Interethnic scaling of fraction unbound of a drug in plasma and volume of distribution: an analysis of extrapolation from Caucasians to Chinese

Challenges and Opportunities With Oncology Drug Development in China

(2018) Gaurav Bajaj et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Nonlinear Protein Binding: Not What You Think

(2018) Amelia N. Deitchman et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Modeling Drug Disposition and Drug–Drug Interactions Through Hypothesis-Driven Physiologically Based Pharmacokinetics: a Reversal Translation Perspective

(2017) Guo-Fu Li et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

A phase I and pharmacokinetic study of afilbercept with FOLFIRI: comparison of Chinese and Caucasian populations

(2017) Jianming Xu et al.   INVESTIGATIONAL NEW DRUGS

Pharmacokinetics, safety, and tolerability of ceftolozane/tazobactam in healthy Japanese, Chinese, and white subjects

(2016) Anthony Aiudi et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Evaluation of the pharmacokinetics and safety of single and multiple ceftaroline fosamil infusions in healthy Chinese and Western subjects

(2015) Li Yang et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Drug Distribution to Human Tissues: Prediction and Examination of the Basic Assumption in In Vivo Pharmacokinetics-Pharmacodynamics (PK/PD) Research

(2015) Patrick Poulin   JOURNAL OF PHARMACEUTICAL SCIENCES

Similarities and Differences in Gastrointestinal Physiology Between Neonates and Adults: a Physiologically Based Pharmacokinetic Modeling Perspective

(2014) Guo Yu et al.   AAPS Journal

Pharmacokinetics and pharmacodynamics of intravenous and inhaled fluticasone furoate in healthy Caucasian and East Asian subjects

(2013) Ann Allen et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Ethnic-Specific In Vitro–In Vivo Extrapolation and Physiologically Based Pharmacokinetic Approaches to Predict Cytochrome P450-Mediated Pharmacokinetics in the Chinese Population: Opportunities and Challenges

(2013) Guo-Fu Li et al.   CLINICAL PHARMACOKINETICS

When is Protein Binding Important?*

(2013) Jules Heuberger et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling

(2012) Guo-fu Li et al.   ACTA PHARMACOLOGICA SINICA

Prediction of Clearance and Volume of Distribution in the Obese from Normal Weight Subjects

(2012) Iftekhar Mahmood   CLINICAL PHARMACOKINETICS

Species Differences in Distribution and Prediction of Human Vss from Preclinical Data

(2011) L. M. Berry et al.   DRUG METABOLISM AND DISPOSITION

Effects of Drug Transporters on Volume of Distribution

(2009) Anita Grover et al.   AAPS Journal

Pharmacokinetics of 8-hour intravenous infusion of NXY-059: A phase I, randomized, double-blind (within dose panels), placebo-controlled study in healthy Chinese volunteers

(2009) Yi-Fang Cheng et al.   CLINICAL THERAPEUTICS

Development of a novel method for predicting human volume of distribution at steady-state of basic drugs and comparative assessment with existing methods

(2009) Patrick Poulin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Role of Ethnicity in Variability in Response to Drugs: Focus on Clinical Pharmacology Studies

(2008) SU Yasuda et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS