Transcriptional response to Wnt activation regulates the regenerative capacity of the mammalian cochlea

Sox2 haploinsufficiency primes regeneration and Wnt responsiveness in the mouse cochlea

(2018) Patrick J. Atkinson et al.   JOURNAL OF CLINICAL INVESTIGATION

Stimulation of functional neuronal regeneration from Müller glia in adult mice

(2017) Nikolas L. Jorstad et al.   NATURE

Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells

(2017) Will J. McLean et al.   Cell Reports

The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress

(2016) Xin Mei et al.   ANTIOXIDANTS & REDOX SIGNALING

Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea

(2016) Wenli Ni et al.   JOURNAL OF NEUROSCIENCE

Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea

(2016) Wenli Ni et al.   Oncotarget

Sox2 in the differentiation of cochlear progenitor cells

(2016) Judith S. Kempfle et al.   Scientific Reports

A protein interaction map for cell-cell adhesion regulators identifies DUSP23 as a novel phosphatase for β-catenin

(2016) Lisa Leon Gallegos et al.   Scientific Reports

Comprehensive Expression of Wnt Signaling Pathway Genes during Development and Maturation of the Mouse Cochlea

(2016) Ruishuang Geng et al.   PLoS One

NRF2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea

(2016) Yohei Honkura et al.   Scientific Reports

Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

(2016) Valentina Cappello et al.   Scientific Reports

Molecular cloning and functional characterisation of chicken Atonal homologue 1: A comparison with human Atoh1

(2015) Joanna F. Mulvaney et al.   BIOLOGY OF THE CELL

The Wnt and Notch signalling pathways in the developing cochlea: Formation of hair cells and induction of regenerative potential

(2015) Magdalena Żak et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of  -Catenin and Atoh1

(2015) B. R. Kuo et al.   JOURNAL OF NEUROSCIENCE

Extracellular proteolysis in structural and functional plasticity of mossy fiber synapses in hippocampus

(2015) Grzegorz Wiera et al.   Frontiers in Cellular Neuroscience

The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids

(2015) Mirjana Kessler et al.   Nature Communications

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Wnt–Notch signalling crosstalk in development and disease

(2014) Giovanna M. Collu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo

(2014) B. C. Cox et al.   DEVELOPMENT

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength

(2014) W. de Lau et al.   GENES & DEVELOPMENT

 -Catenin Is Required for Hair-Cell Differentiation in the Cochlea

(2014) F. Shi et al.   JOURNAL OF NEUROSCIENCE

Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms

(2014) Rob Patro et al.   NATURE BIOTECHNOLOGY

Expression and Replication Studies to Identify New Candidate Genes Involved in Normal Hearing Function

(2014) Giorgia Girotto et al.   PLoS One

Using Multi-Instance Hierarchical Clustering Learning System to Predict Yeast Gene Function

(2014) Bo Liao et al.   PLoS One

Dynamic regulation of genome-wide pre-mRNA splicing and stress tolerance by the Sm-like protein LSm5 in Arabidopsis

(2014) Peng Cui et al.   GENOME BIOLOGY

Long-term Time Lapse Imaging of Mouse Cochlear Explants

(2014) Joanna F. Mulvaney et al.   Jove-Journal of Visualized Experiments

Lgr5-Positive Supporting Cells Generate New Hair Cells in the Postnatal Cochlea

(2014) Naomi F. Bramhall et al.   Stem Cell Reports

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors

(2013) Shuhei Watanabe et al.   JOURNAL OF GASTROENTEROLOGY

Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors

(2013) Fuxin Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch signaling during cell fate determination in the inner ear

(2013) Amy E. Kiernan   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Qualimap: evaluating next-generation sequencing alignment data

(2012) Fernando García-Alcalde et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A dual function for canonical Wnt/ -catenin signaling in the developing mammalian cochlea

(2012) B. E. Jacques et al.   DEVELOPMENT

EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals

(2012) Patricia M. White et al.   DEVELOPMENTAL BIOLOGY

Secreted Factor R-Spondin 2 is Involved in Refinement of Patterning of the Mammalian Cochlea

(2012) J. F. Mulvaney et al.   DEVELOPMENTAL DYNAMICS

Wnt-Responsive Lgr5-Expressing Stem Cells Are Hair Cell Progenitors in the Cochlea

(2012) F. Shi et al.   JOURNAL OF NEUROSCIENCE

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

(2012) R. Chai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice

(2011) Katrin Arnold et al.   Cell Stem Cell

Notch Signaling Alters Sensory or Neuronal Cell Fate Specification of Inner Ear Stem Cells

(2011) S.-J. Jeon et al.   JOURNAL OF NEUROSCIENCE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Prediction of microRNAs affecting mRNA expression during retinal development

(2010) Amit Arora et al.   BMC DEVELOPMENTAL BIOLOGY

Genome-wide identification of new Wnt/β-catenin target genes in the human genome using CART method

(2010) Christian Hödar et al.   BMC GENOMICS

Genomic response to Wnt signalling is highly context-dependent — Evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets

(2009) Antti Railo et al.   EXPERIMENTAL CELL RESEARCH

BBS7andTTC8(BBS8) mutations play a minor role in the mutational load of Bardet-Biedl syndrome in a multiethnic population

(2009) Jenea Bin et al.   HUMAN MUTATION

Interplay of Cadherin-Mediated Cell Adhesion and Canonical Wnt Signaling

(2009) J. Heuberger et al.   Cold Spring Harbor Perspectives in Biology

Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode

(2008) C. S. Jayasena et al.   DEVELOPMENT