Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

Structural and Functional Insights into the Myosin Motor Mechanism

(2010) H. Lee Sweeney et al.   Annual Review of Biophysics

Executive Summary: Heart Disease and Stroke Statistics—2010 Update

(2010) et al.   CIRCULATION

Improvement of Cardiac Function by a Cardiac Myosin Activator in Conscious Dogs With Systolic Heart Failure

(2010) You-Tang Shen et al.   Circulation-Heart Failure

Turning enzymes ON with small molecules

(2010) Julie A Zorn et al.   Nature Chemical Biology

Systolic Heart Failure

(2010) John J.V. McMurray   NEW ENGLAND JOURNAL OF MEDICINE

Discovery of Omecamtiv Mecarbil the First, Selective, Small Molecule Activator of Cardiac Myosin

(2010) Bradley P. Morgan et al.   ACS Medicinal Chemistry Letters

Effects of Cardiac Myosin Isoform Variation on Myofilament Function and Crossbridge Kinetics in Transgenic Rabbits

(2009) Takeki Suzuki et al.   Circulation-Heart Failure

Inotropes in the management of acute heart failure

(2009) John W. Petersen et al.   CRITICAL CARE MEDICINE

Heart Failure Incidence and Survival (from the Atherosclerosis Risk in Communities Study)

(2008) Laura R. Loehr et al.   AMERICAN JOURNAL OF CARDIOLOGY

Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs

(2007) Patricia N. Banfor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY