An Integrated Approach to Aggregate Control for Therapeutic Bispecific Antibodies Using an Improved Three Column Mab Platform-Like Purification Process

Choosing the right protein A affinity chromatography media can remove aggregates efficiently

(2016) Tomokazu Yada et al.   Biotechnology Journal

Choosing the right protein A affinity chromatography media can remove aggregates efficiently

(2016) Tomokazu Yada et al.   Biotechnology Journal

Advances in inline quantification of co-eluting proteins in chromatography: Process-data-based model calibration and application towards real-life separation issues

(2015) Nina Brestrich et al.   BIOTECHNOLOGY AND BIOENGINEERING

Clarification technologies for monoclonal antibody manufacturing processes: Current state and future perspectives

(2015) Nripen Singh et al.   BIOTECHNOLOGY AND BIOENGINEERING

Bispecific antibodies

(2015) Roland E. Kontermann et al.   DRUG DISCOVERY TODAY

Bispecific antibodies and their applications

(2015) Gaowei Fan et al.   Journal of Hematology & Oncology

Alternative molecular formats and therapeutic applications for bispecific antibodies

(2015) Christoph Spiess et al.   MOLECULAR IMMUNOLOGY

Separation of recombinant antibodies from DNA using divalent cations

(2014) Peter Satzer et al.   ENGINEERING IN LIFE SCIENCES

Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity

(2014) Timothy M. Pabst et al.   JOURNAL OF CHROMATOGRAPHY A

Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes

(2013) Yun Kenneth Kang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Purification of antibodies by precipitating impurities using Polyethylene Glycol to enable a two chromatography step process

(2013) Glen Giese et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Purification of monoclonal antibodies by hydrophobic interaction chromatography under no-salt conditions

(2013) Sanchayita Ghose et al.   mAbs

The structure of dual-variable-domain immunoglobulin molecules alone and bound to antigen

(2013) Ivan Correia et al.   mAbs

Dual targeting strategies with bispecific antibodies

(2012) Roland Kontermann   mAbs

IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines

(2011) Steven C.L. Ho et al.   JOURNAL OF BIOTECHNOLOGY

Technology trends in antibody purification

(2011) Pete Gagnon   JOURNAL OF CHROMATOGRAPHY A

Effects of solution environment on mammalian cell fermentation broth properties: Enhanced impurity removal and clarification performance

(2010) Matthew Westoby et al.   BIOTECHNOLOGY AND BIOENGINEERING

Purification of singly PEGylated α-lactalbumin using charged ultrafiltration membranes

(2010) Krisada Ruanjaikaen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Glucocorticoid receptor-mediated reduction of IgG-fusion protein aggregation in Chinese hamster ovary cells

(2010) Yueming Qian et al.   BIOTECHNOLOGY PROGRESS

Recovery and purification process development for monoclonal antibody production

(2010) Hui F. Liu et al.   mAbs

Recent advances in large-scale production of monoclonal antibodies and related proteins

(2010) Abhinav A. Shukla et al.   TRENDS IN BIOTECHNOLOGY

Bispecific T-Cell Engaging Antibodies for Cancer Therapy

(2009) P. A. Baeuerle et al.   CANCER RESEARCH

Application of high-performance tangential flow filtration (HPTFF) to the purification of a human pharmaceutical antibody fragment expressed inEscherichia coli

(2008) Bénédicte Lebreton et al.   BIOTECHNOLOGY AND BIOENGINEERING