Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells

Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway

(2017) M-J Wu et al.   ONCOGENE

Retinoic acid and arsenic trioxide in the treatment of acute promyelocytic leukemia: current perspectives

(2017) Derek McCulloch et al.   OncoTargets and Therapy

Profiling of the transcriptional response to all-trans retinoic acid in breast cancer cells reveals RARE-independent mechanisms of gene expression

(2017) Krysta Mila Coyle et al.   Scientific Reports

The hypoxic tumor microenvironment: A driving force for breast cancer progression

(2016) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

All-Trans Retinoic Acid Attenuates Hypoxia-Induced Injury in NRK52E Cells via Inhibiting NF-κB/VEGF and TGF-β2/VEGF Pathway

(2016) Yong Xu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ductal carcinoma in situ of the breast: the importance of morphologic and molecular interactions

(2016) Stacey K. Mardekian et al.   HUMAN PATHOLOGY

PLC-β2 is modulated by low oxygen availability in breast tumor cells and plays a phenotype dependent role in their hypoxia-related malignant potential

(2016) Federica Brugnoli et al.   MOLECULAR CARCINOGENESIS

Current standard treatment of adult acute promyelocytic leukaemia

(2015) Francesco Lo-Coco et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RAR  expression

(2015) F. Centritto et al.   EMBO Molecular Medicine

All-trans-retinoic Acid Modulates the Plasticity and Inhibits the Motility of Breast Cancer Cells

(2015) Adriana Zanetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Clinical Significance of Hypoxia in Human Cancers

(2015) Neesha Dhani et al.   SEMINARS IN NUCLEAR MEDICINE

Retinoids and breast cancer: From basic studies to the clinic and back again

(2014) Enrico Garattini et al.   CANCER TREATMENT REVIEWS

Metastatic Stem Cells: Sources, Niches, and Vital Pathways

(2014) Thordur Oskarsson et al.   Cell Stem Cell

All trans-retinoic acid (ATRA) induces re-differentiation of early transformed breast epithelial cells

(2014) MARIA F. ARISI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Ductal carcinomain situof the breast: morphological and molecular features implicated in progression

(2013) Dirce M. Carraro et al.   BIOSCIENCE REPORTS

Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast

(2013) Aram S. A. van Brussel et al.   BREAST CANCER RESEARCH AND TREATMENT

Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway in Cancer Prevention and Treatment

(2013) R. M. Connolly et al.   CLINICAL CANCER RESEARCH

Snail/beta-catenin signaling protects breast cancer cells from hypoxia attack

(2013) Alexander M. Scherbakov et al.   EXPERIMENTAL CELL RESEARCH

Role of hypoxia-inducible factors in breast cancer metastasis

(2013) Daniele M Gilkes et al.   Future Oncology

Epithelial-mesenchymal transition increases during the progression of in situ to invasive basal-like breast cancer

(2013) Yoomi Choi et al.   HUMAN PATHOLOGY

Retinoids and their biological effects against cancer

(2013) Fatemeh Alizadeh et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells

(2013) Murielle Mimeault et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133high to CD133low phenotype and reduces the CD133-related invasiveness

(2013) Federica Brugnoli et al.   Molecular Cancer

Progression from ductal carcinoma in situ to invasive breast cancer: Revisited

(2013) Catherine F. Cowell et al.   Molecular Oncology

Hypoxia-Inducible Factors Activate CD133 Promoter through ETS Family Transcription Factors

(2013) Shunsuke Ohnishi et al.   PLoS One

Retinoic acid increases hypoxia-inducible factor-1α through intracrine prostaglandin E2 signaling in human renal proximal tubular cells HK-2

(2012) Ana B. Fernández-Martínez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity

(2012) Margaret J. Currie et al.   HUMAN PATHOLOGY

Hypoxic Conditions Induce a Cancer-Like Phenotype in Human Breast Epithelial Cells

(2012) Marica Vaapil et al.   PLoS One

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

(2012) S. J. Conley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

The Role of Breast Cancer Stem Cells in Metastasis and Therapeutic Implications

(2011) Marco A. Velasco-Velázquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells

(2011) Valeria Bertagnolo et al.   CELL AND TISSUE RESEARCH

Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways

(2011) Nadine Rohwer et al.   DRUG RESISTANCE UPDATES

Retinoid pathway and cancer therapeutics

(2010) Nathan Bushue et al.   ADVANCED DRUG DELIVERY REVIEWS