4“-O-Alkylated α-Galactosylceramide Analogues as i NKT-Cell Antigens: Synthetic, Biological, and Structural Studies

Solubilization of α-galactosylceramide in aqueous medium: Impact on Natural Killer T cell activation and antitumor responses

(2017) Elodie Macho-Fernandez et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Structural determination of lipid antigens captured at the CD1d–T-cell receptor interface

(2017) Patrick J. Brennan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues

(2017) Jonas Janssens et al.   ACS Medicinal Chemistry Letters

Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation

(2016) Tai-Na Wu et al.   ACS Chemical Biology

Synthesis of C-5″ and C-6″-modified α-GalCer analogues as i NKT-cell agonists

(2015) Joren Guillaume et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and Activity of 6″-Deoxy-6″-thio-α-GalCer and Peptide Conjugates

(2015) Benjamin J. Compton et al.   ORGANIC LETTERS

Design and synthesis of galactose-6-OH-modified α-galactosyl ceramide analogues with Th2-biased immune responses

(2014) Jung-Tung Hung et al.   RSC Advances

Synthesis of 6″-triazole-substituted α-GalCer analogues as potent iNKT cell stimulating ligands

(2012) Nora Pauwels et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New CD1d agonists: Synthesis and biological activity of 6″-triazole-substituted α-galactosyl ceramides

(2012) Peter J. Jervis et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Evaluation of Acyl-Chain- and Galactose-6′′-Modified Analogues of α-GalCer for NKT Cell Activation

(2012) Ming-Han Hsieh et al.   CHEMBIOCHEM

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex

(2012) Kwok S. Wun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

(2011) Sandrine Aspeslagh et al.   EMBO JOURNAL

A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells

(2011) Kwok S. Wun et al.   IMMUNITY

Divergent synthetic approach to 6′′-modified α-GalCer analogues

(2011) Nora Pauwels et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The stimulating adventure of KRN 7000

(2011) Aline Banchet-Cadeddu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Introduction of aromatic group on 4′-OH of α-GalCer manipulated NKT cell cytokine production

(2010) Wenpeng Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode

(2010) Yali Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

(2009) William C Florence et al.   EMBO JOURNAL

Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

(2009) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR

(2008) Kwok S. Wun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

6′-Derivatised α-GalCer Analogues Capable of Inducing Strong CD1d-Mediated Th1-Biased NKT Cell Responses in Mice

(2008) Matthias Trappeniers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population

(2008) J. M. Coquet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RCAI-61, the 6′-O-methylated analog of KRN7000: its synthesis and potent bioactivity for mouse lymphocytes to produce interferon-γ in vivo

(2008) Takuya Tashiro et al.   TETRAHEDRON LETTERS