Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study

Multicentric Standardized Flow Cytometry Routine Assessment of Patients With Sepsis to Predict Clinical Worsening

(2018) Thomas Daix et al.   CHEST

Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study

(2018) Andrew Conway Morris et al.   INTENSIVE CARE MEDICINE

The intensive care medicine research agenda on septic shock

(2017) Anders Perner et al.   INTENSIVE CARE MEDICINE

Sepsis: frontiers in supportive care, organisation and research

(2017) Anders Perner et al.   INTENSIVE CARE MEDICINE

Advances in the understanding and treatment of sepsis-induced immunosuppression

(2017) Fabienne Venet et al.   Nature Reviews Nephrology

Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study

(2017) Brendon P Scicluna et al.   Lancet Respiratory Medicine

Toward Smarter Lumping and Smarter Splitting: Rethinking Strategies for Sepsis and Acute Respiratory Distress Syndrome Clinical Trial Design

(2016) Hallie C. Prescott et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria

(2016) Derek C. Angus et al.   CRITICAL CARE MEDICINE

Differences in Impact of Definitional Elements on Mortality Precludes International Comparisons of Sepsis Epidemiology—A Cohort Study Illustrating the Need for Standardized Reporting*

(2016) Manu Shankar-Hari et al.   CRITICAL CARE MEDICINE

Developing a New Definition and Assessing New Clinical Criteria for Septic Shock

(2016) Manu Shankar-Hari et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Frontline Science: Defects in immune function in patients with sepsis are associated with PD-1 or PD-L1 expression and can be restored by antibodies targeting PD-1 or PD-L1

(2016) Andriani C. Patera et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Early PREdiction of Severe Sepsis (ExPRES-Sepsis) study: protocol for an observational derivation study to discover potential leucocyte cell surface biomarkers

(2016) Deepankar Datta et al.   BMJ Open

Kinetics of leukocyte CD11b and CD64 expression in severe sepsis and non-infectious critical care patients

(2015) J. Jämsä et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Up-regulation of Programmed Cell Death 1 Ligand 1 on Neutrophils May Be Involved in Sepsis-induced Immunosuppression

(2015) Jia-Feng Wang et al.   ANESTHESIOLOGY

Expression of CD11c and EMR2 on neutrophils: potential diagnostic biomarkers for sepsis and systemic inflammation

(2015) S. M. Lewis et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Marked alterations of neutrophil functions during sepsis-induced immunosuppression

(2015) Julie Demaret et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Getting sepsis therapy right

(2015) R. S. Hotchkiss et al.   SCIENCE

Modern modelling techniques are data hungry: a simulation study for predicting dichotomous endpoints

(2015) Tjeerd van der Ploeg et al.   BMC Medical Research Methodology

Circulating Immature Granulocytes With T-Cell Killing Functions Predict Sepsis Deterioration*

(2014) Estelle Guérin et al.   CRITICAL CARE MEDICINE

CD24-Triggered Caspase-Dependent Apoptosis via Mitochondrial Membrane Depolarization and Reactive Oxygen Species Production of Human Neutrophils Is Impaired in Sepsis

(2014) M. Parlato et al.   JOURNAL OF IMMUNOLOGY

Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences

(2013) Janesh Pillay et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The epidemiology of adults with severe sepsis and septic shock in Scottish emergency departments

(2012) Alasdair Gray et al.   EMERGENCY MEDICINE JOURNAL

The sensitivity of neutrophil CD64 expression as a biomarker of bacterial infection is low in critically ill patients

(2012) Antoine Gros et al.   INTENSIVE CARE MEDICINE

Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure

(2011) Jonathan S. Boomer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

Disease Progression in Hemodynamically Stable Patients Presenting to the Emergency Department With Sepsis

(2010) Seth W. Glickman et al.   ACADEMIC EMERGENCY MEDICINE

Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression

(2009) Christian Meisel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Simultaneous quantitative analysis of FcγRI (CD64) and CR1 (CD35) on neutrophils in distinguishing between bacterial infections, viral infections, and inflammatory diseases

(2009) Päivi Jalava-Karvinen et al.   CLINICAL IMMUNOLOGY

Basics of standardization and calibration in cytometry - a review

(2009) Anja Mittag et al.   Journal of Biophotonics

Toward theragnostics

(2008) Frédéric Pene et al.   CRITICAL CARE MEDICINE

T lymphocytes in acute bacterial infection: increased prevalence of CD11b+cells in the peripheral blood and recruitment to the infected site

(2008) Christof Wagner et al.   IMMUNOLOGY