Prostaglandin E2/EP2 receptor signalling pathway promotes diabetic retinopathy in a rat model of diabetes

Matrine suppresses AGE-induced HAEC injury by inhibiting ROS-mediated NRLP3 inflammasome activation

(2018) Yong Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2Production

(2017) Zbigniew Zasłona et al.   JOURNAL OF IMMUNOLOGY

Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

(2017) Yi Zhang et al.   Cell Death & Disease

The role ofN-glycosylation in high glucose-induced upregulation of intercellular adhesion molecule-1 on bovine retinal endothelial cells

(2016) Kun Liu et al.   ACTA OPHTHALMOLOGICA

Activation of the TXNIP/NLRP3 inflammasome pathway contributes to inflammation in diabetic retinopathy: a novel inhibitory effect of minocycline

(2016) Wei Chen et al.   INFLAMMATION RESEARCH

Prostaglandin E2Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages

(2015) Milena Sokolowska et al.   JOURNAL OF IMMUNOLOGY

CREB pathway links PGE2 signaling with macrophage polarization

(2015) Bing Luan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

(2015) L Baron et al.   Cell Death & Disease

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

(2015) Kevin Monaghan et al.   PLoS One

Mechanism of NLRP3 inflammasome activation

(2014) Fayyaz S. Sutterwala et al.   Annals of the New York Academy of Sciences

Retinopathy in a novel model of metabolic syndrome and type 2 diabetes: new insight on the inflammatory paradigm

(2014) Kousuke Noda et al.   FASEB JOURNAL

Chemokine Mediated Monocyte Trafficking into the Retina: Role of Inflammation in Alteration of the Blood-Retinal Barrier in Diabetic Retinopathy

(2014) Sampathkumar Rangasamy et al.   PLoS One

Disorganization of the Retinal Inner Layers as a Predictor of Visual Acuity in Eyes With Center-Involved Diabetic Macular Edema

(2014) Jennifer K. Sun et al.   JAMA Ophthalmology

Adenosine is required for sustained inflammasome activation via the A2A receptor and the HIF-1α pathway

(2013) Xinshou Ouyang et al.   Nature Communications

The worldwide epidemic of diabetic retinopathy

(2012) Nathan Congdon et al.   INDIAN JOURNAL OF OPHTHALMOLOGY

Diabetic Retinopathy

(2012) David A. Antonetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

GSK-3β/CREB axis mediates IGF-1-induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells: Implications for diabetic retinopathy

(2011) Takhellambam S. Devi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Modulation of T cell immune functions by the prostaglandin E2 - cAMP pathway in chronic inflammatory states

(2011) Kristoffer Watten Brudvik et al.   BRITISH JOURNAL OF PHARMACOLOGY

CHARACTERISTICS OF OPTICAL COHERENCE TOMOGRAPHIC HYPERREFLECTIVE FOCI IN RETINAL VEIN OCCLUSION

(2011) Ken Ogino et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications

(2009) Elisabetta Dejana et al.   DEVELOPMENTAL CELL

Microglial Activation in Human Diabetic Retinopathy

(2008) Hui-yang Zeng   ARCHIVES OF OPHTHALMOLOGY

Diabetic complications and dysregulated innate immunity

(2007) Dana et al.   Frontiers in Bioscience-Landmark