.
Article
Multidisciplinary Sciences
M. L. Richter, I. K. Deligiannis, K. Yin, A. Danese, E. Lleshi, P. Coupland, C. A. Vallejos, K. P. Matchett, N. C. Henderson, M. Colome-Tatche, C. P. Martinez-Jimenez
Summary: The study using single-cell RNA-seq revealed cellular heterogeneity in liver cells, and found a significant interplay between gene dosage and spatial distribution.
NATURE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Jinglei Wu, Kai Li, Jian Li, Henk Schat, Yanbang Li
Summary: Excess copper has significant impacts on plants, especially in flower responses. Genes related to Fe deficiency response are affected by excess copper, leading to reduced photosynthesis parameters and chlorophyll content.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Rashid Minhas, Henry Loeffler-Wirth, Yusra H. Siddiqui, Tomasz Obrebski, Shikha Vashisht, Karim Abu Nahia, Alexandra Paterek, Angelika Brzozowska, Lukasz Bugajski, Katarzyna Piwocka, Vladimir Korzh, Hans Binder, Cecilia Lanny Winata
Summary: The study characterized the molecular profile of zebrafish sinoatrial ring (SAR) and identified key genes and signaling pathways involved in pacemaker development. Overexpression of several mammalian SAN genes were found in the zebrafish SAR, along with genes related to BMP and Wnt signaling pathways. Functional analysis of SAR-overexpressed genes revealed their novel role in heart development and physiology. The transcriptome data generated in this study provides a valuable resource for understanding pacemaker function and related heart diseases.
Article
Ecology
Bryan D. Emmett, Veronique Levesque-Tremblay, Maria J. Harrison
Summary: The research found that extraradical hyphae interact with soil microbial communities in both positive and negative ways, showing similar patterns of member enrichment but differences at lower taxonomic levels among samples from different soils. Two fungal species displayed similar compositions in the extraradical hyphae-associated community, but differed in their selection and enrichment for specific taxa. A distinct community was established within 14 days of hyphal access to the soil, with varying temporal patterns of establishment and turnover among taxonomic groups.
Article
Forestry
Fabiano Sillo, Cecilia Brunetti, Fabio Marroni, Federico Vita, Luana Beatriz dos Santos Nascimento, Alfredo Vizzini, Antonietta Mello, Raffaella Balestrini
Summary: The European hazelnut forms a symbiotic relationship with ectomycorrhizal fungi, and this study suggests that this symbiosis can help plants adapt to stress and regulate defense responses. This research has important implications for understanding novel aspects of ectomycorrhizal symbiosis.
Article
Plant Sciences
Ying-Ning Zou, Qiu-Yun Qin, Wen-Ya Ma, Li-Jun Zhou, Qiang-Sheng Wu, Yong-Jie Xu, Kamil Kuca, Abeer Hashem, Al-Bandari Fahad Al-Arjani, Khalid F. Almutairi, Elsayed Fathi Abd-Allah
Summary: Metabolomic analysis revealed the metabolic mechanisms of mycorrhiza-enhanced drought tolerance in walnuts. The results showed that AMF inoculation increased biomass production and leaf water potential in walnut under drought stress, accompanied by regulation of numerous metabolic pathways. Furthermore, the regulation of walnut metabolites by AMF exhibited differences under different stress conditions.
Article
Biochemistry & Molecular Biology
Yi Ding, Zhongjie Wang, Yali Wang, Yahong Geng, Xiaobin Wen, Yeguang Li
Summary: This study characterized the molecular mechanisms of microalgal host-pathogen interactions by applying physiological and simultaneous dual transcriptomic analysis on Graesiella emersonii-Amoeboaphelidium protococcarum interaction. The results showed that the host microalga has a conserved defense system against pathogens while the endoparasite possessed robust pathogenicity. The study provides a new promising basis for understanding algal host defense strategies and parasite pathogenicity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Laurent Sauviac, Antoine Remy, Emeline Huault, Melanie Dalmasso, Theophile Kazmierczak, Marie-Francoise Jardinaud, Ludovic Legrand, Corentin Moreau, Bryan Ruiz, Anne-Claire Cazale, Sophie Valiere, Benjamin Gourion, Laurence Dupont, Veronique Gruber, Eric Boncompagni, Eliane Meilhoc, Pierre Frendo, Florian Frugier, Claude Bruand
Summary: This study identified hundreds of plant and bacterial genes associated with nodule senescence through dual plant-bacteria RNA sequencing, providing a valuable resource for exploring the mechanisms of nodule senescence. The study revealed that genes related to both plant and bacterial cell cycle and stress responses play important roles in nodule senescence, suggesting complex regulatory networks involved in this process.
