Effects of metformin on apoptosis and α-synuclein in a rat model of pentylenetetrazole-induced epilepsy

Evaluation of metformin effects in the chronic phase of spontaneous seizures in pilocarpine model of temporal lobe epilepsy

(2017) Soraya Mehrabi et al.   METABOLIC BRAIN DISEASE

4-Phenylbutyric acid and metformin decrease sensitivity to pentylenetetrazol-induced seizures in a malin knockout model of Lafora disease

(2017) Gentzane Sánchez-Elexpuru et al.   NEUROREPORT

Pharmacological Interventions to Ameliorate Neuropathological Symptoms in a Mouse Model of Lafora Disease

(2015) Arnaud Berthier et al.   MOLECULAR NEUROBIOLOGY

Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice

(2014) Ran-ran Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Canonical Wnt Signaling Pathway in Autism

(2014) Yinghua Zhang et al.   CNS & Neurological Disorders-Drug Targets

Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide

(2014) Krzysztof Łabuzek et al.   Pharmacological Reports

Metformin Attenuates Palmitate-Induced Endoplasmic Reticulum Stress, Serine Phosphorylation of IRS-1 and Apoptosis in Rat Insulinoma Cells

(2014) Laura Simon-Szabó et al.   PLoS One

Metformin induces up-regulation of blood–brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells

(2013) Fuyuko Takata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pentylentetrazole-induced loss of blood–brain barrier integrity involves excess nitric oxide generation by neuronal nitric oxide synthase

(2013) Sonoko Danjo et al.   BRAIN RESEARCH

Ascorbic acid ameliorates seizures and brain damage in rats through inhibiting autophagy

(2013) Yan Dong et al.   BRAIN RESEARCH

The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro

(2013) Marija Dulovic et al.   NEUROBIOLOGY OF DISEASE

Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain

(2013) Marta B. Wisniewska   NEUROCHEMICAL RESEARCH

Cell death and survival mechanisms are concomitantly active in the hippocampus of patients with mesial temporal sclerosis

(2013) N. Dericioglu et al.   NEUROSCIENCE

Gene Expression Profiling of a Hypoxic Seizure Model of Epilepsy Suggests a Role for mTOR and Wnt Signaling in Epileptogenesis

(2013) Joachim Theilhaber et al.   PLoS One

Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts

(2013) Gilles M. Leclerc et al.   PLoS One

Metformin improves healthspan and lifespan in mice

(2013) Alejandro Martin-Montalvo et al.   Nature Communications

Endoplasmic Reticulum Stress and Type 2 Diabetes

(2012) Sung Hoon Back et al.   Annual Review of Biochemistry

Metformin Reduces Endogenous Reactive Oxygen Species and Associated DNA Damage

(2012) C. Algire et al.   Cancer Prevention Research

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Metformin Activates an Atypical PKC-CBP Pathway to Promote Neurogenesis and Enhance Spatial Memory Formation

(2012) Jing Wang et al.   Cell Stem Cell

Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats

(2012) Hiranya Pintana et al.   LIFE SCIENCES

Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice

(2012) Jiejie Li et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells

(2011) Jimmy R. Thériault et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metformin prevents endoplasmic reticulum stress-induced apoptosis through AMPK-PI3K-c-Jun NH2 pathway

(2011) Tae Woo Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

α-Synuclein in Parkinson disease and other neurodegenerative disorders

(2011) Michael Eller et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Metformin differentially activates ER stress signaling pathways without inducing apoptosis

(2011) T. Quentin et al.   Disease Models & Mechanisms

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Proteomic Profiling of the Epileptic Dentate Gyrus

(2010) Aiqing Li et al.   BRAIN PATHOLOGY

Effects of Metformin in Experimental Stroke

(2010) Jun Li et al.   STROKE

Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis

(2009) N. Nath et al.   JOURNAL OF IMMUNOLOGY

Maternal epileptic seizure induced by Pentylenetetrazol: Apoptotic neurodegeneration and decreased GABAB1 receptor expression in prenatal rat brain

(2009) Muhammad Naseer et al.   Molecular Brain

The prevalence of epilepsy and pharmacoresistant epilepsy in adults: A population-based study in a Western European country

(2008) Marie-Christine Picot et al.   EPILEPSIA

Alpha-synuclein multiplications with parkinsonism, dementia or progressive myoclonus?

(2008) Andreas Puschmann et al.   PARKINSONISM & RELATED DISORDERS