Next-generation sequencing-based clinical sequencing: toward precision medicine in solid tumors

Contribution of human liver and intestinal carboxylesterases to the hydrolysis of selexipag in vitro

(2018) Shunji Imai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

HER kinase inhibition in patients with HER2- and HER3-mutant cancers

(2018) David M. Hyman et al.   NATURE

Next generation sequencing-based gene panel tests for the management of solid tumors

(2018) Masayuki Nagahashi et al.   CANCER SCIENCE

FDA Approval of PARP Inhibitors and the Impact on Genetic Counseling and Genetic Testing Practices

(2017) Kathryn M. Buchtel et al.   Journal of Genetic Counseling

Formalin-fixed paraffin-embedded sample conditions for deep next generation sequencing

(2017) Masayuki Nagahashi et al.   JOURNAL OF SURGICAL RESEARCH

Hypermutation and microsatellite instability in gastrointestinal cancers

(2017) Kizuki Yuza et al.   Oncotarget

Actionable gene-based classification toward precision medicine in gastric cancer

(2017) Hiroshi Ichikawa et al.   Genome Medicine

Novel combination of serum microRNA for detecting breast cancer in the early stage

(2016) Akihiko Shimomura et al.   CANCER SCIENCE

Classification and characterization of microsatellite instability across 18 cancer types

(2016) Ronald J Hause et al.   NATURE MEDICINE

Performance evaluation for rapid detection of pan-cancer microsatellite instability with MANTIS

(2016) Esko A. Kautto et al.   Oncotarget

Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine

(2016) Masayuki Nagahashi et al.   Genome Medicine

Genetic evaluation and testing for hereditary forms of cancer in the era of next-generation sequencing

(2016) Christine Stanislaw et al.   Cancer Biology & Medicine

Genetic risk assessment and prevention: the role of genetic testing panels in breast cancer

(2015) Jordan Lerner-Ellis et al.   Expert Review of Anticancer Therapy

Next-generation sequencing (NGS) in metastatic gastrointestinal cancer (mGIC) patients: Translation from sequence data into clinical practice.

(2015) Raphael Brandao Moreira et al.   JOURNAL OF CLINICAL ONCOLOGY

American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility

(2015) Mark E. Robson et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

(2015) Christophe Le Tourneau et al.   LANCET ONCOLOGY

High-Throughput Sequencing Technologies

(2015) Jason A. Reuter et al.   MOLECULAR CELL

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

(2015) Julie Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

From standard to new genome-based therapy of gastric cancer

(2015) Georgios D Lianos et al.   Expert Review of Gastroenterology & Hepatology

Next-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us?

(2015) Veronique G. LeBlanc et al.   Cancers

Solving the molecular diagnostic testing conundrum for Mendelian disorders in the era of next-generation sequencing: single-gene, gene panel, or exome/genome sequencing

(2014) Yuan Xue et al.   GENETICS IN MEDICINE

A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment

(2014) Heather Hampel et al.   GENETICS IN MEDICINE

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

A pan-cancer proteomic perspective on The Cancer Genome Atlas

(2014) Rehan Akbani et al.   Nature Communications

Next generation sequencing in cancer research and clinical application

(2013) Derek Shyr et al.   BIOLOGICAL PROCEDURES ONLINE

Punctuated Evolution of Prostate Cancer Genomes

(2013) Sylvan C. Baca et al.   CELL

Lessons from the Cancer Genome

(2013) Levi A. Garraway et al.   CELL

Next-generation sequencing for lung cancer

(2013) Kehua Wu et al.   Future Oncology

Somatic Mutations in MLH1 and MSH2 Are a Frequent Cause of Mismatch-Repair Deficiency in Lynch Syndrome-Like Tumors

(2013) Arjen R. Mensenkamp et al.   GASTROENTEROLOGY

From human genome to cancer genome: The first decade

(2013) D. A. Wheeler et al.   GENOME RESEARCH

Clinical Analysis and Interpretation of Cancer Genome Data

(2013) Eliezer M. Van Allen et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

A Genomics-Based Classification of Human Lung Tumors

(2013)   Science Translational Medicine

The Genomic Landscape of Breast Cancer as a Therapeutic Roadmap

(2013) Matthew J. Ellis et al.   Cancer Discovery

Clinical application of amplicon-based next-generation sequencing in cancer

(2013) Fengqi Chang et al.   Cancer Genetics

Next-generation sequencing in breast cancer

(2012) Christine Desmedt et al.   CURRENT OPINION IN ONCOLOGY

Discovery of small molecule cancer drugs: Successes, challenges and opportunities

(2012) Swen Hoelder et al.   Molecular Oncology

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Big science: The cancer genome challenge

(2010) Heidi Ledford   NATURE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE