The value of zebrafish as an integrative model in effect-directed analysis - a review

Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos

(2014) Eva Fetter et al.   AQUATIC TOXICOLOGY

PAH toxicity at aqueous solubility in the fish embryo test with Danio rerio using passive dosing

(2014) Thomas-Benjamin Seiler et al.   CHEMOSPHERE

A novel contact assay for testing aryl hydrocarbon receptor (AhR)-mediated toxicity of chemicals and whole sediments in zebrafish (Danio rerio) embryos

(2014) Sabrina Schiwy et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Development of a Highly Visual, Simple, and Rapid Test for the Discovery of Novel Insulin Mimetics in Living Vertebrates

(2013) Jinho Lee et al.   ACS Chemical Biology

Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models

(2013) Olivia Erin Buenafe et al.   ACS Chemical Neuroscience

In vitro and in vivo antioxidant activities of polysaccharide purified from aloe vera (Aloe barbadensis) gel

(2013) Min-Cheol Kang et al.   CARBOHYDRATE POLYMERS

Zebrafish: A Multifaceted Tool for Chemical Biologists

(2013) Sandeep Basu et al.   CHEMICAL REVIEWS

Acute toxicity of aromatic and non-aromatic fractions of naphthenic acids extracted from oil sands process-affected water to larval zebrafish

(2013) A.G. Scarlett et al.   CHEMOSPHERE

Effects-directed analysis (EDA) and toxicity identification evaluation (TIE): Complementary but different approaches for diagnosing causes of environmental toxicity

(2013) Robert M. Burgess et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Molecular mechanisms of angiogenesis effect of active sub-fraction from root of Rehmannia glutinosa by zebrafish sprout angiogenesis-guided fractionation

(2013) Cheuk-Lun Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Development of a seaweed derived platelet activating factor acetylhydrolase (PAF-AH) inhibitory hydrolysate, synthesis of inhibitory peptides and assessment of their toxicity using the Zebrafish larvae assay

(2013) Ciarán Fitzgerald et al.   PEPTIDES

Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products

(2013) Nadine Bohni et al.   PLoS One

Optimization and Pharmacological Validation of a Leukocyte Migration Assay in Zebrafish Larvae for the Rapid In Vivo Bioactivity Analysis of Anti-Inflammatory Secondary Metabolites

(2013) María Lorena Cordero-Maldonado et al.   PLoS One

A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling

(2013) Evelien Gebruers et al.   PLoS One

Mapping of Zebrafish Research: A Global Outlook

(2013) Priyamvadah Kinth et al.   Zebrafish

EDA-EMERGE: an FP7 initial training network to equip the next generation of young scientists with the skills to address the complexity of environmental contamination with emerging pollutants

(2013) Werner Brack et al.   Environmental Sciences Europe

Studying the effects of genistein on gene expression of fish embryos as an alternative testing approach for endocrine disruption

(2012) Viktoria Schiller et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Chondroitin Fragments Are Odorants that Trigger Fear Behavior in Fish

(2012) Ajay S. Mathuru et al.   CURRENT BIOLOGY

The zebrafish issue of Development

(2012) C. Nusslein-Volhard   DEVELOPMENT

Predicting Adult Fish Acute Lethality with the Zebrafish Embryo: Relevance of Test Duration, Endpoints, Compound Properties, and Exposure Concentration Analysis

(2012) Melanie Knöbel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect-directed analysis

(2012) Eric Higley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish and mouse seizure models

(2012) Adriana Monserrath Orellana-Paucar et al.   EPILEPSY & BEHAVIOR

Tracking antiangiogenic components from Glycyrrhiza uralensisFisch. based on zebrafish assays using high-speed countercurrent chromatography

(2012) Liwen Han et al.   JOURNAL OF SEPARATION SCIENCE

Polymethoxy-1-alkenes from Aphanizomenon ovalisporum Inhibit Vertebrate Development in the Zebrafish (Danio rerio) Embryo Model

(2012) Asha Jaja-Chimedza et al.   Marine Drugs

Zebrafish as potential model for developmental neurotoxicity testing

(2012) Celine de Esch et al.   NEUROTOXICOLOGY AND TERATOLOGY

A combined DNA-microarray and mechanism-specific toxicity approach with zebrafish embryos to investigate the pollution of river sediments

(2012) Thomas Kosmehl et al.   REPRODUCTIVE TOXICOLOGY

A Unifying Review of Bioassay-Guided Fractionation, Effect-Directed Analysis and Related Techniques

(2012) Michael G. Weller   SENSORS

Effect-Based Tools for Monitoring and Predicting the Ecotoxicological Effects of Chemicals in the Aquatic Environment

(2012) Richard E. Connon et al.   SENSORS

Behavioral profiling of zebrafish embryos exposed to a panel of 60 water-soluble compounds

(2011) Shaukat Ali et al.   BEHAVIOURAL BRAIN RESEARCH

Poly-ethers from Winogradskyella poriferorum: Antifouling potential, time-course study of production and natural abundance

(2011) Swagatika Dash et al.   BIORESOURCE TECHNOLOGY

Use of TIE techniques to characterize industrial effluents in the Pearl River Delta region

(2011) Yi-Xiang Fang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effect-Directed Analysis of Municipal Landfill Soil Reveals Novel Developmental Toxicants in the ZebrafishDanio rerio

(2011) Juliette Legler et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bioassay-guided isolation of norviburtinal from the root of Rehmannia glutinosa, exhibited angiogenesis effect in zebrafish embryo model

(2011) Cheuk-Lun Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Zebrafish Bioassay-Guided Natural Product Discovery: Isolation of Angiogenesis Inhibitors from East African Medicinal Plants

(2011) Alexander D. Crawford et al.   PLoS One

High-Throughput Screening of Australian Marine Organism Extracts for Bioactive Molecules Affecting the Cellular Storage of Neutral Lipids

(2011) James Rae et al.   PLoS One

Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations

(2011) Uwe Strähle et al.   REPRODUCTIVE TOXICOLOGY

Adverse Outcome Pathways during Early Fish Development: A Conceptual Framework for Identification of Chemical Screening and Prioritization Strategies

(2011) David C. Volz et al.   TOXICOLOGICAL SCIENCES

Induced thyme product prevents VEGF-induced migration in human umbilical vein endothelial cells

(2010) Diane Krill et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Black Carbon Inclusive Multichemical Modeling of PBDE and PCB Biomagnification and -Transformation in Estuarine Food Webs

(2010) Carolina Di Paolo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The versatile, changing, and advancing roles of fish in sediment toxicity assessment—a review

(2010) Arnold V. Hallare et al.   JOURNAL OF SOILS AND SEDIMENTS

DanTox—a novel joint research project using zebrafish (Danio rerio) to identify specific toxicity and molecular modes of action of sediment-bound pollutants

(2010) Steffen Keiter et al.   JOURNAL OF SOILS AND SEDIMENTS

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

(2010) David Kokel et al.   Nature Chemical Biology

Toxicity assessment of sequential leachates of tire powder using a battery of toxicity tests and toxicity identification evaluations

(2009) Anna Wik et al.   CHEMOSPHERE

Effect-Directed Analysis of Contaminated Sediments with Partition-Based Dosing Using Green Algae Cell Multiplication Inhibition

(2009) Nicole Bandow et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effect-directed analysis (EDA) in aquatic ecotoxicology: state of the art and future challenges

(2009) Markus Hecker et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Ichthyotoxic brominated diphenyl ethers from a mixed assemblage of a red alga and cyanobacterium: Structure clarification and biological properties

(2009) Takashi L. Suyama et al.   TOXICON

Antiangiogenic activity of Tripterygium wilfordii and its terpenoids

(2008) Ming-Fang He et al.   JOURNAL OF ETHNOPHARMACOLOGY