New insights into the function, development, and plasticity of type 2 innate lymphoid cells

The role of innate lymphoid cells in airway inflammation

(2018) Inge Kortekaas Krohn et al.   CURRENT OPINION IN PULMONARY MEDICINE

ILC2 memory: Recollection of previous activation

(2018) Itziar Martinez-Gonzalez et al.   IMMUNOLOGICAL REVIEWS

Chronic obstructive pulmonary disease subpopulations and phenotyping

(2018) Leopoldo N. Segal et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prostaglandin E 2 suppresses human group 2 innate lymphoid cell function

(2018) Jovana Maric et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epigenome analysis links gene regulatory elements in group 2 innate lymphocytes to asthma susceptibility

(2018) Ralph Stadhouders et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: The role of thymic stromal lymphopoietin

(2018) Sucai Liu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Type 2 innate lymphoid cells disrupt bronchial epithelial barrier integrity by targeting tight junctions through IL-13 in asthmatic patients

(2018) Kazunari Sugita et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Peripheral PDGFRα+gp38+mesenchymal cells support the differentiation of fetal liver–derived ILC2

(2018) Satoshi Koga et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

Allergic airway inflammation: key players beyond the Th2 cell pathway

(2017) Koichi Hirose et al.   IMMUNOLOGICAL REVIEWS

Functional and phenotypic heterogeneity of group 3 innate lymphoid cells

(2017) Felipe Melo-Gonzalez et al.   IMMUNOLOGY

Immunological Memory of Group 2 Innate Lymphoid Cells

(2017) Itziar Martinez-Gonzalez et al.   TRENDS IN IMMUNOLOGY

Alternative activation generates IL-10 producing type 2 innate lymphoid cells

(2017) Corey R. Seehus et al.   Nature Communications

Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

(2017) Medya Mara Shikhagaie et al.   Cell Reports

Cystic fibrosis and vitamin D: the quest for more pieces of the puzzle

(2016) Konstantinos Douros   ACTA PAEDIATRICA

A novel IL-10-producing innate lymphoid cells (ILC10) in a contact hypersensitivity mouse model

(2016) Hyuk Soon Kim et al.   BMB Reports

Group 2 innate lymphoid cells are increased in nasal polyps in patients with eosinophilic chronic rhinosinusitis

(2016) Ichiro Tojima et al.   CLINICAL IMMUNOLOGY

The development of adult innate lymphoid cells

(2016) Qi Yang et al.   CURRENT OPINION IN IMMUNOLOGY

A Progenitor Cell Expressing Transcription Factor RORγt Generates All Human Innate Lymphoid Cell Subsets

(2016) Steven D. Scoville et al.   IMMUNITY

Allergen-Experienced Group 2 Innate Lymphoid Cells Acquire Memory-like Properties and Enhance Allergic Lung Inflammation

(2016) Itziar Martinez-Gonzalez et al.   IMMUNITY

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia

(2016) Steven G. Smith et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Type 2 innate lymphoid cells in induced sputum from children with severe asthma

(2016) Prasad Nagakumar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2

(2016) Erin C. Zook et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD4+Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis

(2016) Florence Roan et al.   JOURNAL OF IMMUNOLOGY

NK cells and type 1 innate lymphoid cells: partners in host defense

(2016) Hergen Spits et al.   NATURE IMMUNOLOGY

Development of innate lymphoid cells

(2016) Erin C Zook et al.   NATURE IMMUNOLOGY

IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

(2016) Yoichiro Ohne et al.   NATURE IMMUNOLOGY

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

(2016) Suzanne M Bal et al.   NATURE IMMUNOLOGY

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

(2016) Jonathan S Silver et al.   NATURE IMMUNOLOGY

Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair

(2016) Zhi Li et al.   Nature Communications

Common-Lymphoid-Progenitor-Independent Pathways of Innate and T Lymphocyte Development

(2016) Maryam Ghaedi et al.   Cell Reports

Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung

(2016) Katrien C. De Grove et al.   PLoS One

Specific Induction of TSLP by the Viral RNA Analogue Poly(I:C) in Primary Epithelial Cells Derived from Nasal Polyps

(2016) Korneliusz Golebski et al.   PLoS One

Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia

(2015) J. Ho et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Novel molecular mechanism for generating NK-cell fitness and memory

(2015) Jenny M. Karo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells

(2015) Danielle Califano et al.   IMMUNITY

Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria

(2015) Jochem H. Bernink et al.   IMMUNITY

Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33

(2015) Christina A. Christianson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Bcl11b is essential for group 2 innate lymphoid cell development

