Review
Food Science & Technology
Xuxiao Gong, Qi An, Liqing Le, Fang Geng, Liangzhen Jiang, Jun Yan, Dabing Xiang, Lianxin Peng, Liang Zou, Gang Zhao, Yan Wan
Summary: Cereal protein peptides have various functional properties and can be used as antioxidants, antibacterials, anti-inflammatories, and anticancer agents, with the potential to lower blood pressure, control blood sugar, and inhibit thrombosis. The functional properties of peptides derived from different cereal proteins vary, which may be related to the amino acid composition and protein types of the cereals. Bioinformatics combined with experimental verification can be used to study the structure-activity relationship of bioactive peptides in depth.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Dandan Liu, Yiting Guo, Haile Ma
Summary: This review provides an overview of the current research status of bioactive peptides derived from walnut by-products. The review covers the preparation, separation, purification, identification, bioactivities, and bioavailability of these peptides. It highlights the various biological activities exhibited by walnut peptides, including antioxidative, antihypertensive, neuroprotective, antidiabetic, anticancer, and antihyperuricemia activities. The review also emphasizes the need for further research in improving the bioavailability of walnut peptides and exploring their molecular mechanisms. Digestion, absorption, and metabolism processes of walnut peptides are also identified as important areas for future research.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Agronomy
Jessica Paranhos, Wheeler Foshee, Timothy Coolong, Brian Heyes, Melba Salazar-Gutierrez, Kathelyn Kesheimer, Andre Luiz Biscaia Ribeiro da Silva
Summary: This study evaluated the performance of ten commercial sweet corn cultivars under various environmental conditions in the southeastern U.S. and described the impacts of weather variability on cultivar development, yield, and ear quality. The daily air temperature in spring and fall had the greatest influence on yield and ear quality, with spring having a longer growing season and higher yield. The cultivars with the most potential against environmental stresses and best performance were Affection, GSS1170, Passion, and SCI336 in spring, and Affection, GSS1170, and SC1136 in fall.
Review
Food Science & Technology
Brij Pal Singh, Sneh Punia Bangar, Munira Alblooshi, Feyisola Fisayo Ajayi, Priti Mudgil, Sajid Maqsood
Summary: The development of plant proteins as sustainable alternatives to traditional animal proteins is a major challenge in the agri-food industry. Plant proteins not only serve as a sustainable source of protein, but also have functional and health-promoting properties due to active peptides. This review comprehensively discusses the importance of plant-based proteins, their production and characterization, and the bioactivities and bioavailability of plant protein-derived bioactive peptides.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Ayse Gulden Goksu, Bilal Cakir, Ibrahim Gulseren
Summary: Cold press hazelnut cakes can be used as a concentrated source of proteins that have bioactive properties. Utilizing bioactive hazelnut protein hydrolysates in industrial hazelnut cocoa cream and investigating their stability through processing and simulated gastrointestinal digestion showed that the inclusion of bioactive peptide fractions was safe and improved the bioactive attributes of the products.
FOOD RESEARCH INTERNATIONAL
(2022)
Review
Food Science & Technology
Narasimha Kumar Kopparapu, Yajie Duan, Linhua Huang, Priti Katrolia
Summary: Food wastage is a pressing global issue that needs immediate attention. Utilizing by-products and converting them into value-added products can contribute to a sustainable economy. This review focuses on the modification of corn gluten meal (CGM) and its potential applications in food and other industries.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Cell Biology
Evgeniya Trofimenko, Yuta Homma, Mitsunori Fukuda, Christian Widmann
Summary: Endocytosis and endosome dynamics are regulated by small GTPase Rab proteins. Besides the known endocytic pathways, a Rab14-dependent pathway has been identified that moves material to nonacidic late endosomes. This pathway is distinct from conventional Rab5-dependent endocytosis and is not affected by inhibitors of macropinocytosis or clathrin-mediated endocytosis.
Article
Biochemistry & Molecular Biology
Baojie Dou, Xudong Wu, Zihan Xia, Guanghao Wu, Quanyou Guo, Mingsheng Lyu, Shujun Wang
Summary: In this study, alkaline protease was used to hydrolyze loach, and different molecular weight hydrolysates were obtained. The <3 kDa fraction showed the strongest antioxidant activity, and six peptides with antioxidant and enzyme inhibition activities were identified. These results provide a basis for the nutritional value and development of healthy loach products.
Article
Food Science & Technology
Shumao Cui, Zheming Gu, Wenli Wang, Xin Tang, Qiuxiang Zhang, Bingyong Mao, Hao Zhang, Jianxin Zhao
Summary: This study analyzed the rules of peptide utilization in different bifidobacteria and found that bifidobacteria have a high affinity for hydrophilic peptides containing growth-promoting amino acids. The quantity and preference of transportable peptides varied among different strains. Genome sequence analysis revealed significant differences in amino acid and peptide transport systems. The study highlights the importance of specific peptides as nitrogen sources for the growth of bifidobacteria.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Cell Biology
Hamid Lotfimehr, Narges Mardi, Samaneh Narimani, Hamid Tayefi Nasrabadi, Mohammad Karimipour, Emel Sokullu, Reza Rahbarghazi
Summary: The protein kinase called mammalian target of rapamycin (mTOR) responds to various stimuli and can influence cell growth, metabolism, and other bioactivities. This study explores the relationship between the mTOR signaling pathway and the regenerative potential of stem cells, particularly in terms of angiogenesis. The findings suggest that modulating mTOR signaling pathways could be an effective strategy for manipulating the angiogenic properties of stem cells.
CELL PROLIFERATION
(2023)
Review
Food Science & Technology
Tolulope Joshua Ashaolu, Itthanan Suttikhana
Summary: The increasing global demand for green and sustainable food sources has led to a preference for plant-based foods over animal-based products. Plant-based bioactive peptides (BPs) have been shown to have numerous health-promoting qualities. This review explores the demonstrated in vivo bioactivities of plant-based BPs, including their production, biological effects, and mechanisms of action. The potential therapeutic and commercialization prospects of these BPs are also discussed.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Marta Fernandez Cunha, Ezequiel R. Coscueta, Maria Emilia Brassesco, Rita Marques, Jose Neto, Frederico Almada, David Goncalves, Manuela Pintado
Summary: Identifying bioactive molecules from marine organisms, particularly fish like the Lusitanian toadfish, can lead to the discovery of potential antioxidants, antihypertensives, and antimicrobial agents. The peptide fraction of the fish's body mucus was characterized, showing promising bioactive properties with potential applications in the food and pharmaceutical industries.
Article
Food Science & Technology
Zhicui Yao, Shiming Song, Xiaoling Li, Wentao Wang, Peng Ren, Haiyue Wang, Ying Xie, Zengning Li
Summary: The study shows that corn peptides have antioxidant and detoxifying effects in vivo and in vitro models, and improve lipid metabolism by activating the AMPK alpha/Sirt1 pathway. This suggests that corn peptides could be a promising functional food for preventing nonalcoholic fatty liver disease.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Review
Fisheries
Lili Hao, Xincen Wang, Yunrui Cao, Jie Xu, Changhu Xue
Summary: Oysters are a healthy source of lean protein and the polypeptides extracted from oyster protein have diverse bioactivities. However, challenges remain in the preparation and characterisation of oyster polypeptides. Research efforts are needed to optimize hydrolysis conditions and identify the amino acid sequence and structure of oyster peptides for potential development of more efficient and safer products.
REVIEWS IN AQUACULTURE
(2022)
Article
Food Science & Technology
Xiao Ke, Xiao Hu, Laihao Li, Xianqing Yang, Shengjun Chen, Yanyan Wu, Changhu Xue
Summary: The study showed that tilapia skin collagen hydrolysates have high zinc-binding capacity, with GFLGSP exhibiting the best performance. The zinc-binding sites of peptide GFLGSP were located at the nitrogen atom of the amino group and the oxygen atom of the carboxyl group. Additionally, GFLGSP demonstrated stability during simulated gastrointestinal digestion and could be transported through the paracellular pathway via tight junctions.
Review
Food Science & Technology
Danjun Guo, Mengge Zhao, Wei Xu, Hui He, Bin Li, Tao Hou
Summary: Osteoporosis is a significant public health concern, but dietary interventions can help prevent and reverse bone loss. Nutrients from daily diets and dietary patterns play critical roles in skeletal health.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Mengge Zhao, Aimin Ma, Hui He, Xing Zhang, Lei Jia, Tao Hou
Summary: Two novel calcium delivery systems prepared with desalted duck egg white peptides and chitosan oligosaccharide showed high calcium-binding ability and improved gut health by inhibiting the proliferation of Escherichia coli and promoting the growth of beneficial bacteria. The calcium delivery systems also increased short chain fatty acids production and improved boundary membrane function, suggesting their superior performance compared to commercially available calcium supplements.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Haitao Li, Xiaoyan Chen, Yan Guo, Tao Hou, Jun Hu
Summary: Enzymatic hydrolysis of salted duck egg white produced ACE inhibitory peptides. The optimal hydrolysis conditions were determined to be enzyme dosage of 11875.99 U/g, substrate concentration of 33.04 g/L, and hydrolysis time of 4 hours. The study identified and synthesized peptides that exhibited strong ACE inhibitory activity, with Ile-Leu-Lys-Pro showing the highest activity. Molecular docking analysis revealed important binding sites and amino acids contributing to the stability of the docking complex.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Mengge Zhao, Hui He, Aimin Ma, Tao Hou
Summary: Covalent interactions between proteins/peptides and saccharides have been gaining increasing attention due to their enhanced functional attributes, such as better gelling property, thermostability, and water-holding capacity. Food-derived protein/peptide-saccharide covalent conjugates (PSCCs) are widely used in the functional food industry and possess various biological activities.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Mengge Zhao, Hui He, Danjun Guo, Xing Zhang, Lei Jia, Tao Hou, Aimin Ma
Summary: The novel TPP-COS/DPs-Ca microcapsules demonstrated potential in controlled release, promoting calcium absorption, and improving gut health in vitro and vivo. They could effectively reduce the risk of osteoporosis by enhancing calcium absorption and gut health.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Nutrition & Dietetics
Guo Liu, Jun Zhang, Qixin Kan, Mingyue Song, Tao Hou, Siyu An, Hongyu Lin, Hongzhang Chen, Liuyun Hu, Jie Xiao, Yunjiao Chen, Yong Cao
Summary: Ganoderma lucidum polysaccharides (GLP) have excellent immunomodulatory activity. Among them, the high molecular weight Restriction Fragment Length Polymorphism (RGLP) exhibits stronger immunomodulatory activity than the low molecular weight EGLP. Structural analysis reveals that RGLP-1 is a β-pyran polysaccharide with specific glycosyl bonds, showing potential immunomodulatory properties.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Applied
Xing Zhang, Lei Jia, Hui He, Hongqing Yin, Jiajia Ming, Tao Hou, Jiqian Xiang
Summary: This study investigated the antioxidant properties of Se-containing peptides from Cardamine enshiensis (SeCPPs) and their impact on gut microbiota. The results showed that SeCPPs had a significant antioxidant effect and could modulate the gut microbiome in mice. In addition, SeCPPs improved memory in aging mice and reduced Proteobacteria and Akkermansia abundances in antibiotic-treated mice.
Editorial Material
Nutrition & Dietetics
Tao Hou
FRONTIERS IN NUTRITION
(2022)
Review
Food Science & Technology
Shan Zhang, Yashu Chen, David Julian McClements, Tao Hou, Fang Geng, Peng Chen, Hongjian Chen, Bijun Xie, Zhida Sun, Hu Tang, Yaqiong Pei, Shuang Quan, Xiao Yu, Qianchun Deng
Summary: This paper summarizes and analyzes the limitations and challenges of incorporating whole flaxseed (flour) into fortified food products, as well as its potential influences on food matrix and edibility. The potential influencing mechanisms of flaxseed (flour) on different substrate components are investigated, and possible solutions against negative impacts are proposed. Overall, this paper provides useful information for expanding the application of whole flaxseed (flour) based on optimal edibility and nutritional properties of fortified food products.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Review
Food Science & Technology
Pengkui Xia, Tao Hou, Hong Jin, Yaqi Meng, Jing Li, Fuchao Zhan, Fang Geng, Bin Li
Summary: This review provides a comprehensive overview of the risk factors regulating the intestinal microenvironment in IBD and discusses five protective pathways related to the gut microbiota. It aims to offer insights for the treatment of IBDs and theoretical guidance for personalized precision nutrition for patients.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Mengge Zhao, Boyuan Li, Hui He, Tao Hou
Summary: The present study aimed to extract antioxidative peptides from Lumbricus protein and investigate their bioavailability and preventive effects against UV-B radiation-induced skin damage. The results showed that these peptides could effectively inhibit skin oxidative stress and regulate the expression and distribution of Bcl-2 and Bax. Molecular docking analysis also identified peptides with high binding affinities, suggesting the potential application of Lumbricus protein as a natural antioxidant.
Review
Food Science & Technology
Yuan Wan, Qiaoyun Zhou, Mengge Zhao, Tao Hou
Summary: Sesame is mainly used for oil production, but the byproduct sesame meal is often wasted. Sesame meal is rich in sesame protein and three types of sesame lignans, which can be extracted and used as protein source and for their various biological activities. This review summarizes the extraction methods and functional activities of sesame protein and lignans in sesame meal, aiming to provide theoretical guidance for its maximum utilization.
Article
Biochemistry & Molecular Biology
Pengkui Xia, Xia Liu, Tao Hou, Fuchao Zhan, Fang Geng, Ziyang Zhang, Bin Li
Summary: This study found that prebiotic sesame sugar (PSC) can alleviate the symptoms of constipation and improve defecation function and intestinal motility. Furthermore, PSC can also repair gastrointestinal tissue damage and inflammation caused by constipation.
Article
Biochemistry & Molecular Biology
Pengkui Xia, Tao Hou, Muyuan Ma, Sha Li, Hong Jin, Xuan Luo, Jing Li, Fang Geng, Bin Li
Summary: This study found that konjac oligosaccharides (KOS) have a protective effect on colitis mice. KOS treatment can reduce pathological damage to colon tissues, increase the expression of tight junction proteins, regulate the composition of gut microbiota, and down-regulate pro-inflammatory bacteria while up-regulating anti-inflammatory bacteria.
Article
Biochemistry & Molecular Biology
Xing Zhang, Hui He, Jiqian Xiang, Tao Hou
Summary: Our study evaluated the potential of selenium-containing peptides in terms of antioxidant activity, safety, and bioavailability. We identified the peptide sequence SFQSeM as a promising candidate with strong antioxidant effects, stability in the gastrointestinal tract, and low impact on liver health. SFQSeM has the potential to be an effective selenium nutritional supplement.
