SNARE-mediated membrane fusion is a two-stage process driven by entropic forces

Ca 2+ -Triggered Synaptic Vesicle Fusion Initiated by Release of Inhibition

(2018) Axel T. Brunger et al.   TRENDS IN CELL BIOLOGY

Low energy cost for optimal speed and control of membrane fusion

(2017) Claire François-Martin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Entropic forces drive self-organization and membrane fusion by SNARE proteins

(2017) Hakhamanesh Mostafavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dilation of fusion pores by crowding of SNARE proteins

(2017) Zhenyong Wu et al.   eLife

Regulation of Exocytotic Fusion Pores by SNARE Protein Transmembrane Domains

(2017) Zhenyong Wu et al.   Frontiers in Molecular Neuroscience

Cholesterol Increases the Openness of SNARE-Mediated Flickering Fusion Pores

(2016) Benjamin S. Stratton et al.   BIOPHYSICAL JOURNAL

The mystery of the fusion pore

(2016) Satyan Sharma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mystery of the fusion pore

(2016) Satyan Sharma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Coarse-Grained Model of SNARE-Mediated Docking

(2015) Nicole Fortoul et al.   BIOPHYSICAL JOURNAL

Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis

(2015) Qiangjun Zhou et al.   NATURE

A Half-Zippered SNARE Complex Represents a Functional Intermediate in Membrane Fusion

(2014) Feng Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Microsecond Dissection of Neurotransmitter Release: SNARE-Complex Assembly Dictates Speed and Ca2+ Sensitivity

(2014) Claudio Acuna et al.   NEURON

Variable cooperativity in SNARE-mediated membrane fusion

(2014) J. M. Hernandez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium sensitive ring-like oligomers formed by synaptotagmin

(2014) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release

(2013) Peng Zhou et al.   NEURON

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

Evolution of the Hemifused Intermediate on the Pathway to Membrane Fusion

(2012) Jason M. Warner et al.   BIOPHYSICAL JOURNAL

The Hemifused State on the Pathway to Membrane Fusion

(2012) Jason M. Warner et al.   PHYSICAL REVIEW LETTERS

Single-molecule observation of helix staggering, sliding, and coiled coil misfolding

(2012) Z. Xi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Fusion Intermediates via Directional and Full Assembly of the SNARE Complex

(2012) J. M. Hernandez et al.   SCIENCE

SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open

(2012) L. Shi et al.   SCIENCE

Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages

(2012) Y. Gao et al.   SCIENCE

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

(2012) Jiajie Diao et al.   eLife

Caught in the Act: Visualization of SNARE-Mediated Fusion Events in Molecular Detail

(2011) Herre Jelger Risselada et al.   CHEMBIOCHEM

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state

(2011) Feng Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses

(2011) R. Sinha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Visualization of Large and Protein-Free Hemifusion Diaphragms

(2010) Jörg Nikolaus et al.   BIOPHYSICAL JOURNAL

One SNARE complex is sufficient for membrane fusion

(2010) Geert van den Bogaart et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A fast, single-vesicle fusion assay mimics physiological SNARE requirements

(2010) Erdem Karatekin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast Vesicle Fusion in Living Cells Requires at Least Three SNARE Complexes

(2010) R. Mohrmann et al.   SCIENCE

Single Vesicle Millisecond Fusion Kinetics Reveals Number of SNARE Complexes Optimal for Fast SNARE-mediated Membrane Fusion

(2009) Marta K. Domanska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Helical extension of the neuronal SNARE complex into the membrane

(2009) Alexander Stein et al.   NATURE

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

Synaptic vesicle fusion

(2008) Josep Rizo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY