circLARP4 induces cellular senescence through regulating miR-761/RUNX3/p53/p21 signaling in hepatocellular carcinoma

Extracellular vesicle-encapsulated microRNA-761 enhances pazopanib resistance in synovial sarcoma

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Hsa_circ_0007534/miR-761/ZIC5 regulatory loop modulates the proliferation and migration of glioma cells

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Cancer statistics, 2018

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Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

(2018) Debanjan Dhar et al.   CANCER CELL

A Meta-Analysis of the Diagnostic Accuracy of Circular RNAs in Digestive System Malignancy

(2018) Zhiqiang Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells

(2018) Nithila A. Joseph et al.   Journal of Hematology & Oncology

Circular RNAs: a new frontier for cancer diagnosis and therapy

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Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma

(2018) Jian Yu et al.   JOURNAL OF HEPATOLOGY

Circular RNA and its mechanisms in disease: From the bench to the clinic

(2018) Bing Han et al.   PHARMACOLOGY & THERAPEUTICS

Mitochondrial glutamine metabolism via GOT2 supports pancreatic cancer growth through senescence inhibition

(2018) Seungyeon Yang et al.   Cell Death & Disease

MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effect

(2018) Zhiqiang Chen et al.   Cell Death & Disease

circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma

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Circular RNAs in Cancer – Lessons Learned From microRNAs

(2018) Mihnea Dragomir et al.   Frontiers in Oncology

Targeting of the C-Jun/BCL-XL/P21 Axis Accelerates the Switch from Senescence to Apoptosis Upon ROC1 Knockdown in Gastric Cancer Cells

(2018) Ping Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression

(2017) Dan Han et al.   HEPATOLOGY

TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway

(2017) Jian Zheng et al.   Journal of Hematology & Oncology

SASP regulation by noncoding RNA

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Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression

(2017) Jing Zhang et al.   Molecular Cancer

Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics

(2017) Nina Frey et al.   Nature Reviews Gastroenterology & Hepatology

Runx3 plays a critical role in restriction-point and defense against cellular transformation

(2017) X-Z Chi et al.   ONCOGENE

p21: A Two-Faced Genome Guardian

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Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway

(2017) Guihua Wang et al.   Cell Death & Disease

microRNA-761 induces aggressive phenotypes in triple-negative breast cancer cells by repressing TRIM29 expression

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RUNX3 regulates hepatocellular carcinoma cell metastasis via targeting miR-186/E-cadherin/EMT pathway

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MicroRNA-761 is upregulated in hepatocellular carcinoma and regulates tumorigenesis by targeting Mitofusin-2

(2016) Xiaohu Zhou et al.   CANCER SCIENCE

Survival and cost-effectiveness of sorafenib therapy in advanced hepatocellular carcinoma: An analysis of the SEER-Medicare database

(2016) Neehar D. Parikh et al.   HEPATOLOGY

Epigenetic mechanisms regulating the development of hepatocellular carcinoma and their promise for therapeutics

(2016) Faisal Saeed Khan et al.   Hepatology International

The biogenesis and emerging roles of circular RNAs

(2016) Ling-Ling Chen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1

(2016) Amaresh C. Panda et al.   NUCLEIC ACIDS RESEARCH

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

RUNX3 Controls a Metastatic Switch in Pancreatic Ductal Adenocarcinoma

(2015) Martin C. Whittle et al.   CELL

MiR-761 Promotes Progression and Metastasis of Non-Small Cell Lung Cancer by Targeting ING4 and TIMP2

(2015) An Yan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

How do K-RAS-activated cells evade cellular defense mechanisms?

(2015) Y-S Lee et al.   ONCOGENE

Runx3 Inactivation Is a Crucial Early Event in the Development of Lung Adenocarcinoma

(2013) You-Soub Lee et al.   CANCER CELL

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma

(2012) Naoshi Nishida et al.   HEPATOLOGY

Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma

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Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis

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RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells

(2009) Juan Gao et al.   EXPERIMENTAL CELL RESEARCH