From mRNA Expression of Drug Disposition Genes to In Vivo Assessment of CYP-Mediated Biotransformation during Zebrafish Embryonic and Larval Development

Applicability of the fish embryo acute toxicity (FET) test (OECD 236) in the regulatory context of Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH)

(2018) Marta Sobanska et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Gene transcription ontogeny of hypothalamic-pituitary-thyroid axis development in early-life stage fathead minnow and zebrafish

(2018) Lucia Vergauwen et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Biotransformation in the zebrafish embryo –temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding xenobiotic benz[ a ]anthracene

(2017) Agnes Kühnert et al.   ENVIRONMENTAL POLLUTION

In Vitro Biotransformation of Two Human CYP3A Probe Substrates and Their Inhibition during Early Zebrafish Development

(2017) Evy Verbueken et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vivo EROD assays with the zebrafish ( Danio rerio ) as rapid screening tools for the detection of dioxin-like activity

(2017) Britta Kais et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Intrinsic Xenobiotic Metabolizing Enzyme Activities in Early Life Stages of Zebrafish (Danio rerio)

(2017) Jens C. Otte et al.   TOXICOLOGICAL SCIENCES

Comparison of rat and rabbit embryo–fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects

(2016) Peter T. Theunissen et al.   CRITICAL REVIEWS IN TOXICOLOGY

Euthanizing zebrafish legally in Europe

(2016) Ana M Valentim et al.   EMBO REPORTS

Comparing determination methods of detection and quantification limits for aflatoxin analysis in hazelnut

(2016) Ümit Şengül   JOURNAL OF FOOD AND DRUG ANALYSIS

Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function

(2016) Anne M. Houbrechts et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

In vitro CYP1A activity in the zebrafish: temporal but low metabolite levels during organogenesis and lack of gender differences in the adult stage

(2016) Moayad Saad et al.   REPRODUCTIVE TOXICOLOGY

Time-dependent expression and activity of cytochrome P450 1s in early life-stages of the zebrafish (Danio rerio)

(2015) Jennifer Bräunig et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

From cutting edge to guideline: A first step in harmonization of the zebrafish embryotoxicity test (ZET) by describing the most optimal test conditions and morphology scoring system

(2015) Manon Beekhuijzen et al.   REPRODUCTIVE TOXICOLOGY

Tissue-, sex- and development-specific transcription profiles of eight UDP-glucuronosyltransferase genes in zebrafish (Danio rerio) and their regulation by activator of aryl hydrocarbon receptor

(2014) Verena Christen et al.   AQUATIC TOXICOLOGY

Expression patterns of cytochrome P450 3B and 3C genes in model fish species

(2014) Lana Shaya et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Current advances on ABC drug transporters in fish

(2014) Till Luckenbach et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations

(2014) Pål A. Olsvik et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors

(2014) N. Creusot et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

A novel contact assay for testing aryl hydrocarbon receptor (AhR)-mediated toxicity of chemicals and whole sediments in zebrafish (Danio rerio) embryos

(2014) Sabrina Schiwy et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Developmental toxicity, EROD, andCYP1AmRNA expression in zebrafish embryos exposed to dioxin-like PCB126

(2014) Han Liu et al.   ENVIRONMENTAL TOXICOLOGY

Transcriptional profiles of glutathione-S-Transferase isoforms, Cyp, and AOE genes in atrazine-exposed zebrafish embryos

(2014) Branka Glisic et al.   ENVIRONMENTAL TOXICOLOGY

Role of Pregnane X Receptor and Aryl Hydrocarbon Receptor in Transcriptional Regulation of pxr, CYP2, and CYP3 Genes in Developing Zebrafish

(2014) Akira Kubota et al.   TOXICOLOGICAL SCIENCES

Fishing for Teratogens: A Consortium Effort for a Harmonized Zebrafish Developmental Toxicology Assay

(2014) Jonathan S. Ball et al.   TOXICOLOGICAL SCIENCES

DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-Implications for the fish embryo test (FET)

(2013) B. Kais et al.   AQUATIC TOXICOLOGY

Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

(2013) Stephan Fischer et al.   BMC BIOLOGY

Aspects of Larval Rearing

(2013) C. Wilson   ILAR JOURNAL

Regulation of zebrafish CYP3A65 transcription by AHR2

(2013) Chin-Teng Chang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Transcription alterations of microRNAs, cytochrome P4501A1 and 3A65, and AhR and PXR in the liver of zebrafish exposed to crude microcystins

(2013) Xiaoyu Li et al.   TOXICON

Changes in Thyroid Hormone Levels during Zebrafish Development

(2012) Juhua Chang et al.   ZOOLOGICAL SCIENCE

Toxicity induced by emodin on zebrafish embryos

(2011) Qiuxia He et al.   DRUG AND CHEMICAL TOXICOLOGY

Inter-laboratory assessment of a harmonized zebrafish developmental toxicology assay – Progress report on phase I

(2011) A.-L. Gustafson et al.   REPRODUCTIVE TOXICOLOGY

Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations

(2011) Uwe Strähle et al.   REPRODUCTIVE TOXICOLOGY

Zebrafish (Danio rerio) embryos as a model for testing proteratogens

(2011) Stefan Weigt et al.   TOXICOLOGY

Spatio-temporal development of CYP1 activity in early life-stages of zebrafish (Danio rerio)

(2010) Jens C. Otte et al.   AQUATIC TOXICOLOGY

Development of a zebrafish embryo teratogenicity assay and quantitative prediction model

(2010) Kimberly C. Brannen et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

(2010) Jared V Goldstone et al.   BMC GENOMICS

Dechorionation as a tool to improve the fish embryo toxicity test (FET) with the zebrafish (Danio rerio)

(2010) Kirsten Henn et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Zebrafish as a Model for the Study of the Phase II Cytosolic Sulfotransferases

(2010) Tzu-An Liu et al.   CURRENT DRUG METABOLISM

The thyroid-disrupting effects of long-term perfluorononanoate exposure on zebrafish (Danio rerio)

(2010) Yang Liu et al.   ECOTOXICOLOGY

A reference growth curve for nutritional experiments in zebrafish (Danio rerio) and changes in whole body proteome during development

(2010) P. Gómez-Requeni et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Cloning and Comparative Analyses of the Zebrafish Ugt Repertoire Reveal Its Evolutionary Diversity

(2010) Haiyan Huang et al.   PLoS One

Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae

(2010) W. Alderton et al.   XENOBIOTICA

Oxidative and Conjugative Xenobiotic Metabolism in Zebrafish Larvae In Vivo

(2010) Huw S. Jones et al.   Zebrafish

Normal table of postembryonic zebrafish development: Staging by externally visible anatomy of the living fish

(2009) David M. Parichy et al.   DEVELOPMENTAL DYNAMICS

The role of CYP26 enzymes in retinoic acid clearance

(2009) Jayne E Thatcher et al.   Expert Opinion on Drug Metabolism & Toxicology

Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB

(2009) Thomas B. Knudsen et al.   REPRODUCTIVE TOXICOLOGY

Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches

(2008) Marijke De Wit et al.   CHEMOSPHERE

Influence of TCDD on Zebrafish CYP1B1 Transcription during Development

(2008) Hou-Chu Yin et al.   TOXICOLOGICAL SCIENCES