Tissue Regeneration Enhancer Elements: A Way to Unlock Endogenous Healing Power

Ultraconserved Enhancers Are Required for Normal Development

(2018) Diane E. Dickel et al.   CELL

The epicardium as a hub for heart regeneration

(2018) Jingli Cao et al.   Nature Reviews Cardiology

Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer

(2018) Yejing Ge et al.   NATURE REVIEWS GENETICS

Enhancer redundancy provides phenotypic robustness in mammalian development

(2018) Marco Osterwalder et al.   NATURE

The axolotl genome and the evolution of key tissue formation regulators

(2018) Sergej Nowoshilow et al.   NATURE

KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS

(2017) Akintomide Apara et al.   JOURNAL OF NEUROSCIENCE

Characterization of noncoding regulatory DNA in the human genome

(2017) Ran Elkon et al.   NATURE BIOTECHNOLOGY

Limb development: a paradigm of gene regulation

(2017) Florence Petit et al.   NATURE REVIEWS GENETICS

The careg element reveals a common regulation of regeneration in the zebrafish myocardium and fin

(2017) Catherine Pfefferli et al.   Nature Communications

Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program

(2017) Charu Mehta et al.   Cell Reports

The Molecular and Cellular Choreography of Appendage Regeneration

(2016) Elly M. Tanaka   CELL

Progressive Loss of Function in a Limb Enhancer during Snake Evolution

(2016) Evgeny Z. Kvon et al.   CELL

Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution

(2016) Hannah K. Long et al.   CELL

Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration

(2016) Xuxu Sun et al.   Cell Stem Cell

Loss and Re-emergence of Legs in Snakes by Modular Evolution of Sonic hedgehog and HOXD Enhancers

(2016) Francisca Leal et al.   CURRENT BIOLOGY

Zebrafish fin and heart: what's special about regeneration?

(2016) Ivonne M. Sehring et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Modulation of tissue repair by regeneration enhancer elements

(2016) Junsu Kang et al.   NATURE

FGF8 and SHH substitute for anterior–posterior tissue interactions to induce limb regeneration

(2016) Eugeniu Nacu et al.   NATURE

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

(2016) Ingo Braasch et al.   NATURE GENETICS

Epigenomic annotation of gene regulatory alterations during evolution of the primate brain

(2016) Marit W Vermunt et al.   NATURE NEUROSCIENCE

Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs

(2016) Robin E Harris et al.   eLife

Unraveling the Tangled Skein: The Evolution of Transcriptional Regulatory Networks in Development

(2015) Mark Rebeiz et al.   Annual Review of Genomics and Human Genetics

Long-range gene regulation and novel therapeutic applications

(2015) A. van den Heuvel et al.   BLOOD

A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury

(2015) Catherine A. Guenther et al.   BONE

Enhancer Evolution across 20 Mammalian Species

(2015) Diego Villar et al.   CELL

Human-Chimpanzee Differences in a FZD8 Enhancer Alter Cell-Cycle Dynamics in the Developing Neocortex

(2015) J. Lomax Boyd et al.   CURRENT BIOLOGY

Control of tissue growth by Yap relies on cell density and F-actin in zebrafish fin regeneration

(2015) R. Mateus et al.   DEVELOPMENT

Using transgenic reporter assays to functionally characterize enhancers in animals

(2015) Evgeny Z. Kvon   GENOMICS

A large genomic deletion leads to enhancer adoption by the lamin B1 gene: a second path to autosomal dominant adult-onset demyelinating leukodystrophy (ADLD)

(2015) Elisa Giorgio et al.   HUMAN MOLECULAR GENETICS

An orphan gene is necessary for preaxial digit formation during salamander limb development

(2015) Anoop Kumar et al.   Nature Communications

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA

(2015) Nicolas Léveillé et al.   Nature Communications

Identification of the orphan gene Prod 1 in basal and other salamander families

(2015) Jie Geng et al.   EvoDevo

A Remote GATA2 Hematopoietic Enhancer Drives Leukemogenesis in inv(3)(q21;q26) by Activating EVI1 Expression

(2014) Hiromi Yamazaki et al.   CANCER CELL

A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

(2014) Stefan Gröschel et al.   CELL

Differential reparative phenotypes between zebrafish and medaka after cardiac injury

(2014) Kohei Ito et al.   DEVELOPMENTAL DYNAMICS

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

(2014) Daniel Herranz et al.   NATURE MEDICINE

Transcriptional enhancers: from properties to genome-wide predictions

(2014) Daria Shlyueva et al.   NATURE REVIEWS GENETICS

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

(2013) Alex S. Nord et al.   CELL

Reactivating head regrowth in a regeneration-deficient planarian species

(2013) S.-Y. Liu et al.   NATURE

The molecular logic for planarian regeneration along the anterior–posterior axis

(2013) Yoshihiko Umesono et al.   NATURE

Restoration of anterior regeneration in a planarian with limited regenerative ability

(2013) James M. Sikes et al.   NATURE

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Skin shedding and tissue regeneration in African spiny mice (Acomys)

(2012) Ashley W. Seifert et al.   NATURE

C/EBP Transcription Factors Mediate Epicardial Activation During Heart Development and Injury

(2012) G. N. Huang et al.   SCIENCE

Mechanisms of transcriptional precision in animal development

(2012) Mounia Lagha et al.   TRENDS IN GENETICS

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

Regeneration and transdetermination: The role of wingless and its regulation

(2010) Margrit Schubiger et al.   DEVELOPMENTAL BIOLOGY

Evidence for the Local Evolution of Mechanisms Underlying Limb Regeneration in Salamanders

(2010) A. Acely Garza-Garcia et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Regenerative Growth in Drosophila Imaginal Discs Is Regulated by Wingless and Myc

(2009) Rachel K. Smith-Bolton et al.   DEVELOPMENTAL CELL

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

Genetic evidence for shared mechanisms of epimorphic regeneration in zebrafish

(2009) Z. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KLF Family Members Regulate Intrinsic Axon Regeneration Ability

(2009) D. L. Moore et al.   SCIENCE