(2015) Jennifer A. Walker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow

(2015) Qi Yang et al.   NATURE IMMUNOLOGY

Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets

(2015) Michelle L Robinette et al.   NATURE IMMUNOLOGY

Association between Group 2 Innate Lymphoid Cells enrichment, nasal polyps and allergy in Chronic Rhinosinusitis

(2014) D. Miljkovic et al.   ALLERGY

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin

(2014) J. Mjösberg et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The role of ILC2 in pathology of type 2 inflammatory diseases

(2014) Jochem H Bernink et al.   CURRENT OPINION IN IMMUNOLOGY

Human RORγt+CD34+ Cells Are Lineage-Specified Progenitors of Group 3 RORγt+ Innate Lymphoid Cells

(2014) Elisa Montaldo et al.   IMMUNITY

Seasonal increases in peripheral innate lymphoid type 2 cells are inhibited by subcutaneous grass pollen immunotherapy

(2014) Mongkol Lao-Araya et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Enhanced innate type 2 immune response in peripheral blood from patients with asthma

(2014) Kathleen R. Bartemes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergen challenge in allergic rhinitis rapidly induces increased peripheral blood type 2 innate lymphoid cells that express CD84

(2014) Taylor A. Doherty et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin

(2014) Brian S. Kim et al.   JOURNAL OF IMMUNOLOGY

Composition of Innate Lymphoid Cell Subsets in the Human Skin: Enrichment of NCR + ILC3 in Lesional Skin and Blood of Psoriasis Patients

(2014) Marcel B.M. Teunissen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A committed precursor to innate lymphoid cells

(2014) Michael G. Constantinides et al.   NATURE

IL-25-responsive, lineage-negative KLRG1hi cells are multipotential ‘inflammatory’ type 2 innate lymphoid cells

(2014) Yuefeng Huang et al.   NATURE IMMUNOLOGY

High Degree of Overlap between Responses to a Virus and to the House Dust Mite Allergen in Airway Epithelial Cells

(2014) Korneliusz Golebski et al.   PLoS One

Vitamin D3 metabolite calcidiol primes human dendritic cells to promote the development of immunomodulatory IL-10-producing T cells

(2014) Ghaith Bakdash et al.   VACCINE

The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor

(2014) Xiaofei Yu et al.   eLife

Interleukin-9 Is Required for Allergic Airway Inflammation Mediated by the Cytokine TSLP

(2013) Weiguo Yao et al.   IMMUNITY

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

IL-9–mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation

(2013) Jan-Eric Turner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

(2013) Maryam Salimi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type 2 innate lymphoid cells constitutively express arginase-I in the naïve and inflamed lung

(2013) Jennifer K. Bando et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

(2013) Jochem H Bernink et al.   NATURE IMMUNOLOGY

TSLP Elicits IL-33-Independent Innate Lymphoid Cell Responses to Promote Skin Inflammation

(2013) B. S. Kim et al.   Science Translational Medicine

Modulation of Signal Strength Switches Notch from an Inducer of T Cells to an Inducer of ILC2

(2013) Rebecca Gentek et al.   Frontiers in Immunology

A Deficiência de vitamina d está associada com níveis aumentados de il-17 e tnfα em pacientes com insuficiência cardíaca crônica

(2012) Milena Milovanovic et al.   Arquivos Brasileiros de Cardiologia

The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells

(2012) Jenny Mjösberg et al.   IMMUNITY

The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid Cells

(2012) Thomas Hoyler et al.   IMMUNITY

Cutting Edge: IL-17-Secreting Innate Lymphoid Cells Are Essential for Host Defense against Fungal Infection

(2012) A. Gladiator et al.   JOURNAL OF IMMUNOLOGY

The many lives of IL-9: a question of survival?

(2012) Christoph Wilhelm et al.   NATURE IMMUNOLOGY

Transcription factor RORα is critical for nuocyte development

(2012) See Heng Wong et al.   NATURE IMMUNOLOGY

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

(2011) Jenny M Mjösberg et al.   NATURE IMMUNOLOGY

Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate Lymphocytes

(2010) Cedric Vonarbourg et al.   IMMUNITY

Human NKp44+IL-22+cells and LTi-like cells constitute a stable RORC+lineage distinct from conventional natural killer cells

(2010) Natasha K. Crellin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1  reveals intrinsic functional plasticity

(2010) M. Cella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Expression of naive/memory (CD45RA/CD45RO) markers by peripheral blood CD4+ and CD8+ T cells in children with asthma

(2008) Edyta Machura et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells

(2008) Tom Cupedo et al.   NATURE IMMUNOLOGY