Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases

Modeling autism in non-human primates: Opportunities and challenges

(2018) Hui Zhao et al.   Autism Research

Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination

(2018) Yiqiang Cui et al.   CELL RESEARCH

Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing

(2018) Xuan Yao et al.   CELL RESEARCH

Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos

(2018) Bin Gu et al.   NATURE BIOTECHNOLOGY

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

(2018) Emma Haapaniemi et al.   NATURE MEDICINE

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

(2016) Van Trung Chu et al.   BMC BIOTECHNOLOGY

Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering

(2016) Sisi Lai et al.   PLoS One

Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression

(2016) Dongshan Yang et al.   Scientific Reports

Rosa26-targeted sheep gene knock-in via CRISPR-Cas9 system

(2016) Mingming Wu et al.   Scientific Reports

Utilization of TALEN and CRISPR/Cas9 technologies for gene targeting and modification

(2015) Jiali Pu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

CRISPR/Cas9-mediatedDax1knockout in the monkey recapitulates human AHC-HH

(2015) Yu Kang et al.   HUMAN MOLECULAR GENETICS

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9

(2015) Yongchang Chen et al.   HUMAN MOLECULAR GENETICS

MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems

(2015) Tetsushi Sakuma et al.   Nature Protocols

Brains, Genes, and Primates

(2015) Juan Carlos Izpisua Belmonte et al.   NEURON

Gene targeting by TALEN-induced homologous recombination in goats directs production of β-lactoglobulin-free, high-human lactoferrin milk

(2015) Chenchen Cui et al.   Scientific Reports

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

(2014) Yuyu Niu et al.   CELL

Efficient homologous recombination-mediated genome engineering in zebrafish using TALE nucleases

(2014) J. Shin et al.   DEVELOPMENT

Establishment of a Rabbit Oct4 Promoter-Based EGFP Reporter System

(2014) Longquan Quan et al.   PLoS One

Generation of a monkey with MECP2 mutations by TALEN-based gene targeting

(2014) Zhen Liu et al.   Neuroscience Bulletin

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells

(2013) Su Mi Choi et al.   HEPATOLOGY

Transcription Activator-like Effector Nuclease (TALEN)-mediated Gene Correction in Integration-free β-Thalassemia Induced Pluripotent Stem Cells

(2013) Ning Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TALEN-based Gene Correction for Epidermolysis Bullosa

(2013) Mark J Osborn et al.   MOLECULAR THERAPY

Nuclease-mediated gene editing by homologous recombination of the human globin locus

(2013) Richard A. Voit et al.   NUCLEIC ACIDS RESEARCH

Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease

(2012) Ning Sun et al.   Molecular BioSystems

Tracking genome engineering outcome at individual DNA breakpoints

(2011) Michael T Certo et al.   NATURE METHODS

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

Transgenic rhesus monkeys produced by gene transfer into early-cleavage–stage embryos using a simian immunodeficiency virus-based vector

(2010) Yuyu Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of transgenic monkeys with human inherited genetic disease

(2009) Anthony W.S. Chan et al.   METHODS

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Development of a stable, early stage unilateral model of Parkinson's disease in middle-aged rhesus monkeys

(2008) Feng Ding et al.   EXPERIMENTAL NEUROLOGY

Towards a transgenic model of Huntington’s disease in a non-human primate

(2008) Shang-Hsun Yang et al.   NATURE