Mitochondrial membrane transporters and metabolic switch in heart failure

Tissue specific differences in mitochondrial DNA maintenance and expression

(2018) Elena Herbers et al.   MITOCHONDRION

Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis

(2017) Abitha Sukumaran et al.   Scientific Reports

Amalaki rasayana, a traditional Indian drug enhances cardiac mitochondrial and contractile functions and improves cardiac function in rats with hypertrophy

(2017) Vikas Kumar et al.   Scientific Reports

Unravelling the molecular basis for cardiac iron metabolism and deficiency in heart failure

(2016) Pavel Zhabyeyev et al.   EUROPEAN HEART JOURNAL

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure

(2016) Saba Haddad et al.   EUROPEAN HEART JOURNAL

Beyond the power of mitochondria

(2016) Brian O'Rourke   Nature Reviews Cardiology

Mitochondrial function as a therapeutic target in heart failure

(2016) David A. Brown et al.   Nature Reviews Cardiology

The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6

(2016) Yu Fukuda et al.   Nature Communications

Iron-induced reactive oxygen species mediate transporter DMT1 endocytosis and iron uptake in intestinal epithelial cells

(2015) Andrés Esparza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Role of Frataxin in Doxorubicin Mediated Cardiac Hypertrophy

(2015) Shravanthi Mouli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein

(2015) Katalin Kiss et al.   BIOCHEMICAL JOURNAL

Structures and functions of mitochondrial ABC transporters

(2015) T. A. Schaedler et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Biogenesis of cytosolic and nuclear iron–sulfur proteins and their role in genome stability

(2015) Viktoria Désirée Paul et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Glutathione-coordinated [2Fe–2S] cluster: a viable physiological substrate for mitochondrial ABCB7 transport

(2015) Jingwei Li et al.   CHEMICAL COMMUNICATIONS

Cardiac LXR  protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization

(2015) M. V. Cannon et al.   EMBO Molecular Medicine

Effects of plasma membrane ABCB6 on 5-aminolevulinic acid (ALA)-induced porphyrin accumulation in vitro: Tumor cell response to hypoxia

(2015) Kentaro Matsumoto et al.   Photodiagnosis and Photodynamic Therapy

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function

(2015) Samira Lakhal-Littleton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy

(2015) Subhash K. Das et al.   Scientific Reports

The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

(2014) Bao N. Puente et al.   CELL

A Conserved Mitochondrial ATP-binding Cassette Transporter Exports Glutathione Polysulfide for Cytosolic Metal Cofactor Assembly

(2014) Theresia A. Schaedler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac Metabolism in Heart Failure

(2013) Torsten Doenst et al.   CIRCULATION RESEARCH

Cardiac Metabolism and its Interactions With Contraction, Growth, and Survival of Cardiomyocytes

(2013) Stephen C. Kolwicz et al.   CIRCULATION RESEARCH

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs

(2013) Sandra R Bacman et al.   NATURE MEDICINE

Mitochondrial ABC transporters function: The role of ABCB10 (ABC-me) as a novel player in cellular handling of reactive oxygen species

(2012) Marc Liesa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Perturbations in the gene regulatory pathways controlling mitochondrial energy production in the failing heart

(2012) Gregory Aubert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo

(2012) B B Hyde et al.   CELL DEATH AND DIFFERENTIATION

Iron status in patients with chronic heart failure

(2012) E. A. Jankowska et al.   EUROPEAN HEART JOURNAL

Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives

(2012) E. A. Jankowska et al.   EUROPEAN HEART JOURNAL

Transition metals and mitochondrial metabolism in the heart

(2012) Amy K. Rines et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ABCB6 is dispensable for erythropoiesis and specifies the new blood group system Langereis

(2012) Virginie Helias et al.   NATURE GENETICS

Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export

(2012) Y. Ichikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting fatty acid and carbohydrate oxidation — A novel therapeutic intervention in the ischemic and failing heart

(2011) Jagdip S. Jaswal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial Transporter ATP Binding Cassette Mitochondrial Erythroid Is a Novel Gene Required for Cardiac Recovery After Ischemia/Reperfusion

(2011) Marc Liesa et al.   CIRCULATION

Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis

(2010) W. Chen et al.   BLOOD

Hypoxia and Fetal Heart Development

(2010) A. J. Patterson et al.   CURRENT MOLECULAR MEDICINE

Enhancing the metabolic substrate: PPAR-alpha agonists in heart failure

(2010) Satyam Sarma et al.   HEART FAILURE REVIEWS

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays

(2010) Thomas E. Gunter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondrial ABC proteins in health and disease

(2009) Ariane Zutz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Angiotensin II downregulates the fatty acid oxidation pathway in adult rat cardiomyocytes via release of tumour necrosis factor-α

(2009) Corinne Pellieux et al.   CARDIOVASCULAR RESEARCH

Modulation of Mitochondrial Proteome and Improved Mitochondrial Function by Biventricular Pacing of Dyssynchronous Failing Hearts

(2009) Giulio Agnetti et al.   Circulation-Cardiovascular Genetics

Mitochondria in cardiomyocyte Ca2+ signaling

(2009) Valeriy Lukyanenko et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The mitochondrial citrate carrier: Metabolic role and regulation of its activity and expression

(2009) Gabriele V. Gnoni et al.   IUBMB LIFE

Stimulus specific changes of energy metabolism in hypertrophied heart

(2009) S. Rimbaud et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism

(2009) F. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria

(2009) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional control of mitochondrial biogenesis: the central role of PGC-1 

(2008) R. Ventura-Clapier et al.   CARDIOVASCULAR RESEARCH

Copper deficiency inhibits Ca2+-induced swelling in rat cardiac mitochondria

(2008) W. Thomas Johnson et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mitochondrial and sarcoplasmic protein changes in hearts from copper-deficient rats: up-regulation of PGC-1α transcript and protein as a cause for mitochondrial biogenesis in copper deficiency

(2008) Denis M. Medeiros et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Manganese transport in eukaryotes: The role of DMT1

(2008) Catherine Au et al.   NEUROTOXICOLOGY