Origin and development of oligoadenylate synthetase immune system

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Molecular Mechanisms for the Adaptive Switching Between the OAS/RNase L and OASL/RIG-I Pathways in Birds and Mammals

(2018) Enguang Rong et al.   Frontiers in Immunology

A mutation in the viral sensor 2’-5’-oligoadenylate synthetase 2 causes failure of lactation

(2017) Samantha R. Oakes et al.   PLoS Genetics

Induction of OAS gene family in HIV monocyte infected patients with high and low viral load

(2016) P. Fagone et al.   ANTIVIRAL RESEARCH

Identification of2′-5′-Oligoadenylate Synthetase-LikeGene in Goose: Gene Structure, Expression Patterns, and Antiviral Activity Against Newcastle Disease Virus

(2016) Chao Yang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses

(2016) Yize Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection

(2016) Anshu P. Gounder et al.   PLoS Pathogens

Extracellular 2′5′-oligoadenylate synthetase 2 mediates T-cell receptor CD3-ζchain down-regulation via caspase-3 activation in oral cancer

(2015) Asif A. Dar et al.   IMMUNOLOGY

Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response

(2015) Andrew E. Webb et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3

(2015) Jesse Donovan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Activation Mechanism of 2′-5′-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity

(2015) Jan Lohöfener et al.   STRUCTURE

Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape

(2015) Dustin C. Hancks et al.   PLoS Genetics

The 2'-5'-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2'-5'-Oligoadenylates Required for RNase L Activation

(2014) M. S. Ibsen et al.   JOURNAL OF VIROLOGY

IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

(2014) Lam-Tung Nguyen et al.   MOLECULAR BIOLOGY AND EVOLUTION

BEAST 2: A Software Platform for Bayesian Evolutionary Analysis

(2014) Remco Bouckaert et al.   PLoS Computational Biology

Enzymatically active 2′,5′-oligoadenylate synthetases are widely distributed among Metazoa, including protostome lineage

(2013) Mailis Päri et al.   BIOCHIMIE

The duck genome and transcriptome provide insight into an avian influenza virus reservoir species

(2013) Yinhua Huang et al.   NATURE GENETICS

Neofunctionalization of young duplicate genes in Drosophila

(2013) R. Assis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein docking using case-based reasoning

(2013) Anisah W. Ghoorah et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Expressed 2–5A synthetase genes and pseudogenes in the marine sponge Geodia barretti

(2011) Kerli Vallmann et al.   GENE

Identification of an additional two-cysteine containing type I interferon in rainbow trout Oncorhynchus mykiss provides evidence of a major gene duplication event within this gene family in teleosts

(2009) Mingxian Chang et al.   IMMUNOGENETICS

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

2’-5’ Oligoadenylate synthetase shares active site architecture with the archaeal CCA-adding enzyme

(2008) S. Torralba et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Defensins and the convergent evolution of platypus and reptile venom genes

(2008) C. M. Whittington et al.   GENOME RESEARCH

Sponge OAS has a distinct genomic structure within the 2-5A synthetase family

(2008) Tõnu Reintamm et al.   MOLECULAR GENETICS AND GENOMICS

The 2′-5′-oligoadenylate synthetase in the lowest metazoa: isolation, cloning, expression and functional activity in the sponge Lubomirskia baicalensis

(2007) Heinz C. Schröder et al.   MOLECULAR IMMUNOLOGY