Mast cells at the crossroads of microbiota and IBD

Mast cell chymase decreases the severity of group B Streptococcus infections

(2018) Claire Gendrin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human mast cells present antigen to autologous CD4 + T cells

(2018) Sahar Lotfi-Emran et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Vedolizumab for inflammatory bowel disease: From randomized controlled trials to real-life evidence

(2018) Maria Lia Scribano   WORLD JOURNAL OF GASTROENTEROLOGY

IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut

(2018) Giorgia Renga et al.   Cell Reports

Mast Cells Are Activated by Streptococcus pneumoniae In Vitro but Dispensable for the Host Defense Against Pneumococcal Central Nervous System Infection In Vivo

(2018) Johanna Fritscher et al.   Frontiers in Immunology

Listeria monocytogenes induces mast cell extracellular traps

(2017) Marcia Campillo-Navarro et al.   IMMUNOBIOLOGY

A β-Glucan-Based Dietary Fiber Reduces Mast Cell-Induced Hyperpermeability in Ileum From Patients With Crohn’s Disease and Control Subjects

(2017) John-Peter Ganda Mall et al.   INFLAMMATORY BOWEL DISEASES

Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes

(2017) Zhenping Wang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice

(2017) Quentin Bernard et al.   Parasites & Vectors

Rheostatic Functions of Mast Cells in the Control of Innate and Adaptive Immune Responses

(2017) Barbara Frossi et al.   TRENDS IN IMMUNOLOGY

Dynamics of the human gut microbiome in inflammatory bowel disease

(2017) Jonas Halfvarson et al.   Nature Microbiology

The Role of Mast Cells in Bacterial Infection

(2016) Carl-Fredrik Johnzon et al.   AMERICAN JOURNAL OF PATHOLOGY

Protective effects of tranilast on oxazolone-induced rat colitis through a mast cell-dependent pathway

(2016) Hong-Qian Chu et al.   DIGESTIVE AND LIVER DISEASE

Acute infection with the intestinal parasite Trichuris muris has long-term consequences on mucosal mast cell homeostasis and epithelial integrity

(2016) Daniel Sorobetea et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mast cells in gastrointestinal disorders

(2016) Stephan C. Bischoff   EUROPEAN JOURNAL OF PHARMACOLOGY

Mast cell stabilisers

(2016) Tao Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microbes taming mast cells: Implications for allergic inflammation and beyond

(2016) Paul Forsythe   EUROPEAN JOURNAL OF PHARMACOLOGY

Fungal microbiota dysbiosis in IBD

(2016) Harry Sokol et al.   GUT

Mast cells phagocyte Candida albicans and produce nitric oxide by mechanisms involving TLR2 and Dectin-1

(2016) Karen Henriette Pinke et al.   IMMUNOBIOLOGY

Heat-Killed Enterococcus faecalis EF-2001 Ameliorates Atopic Dermatitis in a Murine Model

(2016) Eun-Ju Choi et al.   Nutrients

Live Staphylococcus aureus Induces Expression and Release of Vascular Endothelial Growth Factor in Terminally Differentiated Mouse Mast Cells

(2016) Carl-Fredrik Johnzon et al.   Frontiers in Immunology

The role of mast cells in functional GI disorders

(2015) Mira M Wouters et al.   GUT

Recognition of Candida albicans by Dectin-1 induces mast cell activation

(2015) Alejandro Nieto-Patlán et al.   IMMUNOBIOLOGY

Changes in Epithelial Barrier Function in Response to Parasitic Infection: Implications for IBD Pathogenesis

(2015) J. A. Fernandez-Blanco et al.   Journal of Crohns & Colitis

Opportunistic pathogen Candida albicans elicits a temporal response in primary human mast cells

(2015) José Pedro Lopes et al.   Scientific Reports

Commensal bacteria directly suppressin vitrodegranulation of mast cells in a MyD88-independent manner

(2014) Kazumi Kasakura et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Probiotics and Antibiotics in IBD

(2014) Harry Sokol   DIGESTIVE DISEASES

Mast Cells in Irritable Bowel Syndrome and Ulcerative Colitis: Function Not Numbers Is What Makes All the Difference

(2014) Theoharis C. Theoharides   DIGESTIVE DISEASES AND SCIENCES

Mast cells are activated byStaphylococcus aureus in vitrobut do not influence the outcome of intraperitonealS. aureusinfectionin vivo