PLANT CELL AND ENVIRONMENT
(2022)
Article
Plant Sciences
Chuanya Ji, Fang Song, Chuan He, Jianyong An, Shengyu Huang, Huimin Yu, Hang Lu, Shunyuan Xiao, Marcel Bucher, Zhiyong Pan
Summary: In this study, high-throughput sequencing of the citrus plant revealed differentially expressed genes and miRNAs related to arbuscular mycorrhizal (AM) fungal colonization. A miRNA-mRNA regulatory network was constructed and several candidate miRNA families targeting known symbiotic genes or key transcription factors were identified. Furthermore, a Poncirus-specific miR477a was found to regulate AM symbiosis by targeting the GRAS family gene RAD1 in citrus plants.
PLANT CELL AND ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Chai Hao Chiu, Pawel Roszak, Martina Orvosova, Uta Paszkowski
Summary: This study reveals that chitin-derived molecules, rather than symbiosis-specific signals, can trigger lateral root formation. The LysM receptors integrate MAMP perception with developmental responses, and their role in coordinating the interaction between roots and the rhizosphere biota is conserved across different plant species.
Article
Forestry
Xianrong Che, Wenzhen Lai, Sijia Wang, Xinyang Wang, Wentao Hu, Hui Chen, Xianan Xie, Ming Tang
Summary: This study reveals the key mechanism of symbiotic Pi transport between eucalypts and arbuscular mycorrhizal fungi, and identifies the essential role of the crucial protein EgPT4 in this process.
Article
Ecology
Romain Savary, Cindy Dupuis, Frederic G. Masclaux, Ivan D. Mateus, Edward C. Rojas, Ian R. Sanders
Article
Ecology
Ivan D. Mateus, Edward C. Rojas, Romain Savary, Cindy Dupuis, Frederic G. Masclaux, Consolee Aletti, Ian R. Sanders
Article
Biodiversity Conservation
Heidi K. Mod, Daniel Scherrer, Valeria Di Cola, Olivier Broennimann, Quentin Blandenier, Frank T. Breiner, Aline Buri, Jerome Goudet, Nicolas Guex, Enrique Lara, Edward A. D. Mitchell, Helene Niculita-Hirzel, Marco Pagni, Loic Pellissier, Eric Pinto-Figueroa, Ian R. Sanders, Benedikt R. Schmidt, Christophe V. W. Seppey, David Singer, Sylvain Ursenbacher, Erika Yashiro, Jan R. van der Meer, Antoine Guisan
GLOBAL CHANGE BIOLOGY
(2020)
Article
Plant Sciences
Ricardo Pena, Chanz Robbins, Joaquim Cruz Corella, Moses Thuita, Cargele Masso, Bernard Vanlauwe, Constant Signarbieux, Alia Rodriguez, Ian R. Sanders
FRONTIERS IN PLANT SCIENCE
(2020)
Article
Plant Sciences
Cristian Rincon, Germain Droh, Lucas Villard, Frederic G. Masclaux, Assanvo N'guetta, Adolphe Zeze, Ian R. Sanders
Summary: While many molecular studies have focused on arbuscular mycorrhizal fungi (AMF) communities in temperate ecosystems, very few studies have examined tropical AMF communities using molecular techniques. Understanding the composition of AMF communities in tropical areas is important for improving crop productivity in low fertility tropical soils. The study used a hierarchical sampling approach to investigate AMF community composition at different geographical scales and across environmental gradients. pH was found to influence AMF alpha diversity and the abundance of specific taxa and families of the Glomeromycotina. Local scale assemblages and diversity did not reliably predict those at regional scales, and a large portion of variance in AMF community composition remains unexplained by soil, climate, and geography variables. Further research is needed to better understand the processes shaping tropical AMF communities and establishment for the development of sustainable tropical agroecosystems.
Editorial Material
Ecology
Ivan D. Mateus, Soon-Jae Lee, Ian R. Sanders
Article
Plant Sciences
Chanz Robbins, Joaquim Cruz Corella, Consolee Aletti, Rejane Seiler, Ivan D. Mateus, Soon-Jae Lee, Frederic G. Masclaux, Ian R. Sanders
Summary: Research has shown that progeny of homokaryons and dikaryons are genetically identical to the parent, but dikaryon progeny differ quantitatively due to unequal inheritance of nuclear genotypes. The transcription levels of biallelic genes in dikaryon progeny are higher, but decrease with greater allelic divergence. These findings suggest that quantitative genetic variation should be considered when selecting AMF lines to improve plant production.
Article
Plant Sciences
Ricardo Alexander Pena Venegas, Soon-Jae Lee, Moses Thuita, Deusdedit Peter Mlay, Cargele Masso, Bernard Vanlauwe, Alia Rodriguez, Ian R. Sanders
Summary: The study found that in tropical field conditions, the colonization and inoculation responsiveness of cassava with AMF does not always decrease with an increased P supply as expected. This suggests that maximizing the inoculation responsiveness of cassava is not necessarily only in low P availability conditions, but is dependent on cassava and fungal genotypes. Therefore, caution should be exercised when modeling plant symbiosis with AMF under different P levels in natural conditions.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biology
Anurag Chaturvedi, Joaquim Cruz Corella, Chanz Robbins, Anita Loha, Laure Menin, Natalia Gasilova, Frederic G. Masclaux, Soon-Jae Lee, Ian R. Sanders
Summary: Early-diverging fungi exhibit high levels of N6-methyldeoxyadenine (6mA) content, distinct from Dikarya and other eukaryotes. Arbuscular mycorrhizal fungi have evolved a symbiotic lifestyle with 80% of plant species worldwide, showing unique 5mC and 6mA methylation characteristics. The model AMF, R. irregularis, demonstrates differential methylation profiles, particularly in genes related to phosphate regulation, highlighting their adaptation for symbiotic relationships with important plant species.
COMMUNICATIONS BIOLOGY
(2021)
Article
Ecology
Anouk van't Padje, Malin Klein, Victor Caldas, Loreto Oyarte Galvez, Cathleen Broersma, Nicky Hoebe, Ian R. Sanders, Thomas Shimizu, E. Toby Kiers
Summary: This study used arbuscular mycorrhizal symbiosis to investigate the effects of fungal relatedness on host and fungal benefits, finding that less-related fungi were associated with increased fungal growth, lower nutrient transport, and reduced plant benefits. The research demonstrates how symbiont relatedness can mediate the benefits of symbiotic relationships.
Review
Microbiology
Erica McGale, Ian R. Sanders
Summary: The study of identifying and targeting genes that contribute quantitatively to agricultural and ecological processes is crucial for food production and conservation efforts. Applying quantitative genetic approaches to link genome variants with traits of interest in individual organisms has been a common practice. Recent research has shown that genome-to-genome mapping can reveal interactions between species that have a significant impact on a multiorganism interaction. While studies on genome interactions between plants and bacterial pathogens have been conducted, there is still a lack of understanding in plant-fungal coquantitative genetics. However, the availability of genomic information of Rhizophagus irregularis mycorrhizal isolates opens up opportunities for dual-genome methods to study beneficial mutualistic interactions.
CURRENT OPINION IN MICROBIOLOGY
(2022)
Correction
Plant Sciences
Chanz Robbins, Joaquim Cruz Corella, Consolee Aletti, Rejane Seiler, Ivan D. D. Mateus, Soon-Jae Lee, Frederic G. Masclaux, Ian R. R. Sanders