Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations

标题

Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations

作者

关键词

G protein-coupled receptor, GPCR, angiotensin II type 1 receptor, angiotensin receptor blocker, ARB, biased agonism, functional selectivity, double electron-electron resonance spectroscopy, DEER, molecular dynamics simulations, conformational selection, beta-arrestin, heterotrimeric G protein

出版物

CELL

Volume -, Issue -, Pages -

出版商

Elsevier BV

发表日期

2019-01-11

DOI

10.1016/j.cell.2018.12.005