(2014) Elin Rönnberg et al.   IMMUNOLOGY

Mast Cells Kill Candida albicans in the Extracellular Environment but Spare Ingested Fungi from Death

(2014) Elisa Trevisan et al.   INFLAMMATION

Does β-Hexosaminidase Function Only as a Degranulation Indicator in Mast Cells? The Primary Role of β-Hexosaminidase in Mast Cell Granules

(2014) Nobuyuki Fukuishi et al.   JOURNAL OF IMMUNOLOGY

Sporothrix schenckii yeasts induce ERK pathway activation and secretion of IL-6 and TNF-α in rat mast cells, but no degranulation

(2014) Yolanda Romo-Lozano et al.   MEDICAL MYCOLOGY

Escherichia coliExposure Inhibits Exocytic SNARE-Mediated Membrane Fusion in Mast Cells

(2014) Jordan Wesolowski et al.   TRAFFIC

Mast Cell Tryptase Reduces Junctional Adhesion Molecule-A (JAM-A) Expression in Intestinal Epithelial Cells: Implications for the Mechanisms of Barrier Dysfunction in Irritable Bowel Syndrome

(2013) Ewa M Wilcz-Villega et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Colonic Mucosal Immune Activity in Irritable Bowel Syndrome: Comparison with Healthy Controls and Patients with Ulcerative Colitis

(2013) Ji Yong Ahn et al.   DIGESTIVE DISEASES AND SCIENCES

Psychological stress and corticotropin-releasing hormone increase intestinal permeability in humans by a mast cell-dependent mechanism

(2013) Tim Vanuytsel et al.   GUT

Salmonella Typhimurium Impedes Innate Immunity with a Mast-Cell-Suppressing Protein Tyrosine Phosphatase, SptP

(2013) Hae Woong Choi et al.   IMMUNITY

Granzyme D Is a Novel Murine Mast Cell Protease That Is Highly Induced by Multiple Pathways of Mast Cell Activation

(2013) Elin Rönnberg et al.   INFECTION AND IMMUNITY

Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

(2013) Ananya Roy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mast Cell-deficient KitW-sh "Sash" Mutant Mice Display Aberrant Myelopoiesis Leading to the Accumulation of Splenocytes That Act as Myeloid-Derived Suppressor Cells

(2013) A. Michel et al.   JOURNAL OF IMMUNOLOGY

Mucosal Permeability and Immune Activation as Potential Therapeutic Targets of Probiotics in Irritable Bowel Syndrome

(2012) Giovanni Barbara et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Mast Cell TLR2 Signaling Is Crucial for Effective Killing of Francisella tularensis

(2012) A. R. Rodriguez et al.   JOURNAL OF IMMUNOLOGY

A Novel Function for SNAP29 (Synaptosomal-Associated Protein of 29 kDa) in Mast Cell Phagocytosis

(2012) Jordan Wesolowski et al.   PLoS One

Combination of Allergic Factors Can Worsen Diarrheic Irritable Bowel Syndrome: Role of Barrier Defects and Mast Cells

(2011) M Vivinus-Nébot et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Mast cell–nerve axis with a focus on the human gut

(2011) Sabine Buhner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Intestinal mast cells in gut inflammation and motility disturbances

(2011) Benedicte Y. De Winter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Soluble Mediators Released from PI-IBS Patients’ Colon Induced Alteration of Mast Cell: Involvement of Reactive Oxygen Species

(2011) Wei Han et al.   DIGESTIVE DISEASES AND SCIENCES

The impact of bacterial infection on mast cell degranulation

(2011) Jordan Wesolowski et al.   IMMUNOLOGIC RESEARCH

Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress

(2010) María Vicario et al.   BRAIN BEHAVIOR AND IMMUNITY

Commensal bacteria promote migration of mast cells into the intestine

(2010) Junichi Kunii et al.   IMMUNOBIOLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions

(2010) Lena Öhman et al.   Nature Reviews Gastroenterology & Hepatology

Essential role for mast cell tryptase in acute experimental colitis

(2010) M. J. Hamilton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mast cell: an evolutionary perspective

(2009) Enrico Crivellato et al.   BIOLOGICAL REVIEWS

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE