Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons
Authors
Keywords
Amyloid Precursor Protein, Dendritic Spine, Primary Neuron, Recycling Endosome, Amyloid Precursor Protein Expression
Journal
Acta Neuropathologica Communications
Volume 3, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-08-20
DOI
10.1186/s40478-015-0230-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β
- (2015) Keith A. Vossel et al. JOURNAL OF CELL BIOLOGY
- Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer–treated hippocampal neurons
- (2015) Kathlyn J. Gan et al. MOLECULAR BIOLOGY OF THE CELL
- Tau acts as a mediator for Alzheimer's disease-related synaptic deficits
- (2014) Dezhi Liao et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Mitochondrial trafficking and anchoring in neurons: New insight and implications
- (2014) Zu-Hang Sheng JOURNAL OF CELL BIOLOGY
- Aβ Influences Cytoskeletal Signaling Cascades with Consequences to Alzheimer’s Disease
- (2014) Ana Gabriela Henriques et al. MOLECULAR NEUROBIOLOGY
- Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-β oligomers and no plaque pathology
- (2014) Katherine A Price et al. Molecular Neurodegeneration
- Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease
- (2014) Shichun Tu et al. Molecular Neurodegeneration
- Alzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function
- (2014) Csilla Ari et al. NEUROBIOLOGY OF AGING
- The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
- (2014) Tara L. Spires-Jones et al. NEURON
- Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation
- (2014) Sandra Maday et al. NEURON
- Amyloid-β and Tau
- (2014) George S. Bloom JAMA Neurology
- Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders
- (2013) Kwok-On Lai et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- β-Amyloid (Aβ) Oligomers Impair Brain-derived Neurotrophic Factor Retrograde Trafficking by Down-regulating Ubiquitin C-terminal Hydrolase, UCH-L1
- (2013) Wayne W. Poon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Actin filaments and microtubules in dendritic spines
- (2013) Tomoaki Shirao et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons
- (2013) H. Decker et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons
- (2013) Elisa M. Ramser et al. MOLECULAR BIOLOGY OF THE CELL
- BDNF mechanisms in late LTP formation: A synthesis and breakdown
- (2013) Debabrata Panja et al. NEUROPHARMACOLOGY
- The entorhinal cortex and neurotrophin signaling in Alzheimer’s disease and other disorders
- (2013) Helen E. Scharfman et al. Cognitive Neuroscience
- Mitochondrial Trafficking in Neurons
- (2013) T. L. Schwarz Cold Spring Harbor Perspectives in Biology
- Synaptic Activity and Bioenergy Homeostasis: Implications in Brain Trauma and Neurodegenerative Diseases
- (2013) Natasha Khatri et al. Frontiers in Neurology
- Aging brain microenvironment decreases hippocampal neurogenesis through Wnt-mediated survivin signaling
- (2012) Carlos J. Miranda et al. AGING CELL
- The Ca2+ and Rho GTPase signaling pathways underlying activity-dependent actin remodeling at dendritic spines
- (2012) Takeo Saneyoshi et al. Cytoskeleton
- Distinct Dendritic Spine and Nuclear Phases of Calcineurin Activation after Exposure to Amyloid- Revealed by a Novel Fluorescence Resonance Energy Transfer Assay
- (2012) H.-Y. Wu et al. JOURNAL OF NEUROSCIENCE
- Protein–RNA interactions: new genomic technologies and perspectives
- (2012) Julian König et al. NATURE REVIEWS GENETICS
- Interactions between estradiol, BDNF and dendritic spines in promoting memory
- (2012) V. Luine et al. NEUROSCIENCE
- Axonal transport and neurodegenerative disease: Can we see the elephant?
- (2012) Lawrence S.B. Goldstein PROGRESS IN NEUROBIOLOGY
- Early and Selective Impairments in Axonal Transport Kinetics of Synaptic Cargoes Induced by Soluble Amyloid β-Protein Oligomers
- (2012) Yong Tang et al. TRAFFIC
- Mitochondrial dynamics in neurodegeneration
- (2012) Kie Itoh et al. TRENDS IN CELL BIOLOGY
- Alzheimer Aβ disrupts the mitotic spindle and directly inhibits mitotic microtubule motors
- (2011) Sergiy I. Borysov et al. CELL CYCLE
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Differential Control of Presynaptic CaMKII Activation and Translocation to Active Zones
- (2011) D. Shakiryanova et al. JOURNAL OF NEUROSCIENCE
- Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases
- (2011) N. M. Kanaan et al. JOURNAL OF NEUROSCIENCE
- Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo
- (2011) Tomohiro Umeda et al. JOURNAL OF NEUROSCIENCE RESEARCH
- The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease
- (2011) Sergio T. Ferreira et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model
- (2011) Sharon A Swanger et al. Molecular Brain
- Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory
- (2010) Daniela Puzzo et al. ANNALS OF NEUROLOGY
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- A Mouse Model of Amyloid Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo
- (2010) T. Tomiyama et al. JOURNAL OF NEUROSCIENCE
- Arc regulates spine morphology and maintains network stability in vivo
- (2010) C. L. Peebles et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport: Fig. 1
- (2010) Keith A. Vossel et al. SCIENCE
- The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells
- (2009) Kazuchika Nishitsuji et al. AMERICAN JOURNAL OF PATHOLOGY
- Picomolar Amyloid- Positively Modulates Synaptic Plasticity and Memory in Hippocampus
- (2009) D. Puzzo et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses
- (2009) Efrat Abramov et al. NATURE NEUROSCIENCE
- TrkB signalling pathways in LTP and learning
- (2009) Liliana Minichiello NATURE REVIEWS NEUROSCIENCE
- Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
- (2009) Shaomin Li et al. NEURON
- Amyloid-β E22Δ variant induces synaptic alteration in mouse hippocampal slices
- (2009) Hiroshi Takuma et al. NEUROREPORT
- Dynactin regulates bidirectional transport of dense-core vesicles in the axon and dendrites of cultured hippocampal neurons
- (2009) D.M. Kwinter et al. NEUROSCIENCE
- The Roles of CaMKII and F-Actin in the Structural Plasticity of Dendritic Spines: A Potential Molecular Identity of a Synaptic Tag?
- (2009) Kenichi Okamoto et al. PHYSIOLOGY
- Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta
- (2009) G. Pigino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia
- (2008) Takami Tomiyama et al. ANNALS OF NEUROLOGY
- p21-activated Kinase-aberrant Activation and Translocation in Alzheimer Disease Pathogenesis
- (2008) Qiu-Lan Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice
- (2008) A. Yuan et al. JOURNAL OF NEUROSCIENCE
- The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity
- (2008) Nichole E. LaPointe et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search