Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway

The role of nuclear factor erythroid 2-related factor 2 in hepatoprotective activity of natural products: A review

(2018) Milad Iranshahy et al.   FOOD AND CHEMICAL TOXICOLOGY

Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling

(2018) Weiche Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Natural activators of adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) and their pharmacological activities

(2018) Mahdi Vazirian et al.   FOOD AND CHEMICAL TOXICOLOGY

Sodium butyrate induces autophagy in colorectal cancer cells through LKB1/AMPK signaling

(2018) Shunli Luo et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Methyleugenol protects against t -BHP-triggered oxidative injury by induction of Nrf2 dependent on AMPK/GSK3β and ERK activation

(2017) Junfeng Zhou et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

EX4 stabilizes and activates Nrf2 via PKCδ, contributing to the prevention of oxidative stress-induced pancreatic beta cell damage

(2017) Mi-Hwi Kim et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy

(2017) Dongwei Xu et al.   Cell Death & Disease

Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis

(2017) Hongming Lv et al.   Redox Biology

Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway

(2016) Yi-ming Jiang et al.   ACTA PHARMACOLOGICA SINICA

Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity

(2016) Kuo Du et al.   ARCHIVES OF TOXICOLOGY

Nrf2-mediated liver protection by esculentoside A against acetaminophen toxicity through the AMPK/Akt/GSK3β pathway

(2016) Lidong Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

(2016) Dushani L. Palliyaguru et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550

(2016) Min Sung Joo et al.   MOLECULAR AND CELLULAR BIOLOGY

Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

(2016) Kuo Du et al.   Redox Biology

Withaferin-A Reduces Acetaminophen-Induced Liver Injury in Mice

(2015) Ravirajsinh N. Jadeja et al.   BIOCHEMICAL PHARMACOLOGY

Acetaminophen: Dose-Dependent Drug Hepatotoxicity and Acute Liver Failure in Patients

(2015) Hartmut Jaeschke   DIGESTIVE DISEASES

Glycycoumarin ameliorates alcohol-induced hepatotoxicity via activation of Nrf2 and autophagy

(2015) Xinhua Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidative and Antiinflammatory Activities of Asiatic Acid, Glycyrrhizic Acid, and Oleanolic Acid in Human Bronchial Epithelial Cells

(2015) Shih-ming Tsao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Protective effect of oroxylin A against lipopolysaccharide and/or D-galactosamine–induced acute liver injury in mice

(2015) Haiying Huang et al.   JOURNAL OF SURGICAL RESEARCH

The Loss of Cellular Junctions in Epithelial Lung Cells Induced by Cigarette Smoke Is Attenuated by Corilagin

(2015) Ximena M. Muresan et al.   Oxidative Medicine and Cellular Longevity

Anti-inflammatory and anti-oxidative effects of corilagin in a rat model of acute cholestasis

(2013) Feng Jin et al.   BMC GASTROENTEROLOGY

Acetaminophen-related Hepatotoxicity

(2013) Chalermrat Bunchorntavakul et al.   Clinics in Liver Disease

Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways

(2013) Behnam Saberi et al.   HEPATOLOGY

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

(2013) Hemant Kumar et al.   NATURAL PRODUCT REPORTS

Nrf2: A Potential Target for New Therapeutics in Liver Disease

(2012) A M Bataille et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Therapeutic potential ofMoringa oleiferaextracts against acetaminophen-induced hepatotoxicity in rats

(2012) Syazana Akmal Sharifudin et al.   PHARMACEUTICAL BIOLOGY

Isolation and characterization of ellagitannins as the major polyphenolic components of Longan (Dimocarpus longan Lour) seeds

(2012) Yuttana Sudjaroen et al.   PHYTOCHEMISTRY

Current issues with acetaminophen hepatotoxicity—A clinically relevant model to test the efficacy of natural products

(2011) Hartmut Jaeschke et al.   LIFE SCIENCES

Corilagin prevents tert-butyl hydroperoxide-induced oxidative stress injury in cultured N9 murine microglia cells

(2011) Yiyan Chen et al.   NEUROCHEMISTRY INTERNATIONAL

Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: Modulation by the Nrf2/Trx axis

(2010) Mireia Niso-Santano et al.   FREE RADICAL BIOLOGY AND MEDICINE

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity

(2010) Chieko Saito et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Resolution of inflammation-related apoptotic processes by the synthetic tellurium compound, AS101 following liver injury

(2009) Miri Brodsky et al.   JOURNAL OF HEPATOLOGY

Preliminary exploration on anti-inflammatory mechanism of Corilagin (beta-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose) in vitro

(2008) Lei Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Complex Intersection of Inflammation and Oxidation

(2008) Stephen J. Nicholls   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY